Multiple domains of TonEBP cooperate to stimulate transcription in response to hypertonicity.

scientific article published on 11 September 2003

Multiple domains of TonEBP cooperate to stimulate transcription in response to hypertonicity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M308795200
P698PubMed publication ID12970349

P50authorEmanuela CollaQ48297708
P2093author name stringSang Do Lee
Ki Young Na
Mee Rie Sheen
H Moo Kwon
P2860cites workTonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicityQ22008847
NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and JunQ22010152
Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stressQ24291525
Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factorQ24292112
Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genesQ24323167
Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentrationQ24530428
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteinsQ27861094
The NFAT-related protein NFATL1 (TonEBP/NFAT5) is induced upon T cell activation in a calcineurin-dependent mannerQ28142037
Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP)Q28204983
The role of NFAT transcription factors in integrin-mediated carcinoma invasionQ28206477
Mouse TonEBP-NFAT5: expression in early development and alternative splicingQ28588125
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300Q28619230
Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cellsQ34117766
Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseasesQ34133850
cAMP-independent role of PKA in tonicity-induced transactivation of tonicity-responsive enhancer/ osmotic response element-binding proteinQ34429978
TonEBP transcriptional activator in the cellular response to increased osmolalityQ34795046
Evolutionary relationships among Rel domains indicate functional diversification by recombinationQ35893955
TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicityQ39675201
Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicityQ40763558
The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expressionQ40854151
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivatorQ41133317
Transcriptional activation modulated by homopolymeric glutamine and proline stretchesQ41488003
The osmoprotective function of the NFAT5 transcription factor in T cell development and activationQ46040663
A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in DrosophilaQ46088826
A P-insertion screen identifying novel X-linked essential genes in Drosophila.Q52126589
P433issue48
P407language of work or nameEnglishQ1860
P304page(s)47571-47577
P577publication date2003-09-11
P1433published inJournal of Biological ChemistryQ867727
P1476titleMultiple domains of TonEBP cooperate to stimulate transcription in response to hypertonicity
P478volume278

Reverse relations

cites work (P2860)
Q34297089Arterial wall stress controls NFAT5 activity in vascular smooth muscle cells
Q92867402Co-expression of glycosylated aquaporin-1 and transcription factor NFAT5 contributes to aortic stiffness in diabetic and atherosclerosis-prone mice
Q40149475Downregulation of renal TonEBP in hypokalemic rats.
Q39882455EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions
Q36464964Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletal muscle
Q33502710Exclusion of NFAT5 from mitotic chromatin resets its nucleo-cytoplasmic distribution in interphase
Q35323760Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBP
Q36700599Hyperosmotic stress response: comparison with other cellular stresses
Q37512897Hypertonic stress in the kidney: a necessary evil
Q40446310Increased reactive oxygen species contribute to high NaCl-induced activation of the osmoregulatory transcription factor TonEBP/OREBP.
Q28257538Intracellular water homeostasis and the mammalian cellular osmotic stress response
Q36841546LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding
Q47266408Maturation of TonEBP expression in developing rat kidney
Q46816792Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP.
Q33776462Modulation of TonEBP activity by SUMO modification in response to hypertonicity
Q58712591NFAT5 Isoform C Controls Biomechanical Stress Responses of Vascular Smooth Muscle Cells
Q36847032NFAT5 in cellular adaptation to hypertonic stress - regulations and functional significance
Q36825529Novel nuclear localization signal regulated by ambient tonicity in vertebrates
Q30424684Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation
Q37737105Osmolality/salinity-responsive enhancers (OSREs) control induction of osmoprotective genes in euryhaline fish
Q35903567Osmotic regulation of renal betaine transport: transcription and beyond
Q39143253Phosphorylation by casein kinase 1 regulates tonicity-induced osmotic response element-binding protein/tonicity enhancer-binding protein nucleocytoplasmic trafficking
Q33756637Rapid hyperosmotic coinduction of two tilapia (Oreochromis mossambicus) transcription factors in gill cells
Q64069932Regulation of Inflammatory Functions of Macrophages and T Lymphocytes by NFAT5
Q50726607Regulation of nucleocytoplasmic trafficking of transcription factor OREBP/TonEBP/NFAT5.
Q34528825Survival in hostile environments: strategies of renal medullary cells
Q90208774The evolving role of TonEBP as an immunometabolic stress protein
Q40371037TonEBP is inhibited by RNA helicase A via interaction involving the E'F loop.
Q41763624TonEBP/NFAT5 regulates ACTBL2 expression in biomechanically activated vascular smooth muscle cells
Q40079647Tonicity-regulated gene expression
Q81309595Transcriptional activator TonE-binding protein in cellular protection and differentiation
Q39827641Urea promotes TonEBP expression and cellular adaptation in extreme hypertonicity

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