The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice

scientific article

The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00213-005-0295-X
P698PubMed publication ID16416156
P5875ResearchGate publication ID7356548

P50authorJean-Pierre ChangeuxQ910163
Billy R MartinQ60467790
P2093author name stringM Imad Damaj
Sharon Brown
Carrie L Walters
P2860cites workIn vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in miceQ45083493
Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptorsQ46586967
Characterization of nicotinic receptor-mediated [3H]dopamine release from synaptosomes prepared from mouse striatumQ48434978
Binding of the nicotinic cholinergic antagonist, dihydro-beta-erythroidine, to rat brain tissueQ48594761
A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTXQ48856964
Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal nicotinic receptor alpha subunitsQ48974722
Long-term potentiation of excitatory inputs to brain reward areas by nicotine.Q51381056
Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area.Q51627333
Blockade of nicotine self-administration with nicotinic antagonists in rats.Q52177843
Pharmacologic characterization of nicotine-induced conditioned place preference.Q52268923
A sensitive technique for the detection of the alpha 7 neuronal nicotinic acetylcholine receptor antagonist, methyllycaconitine, in rat plasma and brain.Q52547543
Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine.Q27863674
Pharmacological characterization of nicotine-induced seizures in miceQ28376560
Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptorsQ28505103
Nicotine receptor inactivation decreases sensitivity to cocaineQ28513615
Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nucleiQ28564628
Rat nicotinic acetylcholine receptor alpha2beta2 channels: comparison of functional properties with alpha4beta2 channels in Xenopus oocytesQ28570726
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotineQ28589593
Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currentsQ28592111
Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brainQ28594028
Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brainQ28594253
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving ratsQ29619737
Conditioned place preference: what does it add to our preclinical understanding of drug reward?Q34188090
Achieving tobacco cessation: current status, current problems, future possibilities.Q34858773
The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat.Q43788914
Lesions of the tegmental pedunculopontine nucleus block the rewarding effects and reveal the aversive effects of nicotine in the ventral tegmental area.Q44156202
Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental areaQ44295864
Characterization of spontaneous and precipitated nicotine withdrawal in the mouseQ44582589
P433issue3-4
P304page(s)339-344
P577publication date2006-01-14
P1433published inPsychopharmacologyQ1422802
P1476titleThe beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice
P478volume184

