Mechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain

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Mechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M405537200
P698PubMed publication ID15166225
P5875ResearchGate publication ID8540695

P2093author name stringAlireza R Rezaie
Chandrashekhara Manithody
Philip J Fay
Hironao Wakabayashi
Jan Freas
Keiji Nogami
P2860cites workCleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activityQ28630745
Structure of human factor VIIIQ28630991
Activation of factor VIII and mechanisms of cofactor actionQ34284793
Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIIIQ34556892
Zymogenic and enzymatic properties of the 70-80 loop mutants of factor X/XaQ36526481
Electrostatic interactions in the association of proteins: an analysis of the thrombin-hirudin complexQ41765295
Cofactor activities of factor VIIIa and A2 subunit following cleavage of A1 subunit at Arg336.Q43859307
Identification of a factor Xa-interactive site within residues 337-372 of the factor VIII heavy chainQ44756930
Expression of active human factor VIII from recombinant DNA clonesQ45862746
The size of human factor VIII heterodimers and the effects produced by thrombinQ47207667
Calcium enhances heparin catalysis of the antithrombin-factor Xa reaction by a template mechanism. Evidence that calcium alleviates Gla domain antagonism of heparin binding to factor Xa.Q47921712
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectcoagulation factor x humanQ28859740
P304page(s)33104-33113
P577publication date2004-05-27
P1433published inJournal of Biological ChemistryQ867727
P1476titleMechanisms of interactions of factor X and factor Xa with the acidic region in the factor VIII A1 domain
P478volume279

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cites work (P2860)
Q36412125Characterization of factor VIII inhibitors
Q37734885Does plasmin have anticoagulant activity?
Q45881688Exosite-interactive regions in the A1 and A2 domains of factor VIII facilitate thrombin-catalyzed cleavage of heavy chain
Q36412120Factor VIII structure and function
Q36508875Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites
Q34162849Interaction between mouse adenovirus type 1 and cell surface heparan sulfate proteoglycans
Q36281976Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite
Q42533684Role of P1 residues Arg336 and Arg562 in the activated-Protein-C-catalysed inactivation of Factor VIIIa.
Q35939880Sequences flanking Arg336 in factor VIIIa modulate factor Xa-catalyzed cleavage rates at this site and cofactor function
Q47220570Stable complex formation between serine protease inhibitor and zymogen: coagulation factor X cleaves the Arg393-Ser394 bond in a reactive centre loop of antithrombin in the presence of heparin
Q45869260Study on the efficacy and safety of Xueyou Mixture in treating hemophilia
Q36128237Targeting exosites on blood coagulation proteases
Q46220531The factor VIIIa C2 domain (residues 2228-2240) interacts with the factor IXa Gla domain in the factor Xase complex

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