Regulation of hypoxia inducible factor-1 by nitric oxide in contrast to hypoxia in microvascular endothelium

scientific article

Regulation of hypoxia inducible factor-1 by nitric oxide in contrast to hypoxia in microvascular endothelium is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-5793(03)00798-1
P698PubMed publication ID12914933
P5875ResearchGate publication ID10616569

P50authorRamesh NatarajanQ42626955
P2093author name stringBernard J Fisher
Alpha A Fowler
P2860cites workThe lipid phosphatase activity of PTEN is critical for its tumor supressor functionQ22007981
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysisQ22009936
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingQ24291102
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylationQ24555773
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylationQ27860876
Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cellsQ28578972
Mitochondrial reactive oxygen species trigger hypoxia-induced transcriptionQ29614203
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensingQ29617570
Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changesQ29617594
PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunitQ30308560
Accumulation of HIF-1alpha under the influence of nitric oxide.Q31835101
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathwayQ33599964
The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.Q33783562
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancerQ35578323
HIF-1 alpha protein as a target for S-nitrosationQ40673725
Atypical mechanism of NF-kappaB activation during reoxygenation stress in microvascular endothelium: a role for tyrosine kinasesQ40700012
Reoxygenating microvascular endothelium exhibits temporal dissociation of NF-kappaB and AP-1 activationQ40732403
Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcriptionQ40749055
Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.Q40754086
Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathwayQ40843321
ERK activation upon hypoxia: involvement in HIF-1 activationQ40898952
Oxygen sensing and molecular adaptation to hypoxiaQ41075727
Complex role of protein phosphorylation in gene activation by hypoxiaQ41131080
Effect of protein kinase and phosphatase inhibitors on expression of hypoxia-inducible factor 1.Q41271374
Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1.Q41324943
Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation.Q41487763
Role of protein kinase Cdelta in transmitting hypoxia signal to HSF and HIF-1.Q43652298
Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxideQ43714163
Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.Q45881488
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.Q52173333
EPAS1 trans-activation during hypoxia requires p42/p44 MAPKQ73176153
Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tensionQ73341950
Staining and quantification of proteins transferred to polyvinylidene fluoride membranesQ73520778
Detection of intracellular nitric oxide using a combination of aldehyde fixatives with 4,5-diaminofluorescein diacetateQ73961762
Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathwayQ74485172
Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activityQ77520388
P433issue1-3
P407language of work or nameEnglishQ1860
P921main subjecthypoxiaQ105688
endotheliumQ111140
P304page(s)99-104
P577publication date2003-08-01
P1433published inFEBS LettersQ1388051
P1476titleRegulation of hypoxia inducible factor-1 by nitric oxide in contrast to hypoxia in microvascular endothelium
P478volume549

Reverse relations

cites work (P2860)
Q90660718Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy
Q37007253Cloning and polymorphisms of yak lactate dehydrogenase B gene
Q28482073Nitric oxide-driven hypoxia initiates synovial angiogenesis, hyperplasia and inflammatory lesions in mice
Q92106562Redox Regulation of the Microcirculation
Q43104701Vitamin C inhibits NO-induced stabilization of HIF-1alpha in HUVECs

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