Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice

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Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M801922200
P698PubMed publication ID18611859

P50authorVincent Walter BloksQ42847358
P2093author name stringFolkert Kuipers
Rick Havinga
Theo H van Dijk
Dirk-Jan Reijngoud
Maaike H Oosterveer
Aldo Grefhorst
P2860cites workRole of LXRs in control of lipogenesisQ24290548
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathwayQ24316367
LXR, a nuclear receptor that defines a distinct retinoid response pathwayQ24317347
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoterQ24550969
OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptorQ24563731
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbetaQ24598068
Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissueQ24677042
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXRQ28513664
Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient miceQ34617976
ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptorsQ36504484
Role of ChREBP in hepatic steatosis and insulin resistance.Q36918305
Hepatic gluconeogenic fluxes and glycogen turnover during fasting in humans. A stable isotope studyQ37372215
Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob miceQ38325289
The nuclear receptor LXR is a glucose sensorQ40190911
Evidence for an indirect transcriptional regulation of glucose-6-phosphatase gene expression by liver X receptorsQ40356891
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particlesQ40720835
Zonation of parenchymal and nonparenchymal metabolism in liverQ41138372
Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose productionQ44102079
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.Q44203895
Hepatic de novo synthesis of glucose 6-phosphate is not affected in peroxisome proliferator-activated receptor alpha-deficient mice but is preferentially directed toward hepatic glycogen stores after a short term fastQ44701457
Quantification of hepatic carbohydrate metabolism in conscious mice using serial blood and urine spotsQ44713538
Enhanced glucose cycling and suppressed de novo synthesis of glucose-6-phosphate result in a net unchanged hepatic glucose output in ob/ob miceQ45187815
Inhibition of mitochondrial fatty acid oxidation in vivo only slightly suppresses gluconeogenesis but enhances clearance of glucose in mice.Q46732235
Dissection of the insulin-sensitizing effect of liver X receptor ligandsQ46795051
Metabolomics (liver and blood profiling) in a mouse model in response to fasting: a study of hepatic steatosisQ46975368
Mass isotopomer analysis: Theoretical and practical considerationsQ52445368
P433issue37
P407language of work or nameEnglishQ1860
P304page(s)25437-25445
P577publication date2008-07-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleLxralpha deficiency hampers the hepatic adaptive response to fasting in mice
P478volume283

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cites work (P2860)
Q34067485CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models
Q45558516Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1
Q38136424Fasting of mice: a review
Q33636261Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice
Q33553422Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice
Q43282312Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice
Q39395189G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux.
Q38160330Hepatic glucose sensing and integrative pathways in the liver
Q36466124Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation.
Q37200875Interrelationship between liver X receptor alpha, sterol regulatory element-binding protein-1c, peroxisome proliferator-activated receptor gamma, and small heterodimer partner in the transcriptional regulation of glucokinase gene expression in liver
Q37273150KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.
Q36129076LRH-1-dependent glucose sensing determines intermediary metabolism in liver
Q38905346Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity
Q37646873Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression
Q37569266Sterol regulation of metabolism, homeostasis, and development