Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases.

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Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/14756366.2017.1344236
P932PMC publication ID6445164
P698PubMed publication ID28718328

P50authorClaudiu T SupuranQ28211545
Tiziano TuccinardiQ46649928
Mikhail KrasavinQ55128355
P2093author name stringStanislav Kalinin
Mikhail Korsakov
Muhammet Tanç
Oksana Ronzhina
P2860cites workCrystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-A resolutionQ24683205
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Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzymeQ27730724
Carbonic anhydrases: novel therapeutic applications for inhibitors and activatorsQ28263238
The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and CQ28646334
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibilityQ29547658
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Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit α- and β-Carbonic Anhydrase: X-ray Crystallography and Solution Investigations on 15 IsoformsQ58308152
Analysis of Human Carbonic Anhydrase II: Docking Reliability and Receptor-Based 3D-QSAR StudyQ58308232
Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoformsQ85565913
Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffoldsQ89364741
Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?Q38011235
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Multicomponent chemistry in the synthesis of carbonic anhydrase inhibitorsQ38991576
Structural comparison of sulfodiimine and sulfonamide inhibitors in their complexes with zinc enzymesQ43885240
Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosisQ44803551
Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II.Q45356865
Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds.Q45754839
Carbonic anhydrase inhibitors: in vitro inhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids.Q46014247
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxibQ46806150
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P304page(s)920-934
P577publication date2017-12-01
P1433published inJournal of Enzyme Inhibition and Medicinal ChemistryQ15708877
P1476titlePrimary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases
P478volume32

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cites work (P2860)
Q93008802Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives
Q64263067Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies
Q92610527Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitors
Q93010942Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors

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