Synthesis, biodistribution and micro-PET imaging of a potential cancer biomarker carbon-11 labeled MMP inhibitor (2R)-2-[[4-(6-fluorohex-1-ynyl)phenyl]sulfonylamino]-3-methylbutyric acid [11C]methyl ester

scientific article published on October 1, 2003

Synthesis, biodistribution and micro-PET imaging of a potential cancer biomarker carbon-11 labeled MMP inhibitor (2R)-2-[[4-(6-fluorohex-1-ynyl)phenyl]sulfonylamino]-3-methylbutyric acid [11C]methyl ester is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0969-8051(03)00086-6
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0969805103000866?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0969805103000866?httpAccept=text/xml
P698PubMed publication ID14499334
P5875ResearchGate publication ID9089758

P50authorGeorge SledgeQ92594250
Kathy D. MillerQ91794468
P2093author name stringJi-Quan Wang
Qi-Huang Zheng
Xiangshu Fei
Timothy R. DeGrado
Gary D. Hutchins
George W. Sledge
Michael L. Sullivan
Bruce H. Mock
Barbara E. Glick-Wilson
K. Lee Stone
Tanya D. Martinez
Dawn J. Gay
Winston L. Baity
P2860cites workStructure-activity relationships and pharmacokinetic analysis for a series of potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitorsQ28369255
Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applicationsQ33692926
Matrix metalloproteinases in tumour invasion and metastasisQ33765792
In vivo molecular target assessment of matrix metalloproteinase inhibitionQ33949202
[11C]Choline as a potential PET marker for imaging of breast cancer athymic miceQ44230675
Tumor detection using 18F-labeled matrix metalloproteinase-2 inhibitorQ44353059
Synthesis of radiolabeled biphenylsulfonamide matrix metalloproteinase inhibitors as new potential PET cancer imaging agentsQ44472706
Synthesis, biodistribution and micro-PET imaging of a potential cancer biomarker carbon-11 labeled MMP inhibitor (2R)-2-[[4-(6-fluorohex-1-ynyl)phenyl]sulfonylamino]-3-methylbutyric acid [11C]methyl esterQ44589894
Improved synthesis of beta-CIT and [11C]beta-CIT labeled at nitrogen or oxygen positions.Q51557600
Synthesis and preliminary biological evaluation of MMP inhibitor radiotracers [11C]methyl-halo-CGS 27023A analogs, new potential PET breast cancer imaging agents.Q53668849
A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridinesQ56028298
Carbonic Anhydrase and Matrix Metalloproteinase Inhibitors: Sulfonylated Amino Acid Hydroxamates with MMP Inhibitory Properties Act as Efficient Inhibitors of CA Isozymes I, II, and IV, andN-Hydroxysulfonamides Inhibit Both These Zinc Enzymes1Q58863326
A simple synthesis of [11C]methyl triflateQ67507426
Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbitsQ73589806
Reduced angiogenesis and tumor progression in gelatinase A-deficient miceQ74309789
Sulfonamide-based hydroxamic acids as potent inhibitors of mouse macrophage metalloelastaseQ77743801
Convenient gas phase bromination of [11C]methane and production of [11C]methyl triflateQ77925202
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
molecular medicineQ3523816
P304page(s)753-760
P577publication date2003-10-01
P1433published inNuclear Medicine and BiologyQ7067979
P1476titleSynthesis, biodistribution and micro-PET imaging of a potential cancer biomarker carbon-11 labeled MMP inhibitor (2R)-2-[[4-(6-fluorohex-1-ynyl)phenyl]sulfonylamino]-3-methylbutyric acid [11C]methyl ester
P478volume30

Reverse relations

cites work (P2860)
Q38202093A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging
Q92816934Active-Site Targeting Paramagnetic Probe for Matrix Metalloproteinases
Q37139413Clinical biomarkers of angiogenesis inhibition
Q37626064Imaging aspects of the tumor stroma with therapeutic implications
Q37236103Interrogating tumor metabolism and tumor microenvironments using molecular positron emission tomography imaging. Theranostic approaches to improve therapeutics
Q37687929Mechanism-based profiling of MMPs.
Q92702708Molecular Imaging Probes Based on Matrix Metalloproteinase Inhibitors (MMPIs)
Q37710417Molecular Imaging of Proteases in Cancer
Q34496670Molecular imaging in cancer treatment
Q58816167Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo
Q38000174Non-FDG imaging of atherosclerosis: will imaging of MMPs assess plaque vulnerability?
Q37366243PET Imaging of Angiogenesis
Q36777285Positron emission tomography tracers for imaging angiogenesis
Q30475818Preclinical molecular imaging of tumor angiogenesis.
Q44589894Synthesis, biodistribution and micro-PET imaging of a potential cancer biomarker carbon-11 labeled MMP inhibitor (2R)-2-[[4-(6-fluorohex-1-ynyl)phenyl]sulfonylamino]-3-methylbutyric acid [11C]methyl ester
Q38974209Targeting the Tumour: Cell Penetrating Peptides for Molecular Imaging and Radiotherapy.
Q99708869The Unique Pharmacometrics of Small Molecule Therapeutic Drug Tracer Imaging for Clinical Oncology

Search more.