Genetic stability of Rift Valley fever virus MP-12 vaccine during serial passages in culture cells

scientific article published on 17 July 2017

Genetic stability of Rift Valley fever virus MP-12 vaccine during serial passages in culture cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1090448725
P356DOI10.1038/S41541-017-0021-9
P8608Fatcat IDrelease_vlzgrbtirjhylecbqn26wyenne
P932PMC publication ID5627234
P698PubMed publication ID29167748

P50authorNandadeva LokugamageQ117812116
Tetsuro IkegamiQ40311693
P2860cites workVACCINE-DERIVED POLIOVIRUSES AND THE ENDGAME STRATEGY FOR GLOBAL POLIO ERADICATION *Q22255613
Viral mutation ratesQ24611162
Rift Valley fever virus NSs protein functions and the similarity to other bunyavirus NSs proteinsQ26745530
The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainmentQ26830833
Homologous recombination in negative sense RNA virusesQ27024104
Complete Genome Analysis of 33 Ecologically and Biologically Diverse Rift Valley Fever Virus Strains Reveals Widespread Virus Movement and Low Genetic Diversity due to Recent Common AncestryQ27478367
The use of veterinary vaccines for prevention and control of Rift Valley fever: memorandum from a WHO/FAO meetingQ27486846
RNA polymerase I-mediated expression of viral RNA for the rescue of infectious virulent and avirulent Rift Valley fever virusesQ27487321
Safety and Efficacy Profile of Commercial Veterinary Vaccines against Rift Valley Fever: A Review StudyQ28066283
Body temperature of C57BL/6J mice with ageQ71352791
Live attenuated vaccines: Historical successes and current challengesQ28082036
Characterization of Rift Valley fever virus MP-12 strain encoding NSs of Punta Toro virus or sandfly fever Sicilian virusQ28486276
Reversion of Cold-Adapted Live Attenuated Influenza Vaccine into a Pathogenic VirusQ30390811
Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell linesQ30502375
TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.Q33198557
A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells.Q33316823
Rift Valley fever epidemic in Saudi Arabia: epidemiological, clinical, and laboratory characteristicsQ33357041
Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylationQ33406230
Challenges and Practices in Building and Implementing Biosafety and Biosecurity Programs to Enable Basic and Translational Research with Select Agents.Q33699916
Altered virulence of vaccine strains of measles virus after prolonged replication in human tissue.Q33821235
Viral nucleic acids in live-attenuated vaccines: detection of minority variants and an adventitious virusQ33877518
Host alternation is necessary to maintain the genome stability of rift valley fever virusQ33918307
Rift Valley fever virus(Bunyaviridae: Phlebovirus): an update on pathogenesis, molecular epidemiology, vectors, diagnostics and preventionQ33960690
An investigation of a major outbreak of Rift Valley fever in Kenya: 2006-2007Q34034053
History of vaccinationQ34119899
Rift Valley fever virus vaccine lacking the NSs and NSm genes is safe, nonteratogenic, and confers protection from viremia, pyrexia, and abortion following challenge in adult and pregnant sheepQ34221766
Attenuated vaccines can recombine to form virulent field virusesQ34288335
Rift Valley Fever Virus MP-12 Vaccine Is Fully Attenuated by a Combination of Partial Attenuations in the S, M, and L Segments.Q34475358
Dual functions of Rift Valley fever virus NSs protein: inhibition of host mRNA transcription and post-transcriptional downregulation of protein kinase PKR.Q35107614
Molecular epidemiology of Rift Valley fever virusQ35849036
Evaluation of the Efficacy, Potential for Vector Transmission, and Duration of Immunity of MP-12, an Attenuated Rift Valley Fever Virus Vaccine Candidate, in Sheep.Q35902010
The dominant-negative inhibition of double-stranded RNA-dependent protein kinase PKR increases the efficacy of Rift Valley fever virus MP-12 vaccineQ36155392
Genetic subpopulations of Rift Valley fever virus strains ZH548 and MP-12 and recombinant MP-12 strainsQ36414512
Rift Valley fever MP-12 vaccine Phase 2 clinical trial: Safety, immunogenicity, and genetic characterization of virus isolates.Q36514844
The L, M, and S Segments of Rift Valley Fever Virus MP-12 Vaccine Independently Contribute to a Temperature-Sensitive PhenotypeQ36694012
Toscana virus NSs protein promotes degradation of double-stranded RNA-dependent protein kinaseQ36759758
Transcriptional and posttranscriptional regulation of exogenous human beta interferon gene in simian cells defective in interferon synthesisQ36916391
Rift Valley fever virus MP-12 vaccine encoding Toscana virus NSs retains neuroinvasiveness in miceQ37006803
