Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis

scientific article published on 6 December 2011

Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/14756366.2011.641015
P698PubMed publication ID22145736

P50authorClaudiu T SupuranQ28211545
P2093author name stringAlfonso Maresca
Fabrizio Carta
Daniela Vullo
P2860cites workStructure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformansQ27653101
Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct--an inhibitor mimicking the sulfonamide and urea binding to the enzymeQ27658617
Carbonic anhydrase inhibitorsQ28219057
Carbonic anhydrases: novel therapeutic applications for inhibitors and activatorsQ28263238
Structure and function of carbonic anhydrases from Mycobacterium tuberculosisQ28486815
Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosisQ28486849
Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamateQ28487300
Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial beta-carbonic anhydrases Rv1284 and Rv3273Q28487474
Structural mechanics of the pH-dependent activity of beta-carbonic anhydrase from Mycobacterium tuberculosisQ28909148
Potent inhibitory effects of benzyl and p-xylidine-bis dithiocarbamate sodium salts on activities of mushroom tyrosinaseQ33491745
Brucella carbonic anhydrases: new targets for designing anti-infective agentsQ33684921
Characterization and inhibition studies of an α-carbonic anhydrase from the endangered sturgeon species Acipenser gueldenstaedti.Q33838825
Carbonic anhydrases: current state of the art, therapeutic applications and future prospectsQ34361209
The alpha and beta classes carbonic anhydrases from Helicobacter pylori as novel drug targetsQ37108508
A roadmap for drug discovery and its translation to small molecule agents in clinical development for tuberculosis treatmentQ37257884
Emerging drugs for active tuberculosisQ37276893
Doomsday postponed? Preventing and reversing epidemics of drug-resistant tuberculosisQ37349855
Recent advances in antituberculous drug development and novel drug targetsQ37754884
Carbonic anhydrase inhibition with natural products: novel chemotypes and inhibition mechanismsQ37783942
The β-carbonic anhydrases from Mycobacterium tuberculosis as drug targets.Q37785567
Carbonic anhydrase inhibitors and activators for novel therapeutic applicationsQ37909406
Interfering with pH regulation in tumours as a therapeutic strategyQ37933052
Bacterial carbonic anhydrases as drug targets: toward novel antibiotics?Q41949186
Carbonic anhydrase inhibitorsQ43042271
Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamateQ43170759
Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.Q43257307
Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar TyphimuriumQ45163943
Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anionsQ46095908
Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamidesQ58863214
P433issue2
P921main subjectMycobacterium tuberculosisQ130971
P304page(s)407-411
P577publication date2011-12-06
P1433published inJournal of Enzyme Inhibition and Medicinal ChemistryQ15708877
P1476titleDithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis
P478volume28

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