Hyperbolic relationship between insulin secretion and sensitivity on oral glucose tolerance test

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Hyperbolic relationship between insulin secretion and sensitivity on oral glucose tolerance test is …
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scholarly articleQ13442814

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P356DOI10.1038/OBY.2008.307
P698PubMed publication ID18551118
P5875ResearchGate publication ID5306150

P50authorBernard ZinmanQ61337175
Anthony J HanleyQ89837571
P2093author name stringVladimir Vuksan
Ravi Retnakaran
Jill K Hamilton
Sandy Shen
P2860cites workHomeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in manQ26776977
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Accurate assessment of beta-cell function: the hyperbolic correctionQ34508795
The evolution of beta-cell dysfunction and insulin resistance in type 2 diabetesQ34655580
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetesQ35085591
Methods for clinical assessment of insulin sensitivity and beta-cell functionQ35214627
Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studiesQ35649213
Assessment of beta-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose testsQ36753104
Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucoseQ37006231
Insulin sensitivity and beta-cell function in women with polycystic ovary syndromeQ42522952
Oral glucose tolerance test indexes for insulin sensitivity and secretion based on various availabilities of sampling timesQ43584254
Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S.Q44043219
Meal and oral glucose tests for assessment of beta -cell function: modeling analysis in normal subjectsQ44185351
Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment in normal range weight and moderately obese type 2 diabetic patientsQ44526998
Validation of insulin sensitivity indices from oral glucose tolerance test parameters in obese children and adolescentsQ44786939
Evaluation of insulin release and insulin sensitivity through oral glucose tolerance test: differences between NGT, IFG, IGT, and type 2 diabetes mellitus. A cross-sectional and follow-up studyQ44956971
Adiponectin and beta cell dysfunction in gestational diabetes: pathophysiological implicationsQ46391592
Insulin sensitivity by oral glucose minimal models: validation against clampQ46598377
Two-hour seven-sample oral glucose tolerance test and meal protocol: minimal model assessment of beta-cell responsivity and insulin sensitivity in nondiabetic individualsQ46774753
Impact of differences in fasting glucose and glucose tolerance on the hyperbolic relationship between insulin sensitivity and insulin responsesQ46917186
Within-subject variability of measures of beta cell function derived from a 2 h OGTT: implications for research studiesQ46956144
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone.Q51484788
Preventing type 2 diabetes using combination therapy: design and methods of the CAnadian Normoglycaemia Outcomes Evaluation (CANOE) trial.Q51492013
Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test.Q51551670
Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies.Q51558724
Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.Q51561183
The relation of proinsulin and insulin to insulin sensitivity and acute insulin response in subjects with newly diagnosed type II diabetes: the Insulin Resistance Atherosclerosis Study.Q51561681
Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion.Q51596078
Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.Q51598262
Population approaches to estimate minimal model indexes of insulin sensitivity and glucose effectiveness using full and reduced sampling schedules.Q51933971
Fitting straight lines when both variables are subject to errorQ52795595
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectglycobiologyQ899224
preproinsulinQ7240673
glucoseQ37525
P304page(s)1901-1907
P577publication date2008-06-12
P1433published inObesityQ15763232
P1476titleHyperbolic relationship between insulin secretion and sensitivity on oral glucose tolerance test
P478volume16

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