The neuroprotective effect of overexpression of calbindin-D(28k) in an animal model of Parkinson's disease

scientific article published on 25 August 2012

The neuroprotective effect of overexpression of calbindin-D(28k) in an animal model of Parkinson's disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12035-012-8332-3
P698PubMed publication ID22923348

P2093author name stringYu-Hua Zhu
Xiao-Rong Zhu
Hong-Hua Yuan
Ren-Jin Chen
Chang-Ling Peng
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blockedQ24318845
Mapping of a gene for Parkinson's disease to chromosome 4q21-q23Q28295005
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosisQ29614983
Calcium-binding proteins in the nervous systemQ35342133
Don't get too excited: mechanisms of glutamate-mediated Purkinje cell deathQ36015270
Calbindin-D28K prevents drug-induced dopaminergic neuronal death by inhibiting caspase and calpain activityQ39991930
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's diseaseQ40846012
Calbindin-D28k is expressed in osteoblastic cells and suppresses their apoptosis by inhibiting caspase-3 activityQ40876368
Calbindin-D28K-containing neurons in animal models of neurodegeneration: possible protection from excitotoxicityQ42451229
First Parkinson gene therapy trial launchesQ45869161
In vitro enzyme activation with calbindin‐D28k, the vitamin D‐dependent 28 kDa calcium binding proteinQ48530701
Dopaminergic neurons expressing calbindin in normal and parkinsonian monkeysQ48650819
Vulnerability of midbrain dopaminergic neurons in calbindin-D28k-deficient mice: lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver miceQ48806960
Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K.Q48899006
The neurotoxin MPTP increases calbindin-D28k levels in mouse midbrain dopaminergic neuronsQ49067381
P433issue1
P921main subjectParkinson's diseaseQ11085
overexpressionQ61643320
P304page(s)117-122
P577publication date2012-08-25
P1433published inMolecular NeurobiologyQ15716645
P1476titleThe neuroprotective effect of overexpression of calbindin-D(28k) in an animal model of Parkinson's disease
P478volume47

Reverse relations

cites work (P2860)
Q104064567An updated investigation on the dromedary camel cerebellum (Camelus dromedarius) with special insight into the distribution of calcium-binding proteins
Q92891422Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP+-induced neuronal death
Q30277098Calbindin Knockout Alters Sex-Specific Regulation of Behavior and Gene Expression in Amygdala and Prefrontal Cortex
Q41674970Calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques
Q92285021Calbindin-D28K Limits Dopamine Release in Ventral but Not Dorsal Striatum by Regulating Ca2+ Availability and Dopamine Transporter Function
Q45852337Calbindin-D28K immunoreactivity in the human cerebellar cortex
Q38598375Chronic MPTP administration regimen in monkeys: a model of dopaminergic and non-dopaminergic cell loss in Parkinson's disease
Q41443944Comparison of immunoreactivities of calbindin-D28k, calretinin and parvalbumin in the striatum between young, adult and aged mice, rats and gerbils
Q27302860Drosophila Cbp53E Regulates Axon Growth at the Neuromuscular Junction
Q31060511Hippocampal α-synuclein and interneurons in Parkinson's disease: Data from human and mouse models
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Q38826152Neurochemistry of the Anterior Thalamic Nuclei
Q30426322Paternal deprivation affects the functional maturation of corticotropin-releasing hormone (CRH)- and calbindin-D28k-expressing neurons in the bed nucleus of the stria terminalis (BNST) of the biparental Octodon degus
Q30844860Quantitative proteomic analysis of Parkin substrates in Drosophila neurons.
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Q39281423The role of Ca2+ signaling in Parkinson's disease
Q64077797Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

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