Liquid chromatography-mass spectrometry method for the analysis of the anti-cancer agent capecitabine and its nucleoside metabolites in human plasma

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Liquid chromatography-mass spectrometry method for the analysis of the anti-cancer agent capecitabine and its nucleoside metabolites in human plasma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1570-0232(02)00674-8
P698PubMed publication ID12450548

P2093author name stringYan Xu
Jean L Grem
P2860cites workDesign of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissueQ27863454
Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabineQ33502454
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancerQ33855276
5-Fluorouracil: forty-plus and still ticking. A review of its preclinical and clinical developmentQ33925505
Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III studyQ34514696
Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III studyQ34519158
Randomized, open-label, phase II trial of oral capecitabine (Xeloda) vs. a reference arm of intravenous CMF (cyclophosphamide, methotrexate and 5-fluorouracil) as first-line therapy for advanced/metastatic breast cancerQ43791689
Influence of the antacid Maalox on the pharmacokinetics of capecitabine in cancer patientsQ74594881
P433issue1
P921main subjectcapecitabineQ420207
P304page(s)273-285
P577publication date2003-01-01
P1433published inJournal of Chromatography B Analytical Technologies in the Biomedical and Life SciencesQ2422407
P1476titleLiquid chromatography-mass spectrometry method for the analysis of the anti-cancer agent capecitabine and its nucleoside metabolites in human plasma
P478volume783

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cites work (P2860)
Q59136745A novel approach to the application of hexagonal mesoporous silica in solid-phase extraction of drugs
Q34398312A tolerability and pharmacokinetic study of adjuvant erlotinib and capecitabine with concurrent radiation in resected pancreatic cancer
Q47327071Development and optimization of locust bean gum and sodium alginate interpenetrating polymeric network of capecitabine
Q36904564Fixed-dose capecitabine is feasible: results from a pharmacokinetic and pharmacogenetic study in metastatic breast cancer
Q44604561Measurement of anti-cancer agent methoxyamine in plasma by tandem mass spectrometry with on-line sample extraction
Q37810210Quantification of Polar Drugs in Human Plasma with Liquid Chromatography–Tandem Mass Spectrometry
Q39568178The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC-MS.
Q35032865Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer
Q35212953Use of capecitabine in management of early colon cancer

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