Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis.

scientific article published on 29 May 2003

Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis. is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M305399200
P8608Fatcat IDrelease_775fcckqszbtznnknrhv7ir2am
P698PubMed publication ID12777390
P5875ResearchGate publication ID10734405

P50authorSamuel H. WilsonQ62027988
P2093author name stringRoger Woodgate
Thomas A Kunkel
David D Shock
Rajendra Prasad
William A Beard
Katarzyna Bebenek
Esther Hou
P2860cites workEvidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reactionQ71144441
The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesisQ72994394
Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repairQ73357816
Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanismQ74615796
hRAD30 mutations in the variant form of xeroderma pigmentosumQ22010237
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.Q24537708
Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iotaQ24597750
Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamilyQ24673479
Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, PoletaQ27935465
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase etaQ28115711
Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase etaQ28116380
The Y-family of DNA polymerasesQ29615308
Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesionsQ29619958
The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replicationQ31422789
DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational changeQ31452230
A plethora of lesion-replicating DNA polymerasesQ33732359
5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitroQ33938237
Human DNA polymerase iota promiscuous mismatch extensionQ33950961
Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.Q34157224
Structural Insights into the Origins of DNA Polymerase FidelityQ35123987
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.Q35588920
Compilation and alignment of DNA polymerase sequencesQ35774285
The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidanceQ36099918
Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA.Q36182449
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein.Q36275662
Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase beta by mass spectrometryQ38313808
Substrate binding by human apurinic/apyrimidinic endonuclease indicates a Briggs-Haldane mechanismQ38349374
Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iotaQ39455619
Compilation, alignment, and phylogenetic relationships of DNA polymerasesQ40405362
Requirement of mammalian DNA polymerase-beta in base-excision repair.Q41239890
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesisQ41734679
Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity.Q43833668
Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA GlycosylaseQ57942555
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectproteolysisQ33123
P304page(s)29649-29654
P577publication date2003-05-29
P1433published inJournal of Biological ChemistryQ867727
P1476titleLocalization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis
P478volume278