Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity

scientific article published in November 1997

Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-2999(97)81924-3
P698PubMed publication ID9424015

P2093author name stringL S Harris
M D Aceto
E R Bowman
P2860cites workActions of etorphine hydrochloride, (M99): a potent morphine-like agentQ28364330
Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatmentQ33782677
Novel analgesics and molecular rearrangements in the morphine-thebaine group. III. Alcohols of the 6,14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and -norcodeineQ34054548
Possible role of distinct morphine and enkephalin receptors in mediating actins of benzomorphan drugs (putative kappa and sigma agonists)Q36400557
Caffeine elicited withdrawal signs in morphine-dependent rhesus monkeysQ40171073
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor geneQ41157124
The Effects of Naloxone and Nalorphine during the Development of Morphine Dependence in Rhesus MonkeysQ41232421
After chronic opioid exposure sensory neurons become supersensitive to the excitatory effects of opioid agonists and antagonists as occurs after acute elevation of GM1 gangliosideQ44331421
Chronic selective activation of excitatory opioid receptor functions in sensory neurons results in opioid 'dependence' without toleranceQ44332228
Opioid receptor interaction and adenylyl cyclase inhibition of dihydroetorphine: direct comparison with etorphineQ44334917
Specific N- or C-terminus modified dynorphin and beta-endorphin peptides can selectively block excitatory opioid receptor functions in sensory neurons and unmask potent inhibitory effects of opioid agonistsQ44335084
Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependenceQ44337423
Dual regulation by mu, delta and kappa opioid receptor agonists of K+ conductance of DRG neurons and neuroblastoma X DRG neuron hybrid F11 cellsQ44341255
Etorphine elicits anomalous excitatory opioid effects on sensory neurons treated with GM1 ganglioside or pertussis toxin in contrast to its potent inhibitory effects on naive or chronic morphine-treated cellsQ44344759
Characterization of opioid receptors in nervous tissueQ44352061
In vivo opiate receptor binding of oripavines to mu, delta and kappa sites in rat brain as determined by an ex vivo labeling methodQ45719813
The binding spectrum of narcotic analgesic drugs with different agonist and antagonist propertiesQ46698394
Unidirectional non-cross-tolerance (UNCT) in rats and an apparent dissociation between narcotic tolerance and physical dependenceQ48520800
3H-etorphine and 3H-diprenorphine receptor binding in vitro and in vivo: differential effect of Na+ and guanylyl imidodiphosphateQ48884024
Etorphine in man. I. Subjective effects and suppression of morphine abstinenceQ51300051
The biological, social and clinical bases of drug addiction: commentary and debate.Q52274270
Dihydroetorphine, a potent opioid with low dependent potentialQ63244978
Dihydroetorphine is a mu-receptor-selective ligandQ70956088
Antinociceptive effect of dihydroetorphine in diabetic miceQ72296911
Antinociceptive effect of dihydroetorphine and its tolerance/dependence liability in miceQ72556401
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectopioidQ427523
physical dependenceQ2622112
P304page(s)215-223
P577publication date1997-11-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleEtorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity
P478volume338

Reverse relations

cites work (P2860)
Q38975808Analgesic activity of Eugenia jambolana leave constituent: a dikaempferol rhamnopyranoside from ethyl acetate soluble fraction
Q34477079Anti-allodynic actions of intravenous opioids in the nerve injured rat: potential utility of heroin and dihydroetorphine against neuropathic pain.
Q44000148Biochemical characterisation of newly developed beta-etorphine and beta-dihydroetorphine derivatives
Q41881067Central Antinociceptive and Mechanism of Action of Pereskia bleo Kunth Leaves Crude Extract, Fractions, and Isolated Compounds
Q41134315Cinnamoyl derivatives of 7alpha-aminomethyl-6,14-endo-ethanotetrahydrothebaine and 7alpha-aminomethyl-6,14-endo-ethanotetrahydrooripavine and related opioid ligands
Q34164632Dihydroetorphine: a potent analgesic: pharmacology, toxicology, pharmacokinetics, and clinical effects
Q44867443Dihydroetorphine: physical dependence and stereotypy after continuous infusion in the rat.
Q44911815Dose, duration, and pattern of nicotine administration as determinants of behavioral dependence in rats
Q43070514Endogenous opiates: 1997.
Q34001543Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor
Q41874430Mixed kappa/mu opioid receptor agonists: the 6 beta-naltrexamines.
Q44350368Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GM1 ganglioside-regulated opioid receptor functions
Q36822435Orvinols with mixed kappa/mu opioid receptor agonist activity
Q33566172Pharmacological mechanisms underlying the antinociceptive and tolerance effects of the 6,14-bridged oripavine compound 030418
Q34363972Pharmacological studies with a nonpeptidic, delta-opioid (-)-(1R,5R,9R)-5,9-dimethyl-2'-hydroxy-2-(6-hydroxyhexyl)-6,7-benzomorphan hydrochloride ((-)-NIH 11082).
Q36170816Quinoline Alkaloids Isolated from Choisya Aztec-Pearl and Their Contribution to the Overall Antinociceptive Activity of This Plant.
Q39671329Structural determinants of opioid activity in derivatives of 14-aminomorphinones: effect of substitution in the aromatic ring of cinnamoylaminomorphinones and codeinones
Q34063774The discriminative stimulus effects of mecamylamine in nicotine-treated and untreated rhesus monkeys

Search more.