Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function.

scientific article published in August 2002

Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.22-16-06876.2002
P932PMC publication ID6757859
P698PubMed publication ID12177185

P2093author name stringKoichi Furukawa
Graham M O'Hanlon
Hugh J Willison
Jaap J Plomp
Roland W M Bullens
Keiko Furukawa
Peter C Molenaar
Eric Wagner
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Organization of ganglioside synthesis in the Golgi apparatusQ33538124
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Monoclonal antibodies raised against Guillain-Barré syndrome-associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations.Q33853670
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Cerebellar neurons lacking complex gangliosides degenerate in the presence of depolarizing levels of potassiumQ34595643
Ultrastructural localization of cell membrane G M1 ganglioside by cholera toxinQ35049788
SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis.Q35888471
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defectsQ36399818
A bacterium lipopolysaccharide that elicits Guillain-Barré syndrome has a GM1 ganglioside-like structureQ38314715
Ganglioside structures and distribution: Are they localized at the nerve ending?Q39783348
Gangliosides and synaptic transmission.Q40090012
Molecular aspects of tetanus and botulinum neurotoxin poisoningQ40418282
Calcium-ganglioside interactions and synaptic plasticity: effect of calcium on specific ganglioside/peptide (valinomycin, gramicidin A)-complexes in mixed mono- and bilayersQ41079344
Gangliosides mediate inhibitory effects of tetanus and botulinum A neurotoxins on exocytosis in chromaffin cellsQ42499734
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Gangliosides as receptors for biological toxins: development of sensitive fluoroimmunoassays using ganglioside-bearing liposomesQ46269287
Effect of the mono- and tetra-sialogangliosides, GM1 and GQ1b, on long-term potentiation in the CA1 hippocampal neurons of the guinea pig.Q46977545
The binding of botulinum toxin to membrane lipids: phospholipids and proteolipidQ47746062
Gangliosides and sialylcholesterol as modulators of synaptic functions.Q47825859
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Gangliosides enhance KCl-induced Ca2+ influx and acetylcholine release in brain synaptosomesQ48659663
Lectins from Triticum vulgaris and Limax flavus are universal antagonists of botulinum neurotoxin and tetanus toxinQ48669080
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Gangliosides improve synaptic transmission in dentate gyrus of hippocampal rat slicesQ49135469
The subcellular localization of gangliosides in the brainQ51212607
Non-linear summation of end-plate potentials in the frog and mouse.Q52741737
A quantitative description of end-plate currentsQ52979944
Gangliosides affect membrane-channel activities dependent on ambient temperature.Q53907052
Gangliosides are the binding substances in neural cells for tetanus and botulinum toxins in miceQ57539150
Anti-GQ1b antibodies and evoked acetylcholine release at mouse motor endplatesQ61633257
Ganglioside inactivation of botulinum toxinQ68632759
Botulinum A neurotoxin unlike tetanus toxin acts via a neuraminidase sensitive structureQ68976927
TLC immunostaining characterization of Clostridium botulinum type A neurotoxin binding to gangliosides and free fatty acidsQ69513387
Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barré syndrome: clinical and immunohistochemical studiesQ70514545
Interaction between Clostridium botulinum neurotoxin and gangliosidesQ71499646
The influence of exogenous gangliosides on the dynamics of the development of prolonged posttetanic potentiationQ72586382
Serum factor in Miller-Fisher variant of Guillain-Barré syndrome and neurotransmitter releaseQ72667720
Structure-based sequence alignment for the beta-trefoil subdomain of the clostridial neurotoxin family provides residue level information about the putative ganglioside binding siteQ73039693
Pre- and postsynaptic blockade of neuromuscular transmission by Miller-Fisher syndrome IgG at mouse motor nerve terminalsQ77348546
Miller Fisher anti-GQ1b antibodies: alpha-latrotoxin-like effects on motor end platesQ78170867
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectneuromuscular junctionQ776995
autoantibodyQ785022
P304page(s)6876-6884
P577publication date2002-08-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleComplex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function
P478volume22

Reverse relations

cites work (P2860)
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