Immunodeficiency viruses. Not enough sans Nef.

scientific article

Immunodeficiency viruses. Not enough sans Nef. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S0960-9822(00)00135-4
P698PubMed publication ID7953537

P2093author name stringLittman DR
P2860cites workSerine phosphorylation-independent downregulation of cell-surface CD4 by nefQ22251290
Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domainQ24336240
Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytesQ24564842
Importance of the nef gene for maintenance of high virus loads and for development of AIDSQ29618369
Protective effects of a live attenuated SIV vaccine with a deletion in the nef geneQ33196552
Altered T cell activation and development in transgenic mice expressing the HIV-1 nef geneQ34043731
CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.Q34064274
The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophagesQ36362652
Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgeneQ36362819
Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicityQ36633938
Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivoQ36650992
Disruption of the CD4-p56lck complex is required for rapid internalization of CD4Q37154861
Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptorQ41613228
The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.Q41768724
Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sortingQ42805965
Natural HIV-1 NEF accelerates virus replication in primary human lymphocytesQ45866982
P433issue7
P407language of work or nameEnglishQ1860
P1104number of pages3
P304page(s)618-620
P577publication date1994-07-01
P1433published inCurrent BiologyQ1144851
P1476titleImmunodeficiency viruses. Not enough sans Nef.
P478volume4

Reverse relations

cites work (P2860)
Q41176259Apoptosis: pathophysiology of programmed cell death
Q34092864Distinct chemokine triggers and in vivo migratory paths of fluorescein dye-labeled T Lymphocytes in acutely simian immunodeficiency virus SIVmac251-infected and uninfected macaques
Q39792146Hidden messages in the nef gene of human immunodeficiency virus type 1 suggest a novel RNA secondary structure
Q41096686Human immunodeficiency virus infection of human cells transplanted to severe combined immunodeficient mice.
Q35847908Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV
Q35845424Myxoma virus induces extensive CD4 downregulation and dissociation of p56lck in infected rabbit CD4+ T lymphocytes
Q24322710The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling
Q41338297Towards a consensus for a role of Nef in both viral replication and immunomodulation?

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