review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Roger Chung | Q53110401 |
Fleur McLeary | Q63365244 | ||
Rowan Radford | Q63890163 | ||
Peter Faller | Q50036921 | ||
P2093 | author name string | Dean L Pountney | |
Michael Goulding | |||
Alexandre N Rcom-H'cheo-Gauthier | |||
Yuho Okita | |||
P2860 | cites work | Association of metallothionein-III with oligodendroglial cytoplasmic inclusions in multiple system atrophy | Q24293470 |
Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease | Q28391762 | ||
Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain | Q28575311 | ||
A faulty interaction between SOD1 and hCCS in neurodegenerative disease | Q28828156 | ||
Epidemiology of Parkinson's disease. | Q30238651 | ||
Synergistic cellular responses to heavy metal exposure: A minireview | Q88308204 | ||
Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress | Q88511743 | ||
The genetics of Parkinson disease | Q89758290 | ||
Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases | Q90749951 | ||
Non-coordinative metal selectivity bias in human metallothioneins metal-thiolate clusters | Q93020367 | ||
Epidemiology of Parkinson Disease | Q30244735 | ||
Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice. | Q30494594 | ||
Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson's disease | Q33767295 | ||
Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease | Q33776138 | ||
The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen | Q33790013 | ||
Mammalian Metallothionein-3: New Functional and Structural Insights | Q33838378 | ||
New evidence on iron, copper accumulation and zinc depletion and its correlation with DNA integrity in aging human brain regions | Q34082641 | ||
The clinical symptoms of Parkinson's disease | Q34533843 | ||
Chemistry and biology of mammalian metallothioneins. | Q34629949 | ||
Calmodulin as a direct detector of Ca2+ signals | Q34673083 | ||
Network dysfunction in α-synuclein transgenic mice and human Lewy body dementia | Q36410380 | ||
Ceruloplasmin and what it might do. | Q36779523 | ||
Function and regulation of human copper-transporting ATPases | Q36872228 | ||
Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons | Q36928454 | ||
Aging results in copper accumulations in glial fibrillary acidic protein-positive cells in the subventricular zone | Q37170411 | ||
Copper transport to the brain by the blood-brain barrier and blood-CSF barrier | Q37181841 | ||
Cellular distribution of copper to superoxide dismutase involves scaffolding by membranes | Q37409241 | ||
Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels | Q37514445 | ||
Copper and copper proteins in Parkinson's disease | Q37616391 | ||
Pooled analysis of iron-related genes in Parkinson's disease: association with transferrin | Q37671088 | ||
Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies. | Q37737068 | ||
Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain. | Q37766269 | ||
Molecular mechanisms of regeneration in Alzheimer's disease brain | Q37768851 | ||
Metalloproteomics and metal toxicology of α-synuclein | Q37808957 | ||
Glia: initiators and progressors of pathology in Parkinson's disease | Q37842235 | ||
Neuroprotection and regeneration by extracellular metallothionein via lipoprotein-receptor-related proteins. | Q37903764 | ||
Raised calcium and oxidative stress cooperatively promote alpha-synuclein aggregate formation | Q38060447 | ||
Roles and therapeutic potential of metallothioneins in neurodegenerative diseases. | Q38099352 | ||
Bioinorganic Chemistry of Parkinson's Disease: Affinity and Structural Features of Cu(I) Binding to the Full-Length β-Synuclein Protein. | Q38618629 | ||
Calcipotriol inhibits α-synuclein aggregation in SH-SY5Y neuroblastoma cells by a Calbindin-D28k-dependent mechanism | Q38717826 | ||
Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics | Q38766440 | ||
Amyotrophic lateral sclerosis-like superoxide dismutase 1 proteinopathy is associated with neuronal loss in Parkinson's disease brain | Q38773599 | ||
Alpha-synuclein and beta-amyloid - different targets, same players: calcium, free radicals and mitochondria in the mechanism of neurodegeneration | Q38912045 | ||
Calcium and Parkinson's disease | Q38945252 | ||
Cytosolic iron chaperones: Proteins delivering iron cofactors in the cytosol of mammalian cells. | Q50944156 | ||
Non-ceruloplasmin bound copper and ATP7B gene variants in Alzheimer's disease. | Q51587028 | ||
Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation. | Q51732455 | ||
Brain iron and ferritin in Parkinson's and Alzheimer's diseases. | Q53184175 | ||
Up-regulation of metallothionein gene expression in parkinsonian astrocytes. | Q54356779 | ||
Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration | Q57666825 | ||
Model Senescent Microglia Induce Disease Related Changes in α-Synuclein Expression and Activity | Q58804178 | ||
Extracellular Interactions of Alpha-Synuclein in Multiple System Atrophy | Q60947930 | ||
Accumulation of copper and other metal ions, and metallothionein I/II expression in the bovine brain as a function of aging | Q60955728 | ||
Neurite Collapse and Altered ER Ca Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation | Q61454783 | ||
