α-lipoic acid protects dopaminergic neurons against MPP+-induced apoptosis by attenuating reactive oxygen species formation

scientific article published on April 24, 2013

α-lipoic acid protects dopaminergic neurons against MPP+-induced apoptosis by attenuating reactive oxygen species formation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/IJMM.2013.1361
P953full work available online athttps://spandidos-publications.com/10.3892/ijmm.2013.1361/download
https://www.spandidos-publications.com/ijmm/32/1/108/download
P698PubMed publication ID23615851
P5875ResearchGate publication ID236328322

P2093author name stringYan Lu
Ming Chang
Ming Yao
Wei Cheng
Da-Wei Li
Zhi-Qiang Liu
Guang-Ren Li
Lin-Sen Hu
P2860cites workMemory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acidQ24530352
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Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidationQ70412768
Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell lineQ71178112
alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in ratsQ71341165
Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant alpha-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study)Q71482533
Chromatographic analysis of lipoic acid and related compoundsQ77613819
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Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance.Q35707591
Lipoic acid as a potential therapy for chronic diseases associated with oxidative stressQ35768380
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PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagyQ36476931
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Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouseQ38677190
The therapeutic use of lipoic acid in diabetes: a current perspective.Q39415158
MPTP toxicity: implications for research in Parkinson's diseaseQ39602394
Protective effect of erythropoietin against 1-methyl-4-phenylpyridinium-induced neurodegenaration in PC12 cellsQ41333380
Alpha-lipoic acid increases intracellular glutathione in a human T-lymphocyte Jurkat cell lineQ41370793
Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's diseaseQ42282056
Effect of DL-alpha-lipoic acid on the status of lipid peroxidation and antioxidant enzymes in various brain regions of aged ratsQ44100002
Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male ratsQ44124925
Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidantsQ44230044
Dose-related cytoprotective effect of alpha-lipoic acid on hydrogen peroxide-induced oxidative stress to pancreatic beta cellsQ46055595
Changes in mitochondrial membrane potential and mitochondrial mass occur independent of the activation of caspase-8 and caspase-3 during CD95-mediated apoptosis in peripheral blood T cellsQ46923947
Lipoic and dihydrolipoic acids as antioxidants. A critical evaluationQ48186626
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
reactive oxygen speciesQ424361
P304page(s)108-114
P577publication date2013-04-24
P1433published inInternational Journal of Molecular MedicineQ6051492
P1476titleα-lipoic acid protects dopaminergic neurons against MPP+-induced apoptosis by attenuating reactive oxygen species formation
P478volume32

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cites work (P2860)
Q89880339A Curcumin Derivative Activates TFEB and Protects Against Parkinsonian Neurotoxicity in Vitro
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Q46252229α-Lipoic acid, functional fatty acid, as a novel therapeutic alternative for central nervous system diseases: A review

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