Reverse relations

cites work (P2860)
Q38851564A threshold model for opposing actions of acetylcholine on reward behavior: Molecular mechanisms and implications for treatment of substance abuse disorders.
Q34172963A transcriptional regulatory element critical for CHRNB4 promoter activity in vivo
Q44977420Acute behavioral effects of nicotine in male and female HINT1 knockout mice
Q35203630Acute nicotine administration increases BOLD fMRI signal in brain regions involved in reward signaling and compulsive drug intake in rats
Q38624524Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain
Q35837691Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia
Q48911423Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.
Q35631485Anxiolytic-like and anxiogenic-like effects of nicotine are regulated via diverse action at β2*nicotinic acetylcholine receptors
Q28534828Behavioral and molecular analysis of nicotine-conditioned place preference in zebrafish
Q41891396Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo
Q30491573Beta2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning
Q37164812Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies
Q36349942Bupropion and its main metabolite reverse nicotine chronic tolerance in the mouse
Q37247103Cellular events in nicotine addiction
Q34058860Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity
Q30570256Cocaine-associated odor cue re-exposure increases blood oxygenation level dependent signal in memory and reward regions of the maternal rat brain
Q34360535Conditioned place preference and self-administration induced by nicotine in adolescent and adult rats
Q35181132Contributions of β2 subunit-containing nAChRs to chronic nicotine-induced alterations in cognitive flexibility in mice
Q24650892Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration
Q37535489Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions
Q35647302Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice.
Q38204497Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation
Q30490291Dopamine enables in vivo synaptic plasticity associated with the addictive drug nicotine
Q30597187Dual role of nicotine in addiction and cognition: a review of neuroimaging studies in humans
Q52597124Effect of nicotine and alpha-7 nicotinic modulators on visceral pain-induced conditioned place aversion in mice.
Q33835737Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse
Q37351302Effects of blockade of α4β2 and α7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats
Q42365798Effects of nicotine in combination with drugs described as positive allosteric nicotinic acetylcholine receptor modulators in vitro: discriminative stimulus and hypothermic effects in mice.
Q37291940Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal and nicotine-induced reinstatement of preference in mice
Q36298187Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice
Q26853457Genetic matters: thirty years of progress using mouse models in nicotinic research
Q30485478Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research
Q37573968Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice
Q36453486Genetics of nicotine dependence and pharmacotherapy
Q30491854Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
Q28265155Genetics of smoking and depression
Q30480193Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits
Q37520732Hypocretin mechanisms in nicotine addiction: evidence and speculation
Q64915913Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding.
Q37146387Inhibition of anandamide hydrolysis by cyclohexyl carbamic acid 3'-carbamoyl-3-yl ester (URB597) reverses abuse-related behavioral and neurochemical effects of nicotine in rats
Q30448803Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations
Q35694111Involvement of neuronal β2 subunit-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal: implications for pharmacotherapies
Q45054305In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence
Q37166530Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning.
Q36105359Long-term nicotine exposure depresses dopamine release in nonhuman primate nucleus accumbens
Q28484969Low dose nicotine and antagonism of β2 subunit containing nicotinic acetylcholine receptors have similar effects on affective behavior in mice
Q56529261Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors
Q30497524Mechanisms involved in systemic nicotine-induced glutamatergic synaptic plasticity on dopamine neurons in the ventral tegmental area
Q46364764Medication-related pharmacological manipulations of nicotine self-administration in the rat maintained on fixed- and progressive-ratio schedules of reinforcement
Q30489625Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine
Q26851972Molecular mechanisms underlying behaviors related to nicotine addiction
Q37327392Molecular mechanisms underlying the motivational effects of nicotine
Q27008063Molecules and circuits involved in nicotine addiction: The many faces of smoking
Q90603824More than Smoke and Patches: The Quest for Pharmacotherapies to Treat Tobacco Use Disorder
Q30432964Mouse models for studying genetic influences on factors determining smoking cessation success in humans
Q34012381Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system
Q36137598Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions
Q39059946Neuropeptide systems and new treatments for nicotine addiction
Q88960570New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice
Q37756527Nicotine addiction and nicotinic receptors: lessons from genetically modified mice
Q36920049Nicotine enhances context learning but not context-shock associative learning
Q35031943Nicotine enhances the locomotor stimulating but not the conditioned rewarding effect of ethanol in DBA/2J mice
Q28728978Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials
Q30485318Nicotine withdrawal disrupts new contextual learning
Q45032449Nicotine-induced enhancement of responding for conditioned reinforcement in rats: role of prior nicotine exposure and α4β2 nicotinic receptors
Q47921424Nicotine-motivated behavior in Caenorhabditis elegans requires the nicotinic acetylcholine receptor subunits acr-5 and acr-15.
Q36851620Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation
Q43099250Nicotinic acetylcholine receptors in the mesolimbic pathway: primary role of ventral tegmental area alpha6beta2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement.
Q34631254Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse
Q35966896Nicotinic receptor contributions to smoking: insights from human studies and animal models
Q30451446Nicotinic receptors in the dorsal and ventral hippocampus differentially modulate contextual fear conditioning
Q37055419Nominal association with CHRNA4 variants and nicotine dependence
Q37259323Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference
Q35054656Null mutation of the β2 nicotinic acetylcholine receptor subunit attenuates nicotine withdrawal-induced anhedonia in mice
Q50148077Optically dissecting brain nicotinic receptor function with photo-controllable designer receptors
Q37395740Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes
Q37230901Positive allosteric modulation of α4β2 nicotinic acetylcholine receptors as a new approach to smoking reduction: evidence from a rat model of nicotine self-administration
Q27021772Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype
Q35229091Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens
Q35184641Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior.
Q34173418Reward, addiction, withdrawal to nicotine
Q37106501Rodent models of nicotine reward: what do they tell us about tobacco abuse in humans?
Q30495752Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice
Q46309086Role of beta2-containing nicotinic acetylcholine receptors in auditory event-related potentials
Q50647796Role of α4- and α6-containing nicotinic receptors in the acquisition and maintenance of nicotine self-administration.
Q35831006Role of α7- and β4-containing nicotinic acetylcholine receptors in the affective and somatic aspects of nicotine withdrawal: studies in knockout mice
Q36906652Role of β4* Nicotinic Acetylcholine Receptors in the Habenulo-Interpeduncular Pathway in Nicotine Reinforcement in Mice.
Q37236502Sex differences in response to nicotine in C57Bl/6:129SvEv mice
Q33552906Stimulation of nicotine reward and central cholinergic activity in Sprague-Dawley rats exposed perinatally to a fat-rich diet
Q30487079Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice.
Q42369876TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors
Q34953245Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence
Q92565525Targeting the α4β2- and α7-Subtypes of Nicotinic Acetylcholine Receptors for Smoking Cessation Medication Development
Q33703839The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice
Q47073739The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors.
Q47848449The effects of nicotine in the neonatal quinpirole rodent model of psychosis: Neural plasticity mechanisms and nicotinic receptor changes
Q37291517The endocannabinoid system: a new molecular target for the treatment of tobacco addiction.
Q37353755The endogenous cannabinoid system modulates nicotine reward and dependence
Q34988448The necessity of α4* nicotinic receptors in nicotine-driven behaviors: dissociation between reinforcing and motor effects of nicotine
Q47550611The nicotinic receptor drug sazetidine-A reduces alcohol consumption in mice without affecting concurrent nicotine consumption
Q37416390The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal
Q48221656The role of the α7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice
Q42600613The role of the α7 subunit of the nicotinic acetylcholine receptor on motor coordination in mice treated with methyllycaconitine and anabasine
Q40392015The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse
Q30442195The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse
Q30479050Trace Eyeblink Conditioning is Impaired in α7 but not in β2 Nicotinic Acetylcholine Receptor Knockout Mice
Q26852485Translational research in nicotine dependence
Q36927768Treatment for tobacco dependence: effect on brain nicotinic acetylcholine receptor density
Q37076206Unraveling the neurobiology of nicotine dependence using genetically engineered mice
Q36746829Varenicline ameliorates ethanol-induced deficits in learning in C57BL/6 mice
Q34553486Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration
Q33551855beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking
Q30362464nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives.

Search more.