Recruitment of calbindin into nigral dopamine neurons protects against MPTP-Induced parkinsonism | Q64376686 | ||
Parkinson's disease: a short story of 200 years | Q64791337 | ||
A Proposed Mechanism for Neurodegeneration in Movement Disorders Characterized by Metal Dyshomeostasis and Oxidative Stress | Q64868269 | ||
Raised cerebrospinal-fluid copper concentration in Parkinson's disease | Q69903302 | ||
Ceruloplasmin oxidation, a feature of Parkinson's disease CSF, inhibits ferroxidase activity and promotes cellular iron retention | Q82968961 | ||
Calcium: Alpha-Synuclein Interactions in Alpha-Synucleinopathies | Q39075636 | ||
Potential Modes of Intercellular α-Synuclein Transmission | Q39152836 | ||
Alpha-synuclein aggregates are excluded from calbindin-D28k-positive neurons in dementia with Lewy bodies and a unilateral rotenone mouse model | Q39286106 | ||
Iron transport proteins: Gateways of cellular and systemic iron homeostasis | Q39374086 | ||
alpha-Synuclein modulation of Ca2+ signaling in human neuroblastoma (SH-SY5Y) cells | Q39782960 | ||
Human metallothionein gene expression is upregulated by beta-thujaplicin: possible involvement of protein kinase C and reactive oxygen species | Q40333665 | ||
Meis1 promotes poly (rC)-binding protein 2 expression and inhibits angiotensin II-induced cardiomyocyte hypertrophy | Q41103735 | ||
Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells | Q41843416 | ||
The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson's disease | Q42351555 | ||
α-Synuclein impairs ferritinophagy in the retinal pigment epithelium: Implications for retinal iron dyshomeostasis in Parkinson's disease | Q42373959 | ||
Age-related changes in calbindin-D28k, calretinin, and parvalbumin-immunoreactive neurons in the human cerebral cortex | Q42443528 | ||
Reduced ferroxidase activity in the cerebrospinal fluid from patients with Parkinson's disease | Q42472074 | ||
Adrenergic nerves compensate for a decline in calcium buffering during ageing. | Q42495049 | ||
Three functional facets of calbindin D-28k | Q42581477 | ||
Metallothioneins I/II are involved in the neuroprotective effect of sildenafil in focal brain injury. | Q44008754 | ||
Copper pathology in vulnerable brain regions in Parkinson's disease | Q44278519 | ||
The neuroprotective effect of overexpression of calbindin-D(28k) in an animal model of Parkinson's disease | Q44563974 | ||
Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease. | Q46009075 | ||
Chemistry of mammalian metallothioneins and their interaction with amyloidogenic peptides and proteins | Q46266209 | ||
α-Synuclein-Dependent Calcium Entry Underlies Differential Sensitivity of Cultured SN and VTA Dopaminergic Neurons to a Parkinsonian Neurotoxin. | Q47135899 | ||
A low blood copper concentration is a co-morbidity burden factor in Parkinson's disease development | Q47333037 | ||
Accumulation of dysfunctional SOD1 protein in Parkinson's disease is not associated with mutations in the SOD1 gene. | Q47593429 | ||
Dexamethasone Inhibits Copper-Induced Alpha-Synuclein Aggregation by a Metallothionein-Dependent Mechanism | Q47611418 | ||
Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain. | Q47614352 | ||
Iron promotes α-synuclein aggregation and transmission by inhibiting TFEB-mediated autophagosome-lysosome fusion | Q47648956 | ||
Astroglial and microglial contributions to iron metabolism disturbance in Parkinson's disease | Q47873659 | ||
Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL. | Q47948873 | ||
Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons. | Q48266120 | ||
Clinical utility of copper, ceruloplasmin, and metallothionein plasma determinations in human neurodegenerative patients and their first-degree relatives | Q48372462 | ||
Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression | Q48405912 | ||
Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees | Q48514121 | ||
A novel glycosylphosphatidylinositol-anchored form of ceruloplasmin is expressed by mammalian astrocytes | Q48638438 | ||
Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K. | Q48899006 | ||
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction | Q49829897 | ||
Genetics of Parkinson disease | Q50081370 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Parkinson's disease | Q11085 |
alpha-synuclein | Q24725459 | ||
metal | Q11426 | ||
Parkinson’s Disease | Q39074077 | ||
P304 | page(s) | 179 | |
P577 | publication date | 2019-02-19 | |
P1433 | published in | Cells | Q27724621 |
P1476 | title | Switching on Endogenous Metal Binding Proteins in Parkinson's Disease | |
P478 | volume | 8 |
Q90319955 | Differential effects of Cu2+ and Fe3+ ions on in vitro amyloid formation of biologically-relevant α-synuclein variants |
Q91962671 | Genetic Disorders Associated with Metal Metabolism |
Q92028537 | Metal Chelation Therapy and Parkinson's Disease: A Critical Review on the Thermodynamics of Complex Formation between Relevant Metal Ions and Promising or Established Drugs |
Q99635876 | The relationships of vitamin D, vitamin D receptor gene polymorphisms, and vitamin D supplementation with Parkinson's disease |
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