Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action.

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Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JNR.10209
P698PubMed publication ID11948667

P50authorMasayasu MatsumotoQ123086885
Shigeru TanakaQ70457955
Kazuo KitagawaQ90069653
P2093author name stringMasatsugu Hori
Tsutomu Sasaki
Toshiho Ohtsuki
Takehiko Yanagihara
Kohji Matsushita
Keisuke Kuwabara
Ken-Ichiro Takasawa
P2860cites workPathobiology of ischaemic stroke: an integrated viewQ28141682
Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the ratQ28569838
Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiencyQ28587242
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein EQ29615236
Impact of apoE deficiency on oxidative insults and antioxidant levels in the brainQ31878389
Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat.Q32118778
Caspases as treatment targets in stroke and neurodegenerative diseasesQ33598614
Reactive oxygen radicals in signaling and damage in the ischemic brainQ33930675
Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and strokeQ35802442
Glutamate and the pathophysiology of hypoxic--ischemic brain damageQ38161694
Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptidesQ41172424
Staurosporine-induced neuronal apoptosis.Q41672506
Deficiency of intercellular adhesion molecule 1 attenuates microcirculatory disturbance and infarction size in focal cerebral ischemiaQ47274599
Phosphoinositide hydrolysis activated by muscarinic or glutamatergic, but not adrenergic, receptors is impaired in ApoE-deficient mice and by hydrogen peroxide and peroxynitriteQ47774606
NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insultsQ48155678
Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouseQ48220117
Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemiaQ48234274
Amelioration of hippocampal neuronal damage after global ischemia by neuronal overexpression of BCL-2 in transgenic mice.Q48338267
Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic miceQ48492024
DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat.Q48621500
Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemiaQ48664618
Delayed, but marked, expression of apolipoprotein E is involved in tissue clearance after cerebral infarctionQ48746786
Protective effect of alpha-tocopherol on ischemic neuronal damage in the gerbil hippocampusQ49059353
Cystatin C and apolipoprotein E immunoreactivities in CA1 neurons in ischemic gerbil hippocampusQ49114133
Increased levels of intracellular iron in the brains of ApoE-deficient mice with closed head injury.Q52024859
Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats.Q52539869
Induction of apolipoprotein E mRNA in the hippocampus of the gerbil after transient global ischemia.Q53212645
Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.Q54039074
Intraventricular Infusion of Apolipoprotein E Ameliorates Acute Neuronal Damage after Global Cerebral Ischemia in MiceQ64462201
Increased amyloid protein precursor and apolipoprotein E immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbilsQ71736000
Complete cerebral ischemia with short-term survival in rat induced by cardiac arrest. II. Extracellular and intracellular accumulation of apolipoproteins E and J in the brainQ72346999
Distinct alterations in phospholipid metabolism in brains of apolipoprotein E-deficient miceQ73111295
A mechanism for the neuroprotective effect of apolipoprotein E: isoform-specific modification by the lipid peroxidation product 4-hydroxynonenalQ73593736
No effect of apolipoprotein E on neuronal cell death due to excitotoxic and apoptotic agents in vitro and neonatal hypoxic ischaemia in vivoQ74187410
Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient miceQ77407922
P433issue2
P304page(s)226-232
P577publication date2002-04-01
P1433published inJournal of Neuroscience ResearchQ6295654
P1476titleProtective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action
P478volume68

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cites work (P2860)
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