Multiple epithelial Na+ channel domains participate in subunit assembly

scientific article published on 27 May 2003

Multiple epithelial Na+ channel domains participate in subunit assembly is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPRENAL.00095.2003
P698PubMed publication ID12770839
P5875ResearchGate publication ID10739342

P50authorShaohu ShengQ42108894
P2093author name stringThomas R Kleyman
Rebecca P Hughey
Baofeng Hu
James B Bruns
Yoon J Ahn
P2860cites workA novel splice-site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 familiesQ24313454
A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channelQ24315886
Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation stateQ24548387
Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel geneQ24562174
Permeability properties of ENaC selectivity filter mutantsQ24655070
Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factorsQ28217348
Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channelQ28240272
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunitsQ28249570
Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1Q28275138
Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndromeQ28288744
Membrane topology of the epithelial sodium channel in intact cellsQ28304845
Trafficking and cell surface stability of the epithelial Na+ channel expressed in epithelial Madin-Darby canine kidney cellsQ28570229
The NH(2) terminus of the epithelial sodium channel contains an endocytic motifQ30808775
Charged residues in the M2 region of alpha-hENaC play a role in channel conductanceQ30837681
Epithelial sodium channel pore region. structure and role in gating.Q31449663
gamma -glutamyltransferase and its isoform mediate an endoplasmic reticulum stress response.Q31695639
Two sporadic cases of Liddle's syndrome caused by De novo ENaC mutationsQ32066994
Early aldosterone action: toward filling the gap between transcription and transportQ33731974
Functional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channelsQ33764301
The heterotetrameric architecture of the epithelial sodium channel (ENaC).Q33888043
Point mutations in alpha bENaC regulate channel gating, ion selectivity, and sensitivity to amilorideQ33915250
Assembly of ROMK1 (Kir 1.1a) inward rectifier K+ channel subunits involves multiple interaction sitesQ34167570
Helical membrane proteins: diversity of functions in the context of simple architectureQ34282445
Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processingQ34286224
Trafficking and cell surface stability of ENaC.Q34335739
New ideas about aldosterone signaling in epitheliaQ34552939
Mechanisms of aldosterone's action on epithelial Na + transport.Q34561327
The epithelial Na+ channel: cell surface insertion and retrieval in Na+ homeostasis and hypertensionQ34594423
Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.Q34711250
Internal packing of helical membrane proteinsQ35749292
Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channelQ35974594
Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathwaysQ36301546
Identification of amino acid residues in the alpha, beta, and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeationQ36411832
On the molecular basis of ion permeation in the epithelial Na+ channelQ36436809
Gating induces a conformational change in the outer vestibule of ENaCQ36440897
Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cellsQ36445128
A single point mutation in the pore region of the epithelial Na+ channel changes ion selectivity by modifying molecular sieving.Q36461173
Non-coordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditionsQ40856181
Recombinant protein synthesis in Chinese hamster ovary cells using a vaccinia virus/bacteriophage T7 hybrid expression systemQ41185196
Cell surface expression and biosynthesis of epithelial Na+ channelsQ41876264
Regions in the carboxy terminus of alpha-bENaC involved in gating and functional effects of actinQ42651917
External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probabilityQ42686470
Helix-helix packing and interfacial pairwise interactions of residues in membrane proteinsQ43716829
Second transmembrane domains of ENaC subunits contribute to ion permeation and selectivityQ43743310
A novel mutation of the epithelial Na+ channel causes type 1 pseudohypoaldosteronism.Q44177359
Asymmetric organization of the pore region of the epithelial sodium channelQ44308467
Antibody affinity—III the role of multivalenceQ45194037
Characterization of the selectivity filter of the epithelial sodium channelQ48896218
The second hydrophobic domain contributes to the kinetic properties of epithelial sodium channelsQ48904037
Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surfaceQ48925095
Subunit stoichiometry of the epithelial sodium channelQ48939958
Interactions between subunits of the human epithelial sodium channel.Q48951272
Identification of an amiloride binding domain within the alpha-subunit of the epithelial Na+ channel.Q48952850
Molecular determinants for assembly of G-protein-activated inwardly rectifying K+ channelsQ48959299
Inhibitory interactions between two inward rectifier K+ channel subunits mediated by the transmembrane domainsQ49016947
A pore segment in DEG/ENaC Na(+) channels.Q50516655
Voltage-gated K+ channels contain multiple intersubunit association sites.Q50760550
P433issue4
P304page(s)F600-9
P577publication date2003-05-27
P1433published inAmerican Journal of Physiology - Renal PhysiologyQ2610177
P1476titleMultiple epithelial Na+ channel domains participate in subunit assembly
P478volume285

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cites work (P2860)
Q33944049A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones
Q39955492AICAR activates AMPK and alters PIP2 association with the epithelial sodium channel ENaC to inhibit Na+ transport in H441 lung epithelial cells
Q34155244Cys Palmitoylation of the β Subunit Modulates Gating of the Epithelial Sodium Channel
Q33619575Cysteine palmitoylation of the γ subunit has a dominant role in modulating activity of the epithelial sodium channel
Q44710654Extracellular histidine residues crucial for Na+ self-inhibition of epithelial Na+ channels
Q35169656Human heart failure is associated with abnormal C-terminal splicing variants in the cardiac sodium channel
Q28296575Role of the ubiquitin system in regulating ion transport
Q36614544Small heat shock protein alphaA-crystallin regulates epithelial sodium channel expression