GSK‐3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and β‐catenin stabilisation without elevation of glycogen synthase activity

scientific article published on November 2, 2001

GSK‐3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and β‐catenin stabilisation without elevation of glycogen synthase activity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-5793(01)02990-8
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2FS0014-5793(01)02990-8
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2FS0014-5793%2801%2902990-8
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/S0014-5793%2801%2902990-8
https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1016/S0014-5793%2801%2902990-8
P698PubMed publication ID11696357
P5875ResearchGate publication ID11658765

P50authorBen BaxQ67804404
P2093author name stringM. J. Brown
A. D. Reith
T. Hagen
D. A. Cross
S. Frame
A. A. Culbert
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Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissueQ73241292
Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawalQ73575616
Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancerQ77565725
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinaseQ24291138
GBP, an Inhibitor of GSK-3, Is Implicated in Xenopus Development and OncogenesisQ24309150
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -cateninQ24313571
Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3βQ24319688
Signal transduction by the Wnt family of ligandsQ24530639
Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomasQ24532079
Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.Q24534260
A simplified system for generating recombinant adenovirusesQ24682328
A genetic model for colorectal tumorigenesisQ27860582
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase BQ27860731
A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-cateninQ28115262
The Hormonal Control of Glycogen Metabolism in Mammalian Muscle by Multivalent PhosphorylationQ28254330
Overexpression of the mouse dishevelled-1 protein inhibits GSK-3beta-mediated phosphorylation of tau in transfected mammalian cellsQ28504627
Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complexQ28609062
Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specificationQ28640539
Glycogen Synthase from Rabbit Skeletal MuscleQ29301807
Wnt signaling: a common theme in animal developmentQ29547527
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleusQ29620188
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcriptionQ31462537
Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathwaysQ33814311
Regulation of glycogen synthase kinase 3beta and downstream Wnt signaling by axinQ33959834
Neuronal death and GSK-3beta: a tau fetish?Q34224603
Regulation of GSK-3: a cellular multiprocessorQ34299875
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic miceQ34449486
Bridging of β-catenin and glycogen synthase kinase-3β by Axin and inhibition of β-catenin-mediated transcriptionQ35977699
Domains of tau protein, differential phosphorylation, and dynamic instability of microtubulesQ40665458
Tau phosphorylation at serine 396 and serine 404 by human recombinant tau protein kinase II inhibits tau's ability to promote microtubule assemblyQ40878824
Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.Q40954159
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.Q41423732
Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from deathQ43560460
Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neuronsQ48658321
The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons.Q48712746
Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cellsQ52177288
Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawalQ54415298
Phosphorylation Sites on Tau Identified by Nanoelectrospray Mass SpectrometryQ55919559
Glycogen Synthase Kinase-3 from Rabbit Skeletal MuscleQ56456617
Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domainQ60603639
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
transport proteinQ2111029
neoplasm proteinQ66894191
SB-415286Q27088727
overexpressionQ61643320
P304page(s)288-294
P577publication date2001-11-01
2001-11-02
P1433published inFEBS LettersQ1388051
P1476titleGSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and beta-catenin stabilisation without elevation of glycogen synthase activity
GSK‐3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and β‐catenin stabilisation without elevation of glycogen synthase activity
P478volume507

Reverse relations

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