Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism

scientific article published on 15 January 2002

Hypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111222200
P698PubMed publication ID11792702

P50authorRobert L RaffaiQ93026509
P2093author name stringKarl H Weisgraber
P2860cites workApolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phaseQ24318760
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnantsQ24564846
Apolipoprotein E: far more than a lipid transport proteinQ28204471
Apolipoprotein E: cholesterol transport protein with expanding role in cell biologyQ28294791
Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein EQ28508278
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cellsQ28509783
Mice with reduced NMDA receptor expression display behaviors related to schizophreniaQ28510751
A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerveQ28579544
Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" miceQ28587691
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1Q28594951
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Abnormal blood vessel development and lethality in embryos lacking a single VEGF alleleQ29547733
Inducible gene targeting in miceQ29614544
An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombinationQ29615355
Low levels of extrahepatic nonmacrophage ApoE inhibit atherosclerosis without correcting hypercholesterolemia in ApoE-deficient miceQ30900960
Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E.Q31452265
Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantationQ34225777
Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantationQ35753356
Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null miceQ35765799
Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cellsQ37011453
Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytesQ37375894
Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic miceQ40336543
Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissueQ41747109
Expression of the apolipoprotein E gene in the skin is controlled by a unique downstream enhancerQ42499003
Two hepatic enhancers, HCR.1 and HCR.2, coordinate the liver expression of the entire human apolipoprotein E/C-I/C-IV/C-II gene clusterQ44858774
Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemiaQ46345830
Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.Q52186654
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)11064-11068
P577publication date2002-01-15
P1433published inJournal of Biological ChemistryQ867727
P1476titleHypomorphic apolipoprotein E mice: a new model of conditional gene repair to examine apolipoprotein E-mediated metabolism
P478volume277

Reverse relations

cites work (P2860)
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