Mutational Analysis of the Rift Valley Fever Virus Glycoprotein Precursor Proteins for Gn Protein Expression.Q37049951
Quantitative modeling of virus evolutionary dynamics and adaptation in serial passages using empirically inferred fitness landscapesQ37547542
Vaccines in veterinary medicine: a brief review of history and technologyQ37752963
The double-edged sword: How evolution can make or break a live-attenuated virus vaccineQ37999021
The role of mutational robustness in RNA virus evolutionQ38092577
Designing cell lines for viral vaccine production: Where do we stand?Q38436738
Vaccination of alpacas against Rift Valley fever virus: Safety, immunogenicity and pathogenicity of MP-12 vaccine.Q39066685
NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinaseQ39195523
The Rift Valley fever epizootic in Egypt 1977–1978 1. Description of the epizootic and virological studiesQ39240187
Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSsQ39601913
Immunogenicity and safety of an inactivated Rift Valley fever vaccine in a 19-year study.Q39778317
Recombination between vaccine and field strains of canine parvovirus is revealed by isolation of virus in canine and feline cell culturesQ39898767
T7 RNA polymerase-dependent and -independent systems for cDNA-based rescue of Rift Valley fever virusQ39946457
NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcriptionQ39960501
Safety and immunogenicity of a mutagenized, live attenuated Rift Valley fever vaccine, MP-12, in a Phase 1 dose escalation and route comparison study in humans.Q40124756
Comparative efficacy of two next-generation Rift Valley fever vaccinesQ40199478
Evaluation of lamb and calf responses to Rift Valley fever MP-12 vaccinationQ40206211
Evolutionary transition toward defective RNAs that are infectious by complementation.Q40213221
Synthesis, proteolytic processing and complex formation of N-terminally nested precursor proteins of the Rift Valley fever virus glycoproteinsQ40233812
Rescue of infectious rift valley fever virus entirely from cDNA, analysis of virus lacking the NSs gene, and expression of a foreign geneQ40311587
Genetic evidence for Rift Valley fever outbreaks in Madagascar resulting from virus introductions from the East African mainland rather than enzootic maintenanceQ40327417
Pathogenicity and neurovirulence of a mutagen-attenuated Rift Valley fever vaccine in rhesus monkeysQ40557158
Teratogenicity of a mutagenised Rift Valley fever virus (MVP 12) in sheep.Q40579610
Improved Recovery of Rabies Virus from Cloned cDNA Using a Vaccinia Virus‐Free Reverse Genetics SystemQ40629273
Immunogenicity of an inactivated Rift Valley fever vaccine in humans: a 12-year experience.Q40632227
Safety of a mutagen-attenuated Rift Valley fever virus vaccine in fetal and neonatal bovidsQ40645618
Safety and efficacy of a mutagen-attenuated Rift Valley fever virus vaccine in cattleQ40645625
Characterization of clone 13, a naturally attenuated avirulent isolate of Rift Valley fever virus, which is altered in the small segment.Q40679919
Ability of a mutagenized virus variant to protect young lambs from Rift Valley feverQ40753140
Further evaluation of a mutagen-attenuated Rift Valley fever vaccine in sheepQ40753243
Pathogenicity and immunogenicity of a mutagen-attenuated Rift Valley fever virus immunogen in pregnant ewesQ40795447
Mutagen-directed attenuation of Rift Valley fever virus as a method for vaccine developmentQ40814834
Regulatory considerations for emergency use of non-USDA licensed vaccines in the United States.Q42033084
Homologous recombination is apparent in infectious bursal disease virusQ43730394
Tempering the risk: Rift Valley fever and bioterrorismQ44936397
Characterization of a rare natural intertypic type 2/type 3 penta-recombinant vaccine-derived poliovirus isolated from a child with acute flaccid paralysis.Q48067438
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectRift Valley feverQ326638
Rift Valley fever virusQ14276794
Rift Valley fever phlebovirusQ24809101
P577publication date2017-07-17
P1433published inNPJ VaccinesQ30275609
P1476titleGenetic stability of Rift Valley fever virus MP-12 vaccine during serial passages in culture cells
P478volume2

Reverse relations

cites work (P2860)
Q92503441Evolution of Attenuation and Risk of Reversal in Peste des Petits Ruminants Vaccine Strain Nigeria 75/1
Q59351098Molecular aspects of Rift Valley fever virus and the emergence of reassortants
Q92812197Population- and Variant-Based Genome Analyses of Viruses from Vaccine-Derived Rabies Cases Demonstrate Product Specific Clusters and Unique Patterns

Search more.