| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M304754200 |
| P698 | PubMed publication ID | 14583619 |
| P50 | author | Andreas Radbruch | Q18410254 |
| Ria Baumgrass | Q69931017 | ||
| P2093 | author name string | Gunter Fischer | |
| Matthias Weiwad | |||
| Frank Erdmann | |||
| Andreas Thiel | |||
| Yixin Zhang | |||
| P2860 | cites work | Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex | Q24310797 |
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| Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin | Q24536083 | ||
| Antigen-specific cytometry | Q24804980 | ||
| X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex | Q27729433 | ||
| X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution | Q27731506 | ||
| A functional chaperone triad on the yeast ribosome | Q27930569 | ||
| Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains | Q27933866 | ||
| All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae | Q27937279 | ||
| Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity | Q28140993 | ||
| Transcription factors of the NFAT family: regulation and function | Q28237645 | ||
| Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes | Q28277749 | ||
| Defective T cell development and function in calcineurin A beta -deficient mice | Q28592115 | ||
| Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity | Q28616012 | ||
| Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins | Q29618460 | ||
| The mechanism of action of cyclosporin A and FK506 | Q30014847 | ||
| Reversible inhibition of calcineurin by the polyphenolic aldehyde gossypol. | Q30320912 | ||
| Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. | Q30778570 | ||
| Calcineurin. Structure, function, and inhibition | Q33547330 | ||
| Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin | Q33911404 | ||
| Nucleocytoplasmic shuttling and the control of NF-AT signaling | Q33925566 | ||
| Molecular mechanisms of the protein serine/threonine phosphatases | Q34412727 | ||
| Good fungi gone bad: the corruption of calcineurin | Q34906798 | ||
| Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A? | Q36229942 | ||
| T cell responses in calcineurin A alpha-deficient mice | Q36366258 | ||
| The 3D structure of a cyclosporin analogue in water is nearly identical to the cyclophilin-bound cyclosporin conformation | Q36745076 | ||
| Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B | Q37599093 | ||
| Evidence that calcineurin is rate-limiting for primary human lymphocyte activation | Q39792111 | ||
| Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression | Q42267729 | ||
| Sanglifehrin A, a novel cyclophilin-binding compound showing immunosuppressive activity with a new mechanism of action | Q43628930 | ||
| Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo | Q43687301 | ||
| Chemical genetics resulting from a passion for synthetic organic chemistry | Q50267304 | ||
| Analysis of the kinetics of reversible enzyme inhibition by a general algebraic method. Application to multisite inhibition of the phosphoglycerate kinase from Trypanosoma brucei. | Q52416937 | ||
| Comparative mutational analysis of peptidyl prolyl cis/trans isomerases: active sites of Escherichia coli trigger factor and human FKBP12. | Q54567420 | ||
| Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center. | Q54567511 | ||
| High gradient magnetic cell separation with MACS | Q57339991 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cyclosporine | Q367700 |
| immunosuppression | Q1455316 | ||
| P304 | page(s) | 2470-2479 | |
| P577 | publication date | 2003-10-28 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Substitution in position 3 of cyclosporin A abolishes the cyclophilin-mediated gain-of-function mechanism but not immunosuppression | |
| P478 | volume | 279 |
| Q28238993 | A reassessment of the inhibitory capacity of human FKBP38 on calcineurin |
| Q46652185 | A surface plasmon resonance-based assay for small molecule inhibitors of human cyclophilin A. |
| Q33521776 | Analysis of newly established EST databases reveals similarities between heart regeneration in newt and fish |
| Q35001481 | Augmented photoswitching modulates immune signaling |
| Q44967699 | Branches on the alpha-C atom of cyclosporin A residue 3 result in direct calcineurin inhibition and rapid cyclophilin 18 binding. |
| Q28551403 | Conformational Heterogeneity of Cyclosporin A in Cyclophilin 18 Binding |
| Q45048791 | Cyclosporin A produces distal renal tubular acidosis by blocking peptidyl prolyl cis-trans isomerase activity of cyclophilin |
| Q52894682 | Dephosphorylation of Bcl-10 by calcineurin is essential for canonical NF-κB activation in Th cells. |
| Q33300337 | Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression. |
| Q44901353 | Evaluation of calcineurin/NFAT inhibitor selectivity in primary human Th cells using bar-coding and phospho-flow cytometry |
| Q30317938 | Fine tuning the inhibition profile of cyclosporine A by derivatization of the MeBmt residue |
| Q48445926 | Inhibition of calcineurin by infusion of CsA causes hyperphosphorylation of tau and is accompanied by abnormal behavior in mice |
| Q52924284 | Inhibition of calcineurin-NFAT signaling by the pyrazolopyrimidine compound NCI3. |
| Q28579857 | Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation |
| Q37622487 | Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506? |
| Q28488000 | Role of Ess1 in growth, morphogenetic switching, and RNA polymerase II transcription in Candida albicans |
| Q27490844 | SCY-635, a Novel Nonimmunosuppressive Analog of Cyclosporine That Exhibits Potent Inhibition of Hepatitis C Virus RNA Replication In Vitro |
| Q30318847 | The novel calcineurin inhibitor CN585 has potent immunosuppressive properties in stimulated human T cells. |
| Q40486256 | Unexpected side chain effects at residue 8 of cyclosporin a derivatives allow photoswitching of immunosuppression. |
| Q43003617 | Whole blood flow cytometric measurement of NFATc1 and IL-2 expression to analyze cyclosporine A-mediated effects in T cells |
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