Metabolism of calcium antagonist Ro 40-5967: a case history of the use of diode-array u.v. spectroscopy and thermospray-mass spectrometry in the elucidation of a complex metabolic pathway

scientific article published on July 1, 1992

Metabolism of calcium antagonist Ro 40-5967: a case history of the use of diode-array u.v. spectroscopy and thermospray-mass spectrometry in the elucidation of a complex metabolic pathway is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3109/00498259209053144
P698PubMed publication ID1455903

P2093author name stringE. Worth
H. R. Wiltshire
K. J. Prior
S. R. Harris
U. M. Kozlowski
P2860cites workTocainide conjugation in humans: novel biotransformation pathway for a primary amineQ42271484
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmetabolic pathwayQ68685
P304page(s)837-857
P577publication date1992-07-01
P1433published inXenobioticaQ1360678
P1476titleMetabolism of calcium antagonist Ro 40-5967: a case history of the use of diode-array u.v. spectroscopy and thermospray-mass spectrometry in the elucidation of a complex metabolic pathway
P478volume22

Reverse relations

cites work (P2860)
Q71377756Effects of mibefradil on intracellular Ca2+ release in cultured rat cardiac fibroblasts and human platelets
Q71795356High-performance liquid chromatographic analysis of mibefradil in dog plasma and urine
Q43831406Interference of a carbamoyl glucuronide metabolite in quantitative liquid chromatography/tandem mass spectrometry
Q73485500Metabolism of the calcium antagonist, mibefradil (POSICORTM, Ro 40-5967). Part III. Comparative pharmacokinetics of mibefradil and its major metabolites in rat, marmoset, cynomolgus monkey and man
Q93899050Metabolism of the calcium antagonist, mibefradil (POSICOR™, Ro 40-5967). Part II. Metabolism in hepatic microsomes from rat, marmoset, cynomolgus monkey, rabbit and man
Q34082998The mibefradil derivative NNC55-0396, a specific T-type calcium channel antagonist, exhibits less CYP3A4 inhibition than mibefradil
Q43743505Use of on-line hydrogen/deuterium exchange to facilitate metabolite identification