Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance

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Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(02)08094-7
P698PubMed publication ID11937183

P50authorWilly RozenbaumQ2945169
Hubert VidalQ33112025
P2093author name stringMartine Laville
Corinne Vigouroux
Jacqueline Capeau
Martine Caron
Mustapha Maachi
Martine Auclair
Philippe Levan
Pierre Marie Girard
Jacqueline Luboinski
Jean Philippe Bastard
Véronique Jan
P2860cites workDifferential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cellsQ24561820
Surgical implantation of adipose tissue reverses diabetes in lipoatrophic miceQ24620943
Metabolic effects of indinavir in healthy HIV-seronegative menQ28366603
Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetesQ33957444
Adverse effects of antiretroviral therapyQ34071132
LipodystrophiesQ34110938
Mitochondrial toxicity hypothesis for lipoatrophy: a refutationQ34198112
Metabolic complications associated with antiretroviral therapyQ34305866
Life without white fat: a transgenic mouseQ35210661
Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophyQ35210714
An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responsesQ36638199
Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolismQ39446637
Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitorsQ40851323
Promoter analysis of the mouse sterol regulatory element-binding protein-1c geneQ40864894
TNF-alpha inhibits 3T3-L1 adipocyte differentiation without downregulating the expression of C/EBPbeta and deltaQ42827195
The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistanceQ42828632
Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes.Q43618955
Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathwayQ43690470
HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleusQ43730373
A single-nucleotide polymorphism in the sterol-regulatory element-binding protein 1c gene is predictive of HIV-related hyperlipoproteinaemiaQ43766799
Autologous fat transplantationQ44203104
Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort studyQ44820677
Serum levels of tumor necrosis factor-alpha (TNF alpha) and soluble TNF receptors in human immunodeficiency virus type 1 infection--correlations to clinical, immunologic, and virologic parametersQ45783344
Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes.Q51554572
Effects of troglitazone on insulin sensitivity in HIV-infected patients with protease inhibitor-associated diabetes mellitus.Q51556296
Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects.Q54059188
The use of the reverse transcription-competitive polymerase chain reaction to investigate the in vivo regulation of gene expression in small tissue samplesQ73123144
Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophyQ73187597
Tumor necrosis factor-alpha induces apoptosis of human adipose cellsQ73929085
Adipose tissue as an endocrine and paracrine organQ77758550
P433issue9311
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
preproinsulinQ7240673
insulin resistanceQ1053470
P304page(s)1026-1031
P577publication date2002-03-01
P1433published inThe LancetQ939416
P1476titleAssociation between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance
P478volume359

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