Apolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis

scientific article published on 10 December 2012

Apolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2012.12.003
P698PubMed publication ID23238080
P5875ResearchGate publication ID233913752

P2093author name stringShuang Tang
Shuai Zhou
Chun Zeng
Xiaochuan Sun
Haitao Wu
Zhaohua Tang
Xuehua Xiong
P2860cites workApolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyQ24604376
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS modelQ24631645
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Glycosylation and sialylation of macrophage-derived human apolipoprotein E analyzed by SDS-PAGE and mass spectrometry: evidence for a novel site of glycosylation on Ser290.Q34122180
Astrocytic beta2-adrenergic receptors and multiple sclerosisQ35684818
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Glutamate-mediated glial injury: mechanisms and clinical importanceQ36277315
Comparison of alterations in amino acids content in cultured astrocytes or neurons exposed to methylmercury separately or in co-cultureQ37188541
Astrocyte-neuron interactions in neurological disordersQ37361072
The release and uptake of excitatory amino acidsQ37607591
Proton pump inhibitor lansoprazole is a nuclear liver X receptor agonistQ39495324
Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytesQ40497562
A liver X receptor and retinoid X receptor heterodimer mediates apolipoprotein E expression, secretion and cholesterol homeostasis in astrocytesQ40599853
Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: neuroprotective effect of FK506.Q43143043
Protective effect of apolipoprotein E against ischemic neuronal injury is mediated through antioxidant action.Q43956277
Protective effect of apolipoprotein E-mimetic peptides on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cell cultures.Q44297276
Apolipoprotein E protects against oxidative stress in mixed neuronal-glial cell cultures by reducing glutamate toxicityQ44583358
The roles of aquaporin-4 in brain edema following neonatal hypoxia ischemia and reoxygenation in a cultured rat astrocyte model.Q48201340
Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouseQ48220117
Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemiaQ48234274
Different expression of low density lipoprotein receptor and ApoE between young adult and old rat brains after ischemiaQ48279222
Neuroprotectant FK506 inhibits glutamate-induced apoptosis of astrocytes in vitro and in vivo.Q48382202
Hypoxia-induced astrocytic reaction and increased vascular permeability in the rat cerebellumQ48420604
NAP enhances neurodevelopment of newborn apolipoprotein E-deficient mice subjected to hypoxiaQ48478314
Mechanical injured neurons stimulate astrocytes to express apolipoprotein E through ERK pathwayQ48596971
Ischemia-induced apoptosis in primary cultures of astrocytes.Q51064571
Hypoxia suppresses glutamate transport in astrocytes.Q52578364
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectastrocyteQ502961
hypoxiaQ105688
P304page(s)254-258
P577publication date2012-12-10
P1433published inFEBS LettersQ1388051
P1476titleApolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis
P478volume587

Reverse relations

cites work (P2860)
Q336231323,4-oxo-isopropylidene-shikimic acid inhibits cerebral ischemia-induced oxidative stress and neuronal apoptosis in rats
Q48279133APOEε4 increases trauma induced early apoptosis via reducing delayed rectifier K(+) currents in neuronal/glial co-cultures model
Q35907609An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer's disease
Q41159086ApoE Influences the Blood-Brain Barrier Through the NF-κB/MMP-9 Pathway After Traumatic Brain Injury
Q37315219ApoE deficiency promotes colon inflammation and enhances inflammatory potential oxidized-LDL and TNF-α in colon epithelial cells
Q47281896Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid.
Q36489612Apolipoprotein E-Mimetic COG1410 Reduces Acute Vasogenic Edema following Traumatic Brain Injury
Q30924126Bexarotene reduces blood-brain barrier permeability in cerebral ischemia-reperfusion injured rats
Q33771783Cerebrospinal fluid apolipoprotein E and phospholipid transfer protein activity are reduced in multiple sclerosis; relationships with the brain MRI and CSF lipid variables
Q38763152Gene expression related to oxidative stress in the heart of mice after intestinal ischemia
Q37377112Morphine Protects Spinal Cord Astrocytes from Glutamate-Induced Apoptosis via Reducing Endoplasmic Reticulum Stress
Q51330937Orexin-A promotes Glu uptake by OX1R/PKCα/ERK1/2/GLT-1 pathway in astrocytes and protects co-cultured astrocytes and neurons against apoptosis in anoxia/hypoglycemic injury in vitro.
Q37636579Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity
Q26828875Role of non-neuronal cells in body weight and appetite control
Q27303152Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease
Q41661095Thirty Minutes of Hypobaric Hypoxia Provokes Alterations of Immune Response, Haemostasis, and Metabolism Proteins in Human Serum
Q89596058Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk

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