Effects of mibefradil on intracellular Ca2+ release in cultured rat cardiac fibroblasts and human platelets

scientific article published on 01 December 1995

Effects of mibefradil on intracellular Ca2+ release in cultured rat cardiac fibroblasts and human platelets is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00168921
P698PubMed publication ID8750922

P2093author name stringK Miyagawa
P Erne
K Hermsmeyer
M Eberhard
P2860cites workA new generation of Ca2+ indicators with greatly improved fluorescence propertiesQ27860793
A set of programs for analysis of kinetic and equilibrium data.Q34072934
Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts. Coupling to signaling systems and gene expressionQ34150245
Activation of the calcium release channel (ryanodine receptor) by heparin and other polyanions is calcium dependent.Q34436186
Calcium-channel drugs: structure-function relationships and selectivity of actionQ36717230
Position of calcium antagonists in antihypertensive therapyQ38152079
Pharmacokinetics of calcium antagonistsQ38199616
Inositol 1,4,5-trisphosphate releases Ca2+ from a Ca2+-transporting membrane vesicle fraction derived from human platelets.Q41359997
The structurally novel Ca2+ channel blocker Ro 40-5967, which binds to the [3H] desmethoxyverapamil receptor, is devoid of the negative inotropic effects of verapamil in normal and failing rat heartsQ41776362
Inositol 1,4,5-trisphosphate-induced calcium release in permeabilized platelets is coupled to hydrolysis of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphateQ42288428
Inhibition of signal Ca2+ in dog coronary arterial vascular muscle cells by Ro 40-5967.Q42497003
Metabolism of calcium antagonist Ro 40-5967: a case history of the use of diode-array u.v. spectroscopy and thermospray-mass spectrometry in the elucidation of a complex metabolic pathwayQ44797118
Potential-dependent inhibition of cardiac Ca2+ inward currents by Ro 40-5967 and verapamil: relation to negative inotropyQ46438854
Resting state block and use independence of rat vascular muscle Ca++ channels by Ro 40-5967.Q54031122
Reactive disulfides trigger Ca2+ release from sarcoplasmic reticulum via an oxidation reaction.Q54102593
Ro 40–5967, in Contrast to Diltiazem, Does Not Reduce Left Ventricular Contractility in Rats with Chronic Myocardial InfarctionQ67689248
Lack of Negative Inotropic Effects of the New Calcium Antagonist Ro 40–5967 in Patients with Stable Angina PectorisQ67709727
Analysis of calcium binding to alpha-lactalbumin using a fluorescent calcium indicatorQ67812880
Increased negative inotropic effect of calcium-channel blockers in hypertrophied and failing rabbit heartQ67898791
Hemodynamic and humoral effects of the novel calcium antagonist Ro 40-5967 in patients with hypertensionQ68045953
Antihypertensive properties of the novel calcium antagonist (1S,2S)-2-[2-[[3-(2-benzimidazolyl)propyl]methylamino] ethyl]-6- fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride in rat models of hypertension. Comparison wiQ68823721
In vitro pharmacologic profile of Ro 40-5967, a novel Ca2+ channel blocker with potent vasodilator but weak inotropic actionQ69080302
Effects of Ro 40-5967, a novel calcium antagonist, on myocardial function during ischemia induced by lowering coronary perfusion pressure in dogs: comparison with verapamilQ69121839
Effects of sulfhydryl reagents and other inhibitors on Ca2+ transport and inositol trisphosphate-induced Ca2+ release from human platelet membranesQ70305983
Selective inhibition of T-type Ca2+ channels by Ro 40-5967Q72018988
Cardiovascular Profile of Ro 40–5967, a New Nondihydropyridine Calcium Antagonist, Delineated in Isolated, Blood-Perfused Dog HeartsQ72098789
Ca2+ channel actions of the non-dihydropyridine Ca2+ channel antagonist Ro 40-5967 in vascular muscle cells cultured from dog coronary and saphenous arteriesQ72104434
Measurement of receptor induced changes in intracellular free calcium in human plateletsQ72411558
Calcium and magnesium binding to rat parvalbuminQ72498641
The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channelsQ72897184
P433issue1
P304page(s)94-101
P577publication date1995-12-01
P1433published inNaunyn-Schmiedeberg's Archives of PharmacologyQ1468251
P1476titleEffects of mibefradil on intracellular Ca2+ release in cultured rat cardiac fibroblasts and human platelets
P478volume353

Reverse relations

cites work (P2860)
Q40569159Induction of apoptosis by the calcium antagonist mibefradil correlates with depolarization of the membrane potential and decreased integrin expression in human lens epithelial cells
Q41557934Prevention of lens epithelial cell growth in vitro using mibefradil-containing PLGA micro particles
Q35645713T-type calcium channel antagonists, mibefradil and NNC-55-0396 inhibit cell proliferation and induce cell apoptosis in leukemia cell lines
Q43762907Torsades de pointes caused by Mibefradil

Search more.