| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M408700200 |
| P698 | PubMed publication ID | 15485886 |
| P2093 | author name string | Roy Zent | |
| Mark Ginsberg | |||
| Christopher Haslett | |||
| Kenneth J Simpson | |||
| Neil C Henderson | |||
| Tariq Sethi | |||
| Alison C Mackinnon | |||
| Elizabeth A Collis | |||
| P2860 | cites work | Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family | Q24314750 |
| Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family | Q24316388 | ||
| Beta1 integrins show specific association with CD98 protein in low density membranes | Q24793681 | ||
| Pro-adhesive and chemotactic activities of thrombospondin-1 for breast carcinoma cells are mediated by alpha3beta1 integrin and regulated by insulin-like growth factor-1 and CD98 | Q28140972 | ||
| Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98) | Q28570781 | ||
| Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies | Q29614313 | ||
| Diversity of gene expression in adenocarcinoma of the lung | Q29616070 | ||
| CD98 induces LFA-1-mediated cell adhesion in lymphoid cells via activation of Rap1. | Q31877684 | ||
| The cytoplasmic tyrosines of integrin subunit beta1 are involved in focal adhesion kinase activation | Q33964961 | ||
| FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth | Q34360984 | ||
| Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase | Q34429291 | ||
| Focal adhesion kinase as a potential target in oncology | Q35058125 | ||
| Integrins, oncogenes, and anchorage independence. | Q36276579 | ||
| Modulation of beta1A integrin functions by tyrosine residues in the beta1 cytoplasmic domain | Q36289167 | ||
| Cross-linking CD98 promotes integrin-like signaling and anchorage-independent growth. | Q39618303 | ||
| Structure, expression and regulation of the murine 4F2 heavy chain. | Q40447822 | ||
| Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity | Q40772047 | ||
| CD98-mediated links between amino acid transport and beta 1 integrin distribution in polarized columnar epithelia. | Q40785867 | ||
| Distinct domains of CD98hc regulate integrins and amino acid transport | Q40835406 | ||
| Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains | Q40900502 | ||
| Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase | Q41060477 | ||
| Phosphoinositide kinases | Q41099687 | ||
| 24 Evaluation of chemical carcinogenicity by in vitro neoplastic transformation | Q41459947 | ||
| Isolation and characterization of a heterodimeric surface antigen on human melanoma cells and evidence that it is the 4F2 cell activation/proliferation molecule | Q41747573 | ||
| Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway | Q42618265 | ||
| Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts | Q42771254 | ||
| Malignant transformation of NIH3T3 cells by overexpression of early lymphocyte activation antigen CD98. | Q42811326 | ||
| Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice. | Q43796891 | ||
| Complementation of dominant suppression implicates CD98 in integrin activation. | Q45939363 | ||
| Identification of a new epitope of the 4F2/44D7 molecular complex present on sarcolemma and isolated cardiac fibers | Q46659024 | ||
| 4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer. | Q47993051 | ||
| Analysis of the expression of the 4F2 surface antigen in normal and neoplastic fibroblastic human cells of embryonic and adult origin | Q49324036 | ||
| Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond. | Q50741101 | ||
| Transformation of BALB3T3 cells caused by over-expression of rat CD98 heavy chain (HC) requires its association with light chain: mis-sense mutation in a cysteine residue of CD98HC eliminates its transforming activity. | Q53407871 | ||
| P433 | issue | 52 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 54731-54741 | |
| P577 | publication date | 2004-10-12 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation | |
| P478 | volume | 279 |
| Q33267755 | Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array. |
| Q53483909 | CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway. |
| Q35912427 | CD98 at the crossroads of adaptive immunity and cancer |
| Q34876558 | CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice |
| Q34328557 | CD98 increases renal epithelial cell proliferation by activating MAPKs |
| Q38727999 | CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia |
| Q37427983 | CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior. |
| Q46066210 | CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling. |
| Q41976946 | CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. |
| Q33722588 | CD98hc (SLC3A2) mediates integrin signaling. |
| Q36547682 | CD98hc (SLC3A2) regulation of skin homeostasis wanes with age |
| Q37166768 | CD98hc facilitates B cell proliferation and adaptive humoral immunity |
| Q42502374 | Characterization of the human intestinal CD98 promoter and its regulation by interferon-gamma |
| Q89848840 | Development of a high affinity Anticalin® directed against human CD98hc for theranostic applications |
| Q37111705 | Discovery of SLC3A2 cell membrane protein as a potential gastric cancer biomarker: implications in molecular imaging |
| Q37465582 | Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression |
| Q90152813 | Galectin-3 Is a Potential Mediator for Atherosclerosis |
| Q51722974 | Galectin-3 regulates hepatic progenitor cell expansion during liver injury. |
| Q35482842 | Homeostatic and innate immune responses: role of the transmembrane glycoprotein CD98. |
| Q37397313 | Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2. |
| Q28066805 | Integrins in the Spotlight of Cancer |
| Q36646618 | Intestinal epithelial CD98 directly modulates the innate host response to enteric bacterial pathogens. |
| Q36042167 | Intestinal epithelial CD98 synthesis specifically modulates expression of colonic microRNAs during colitis. |
| Q37014916 | Intestinal epithelial CD98: an oligomeric and multifunctional protein |
| Q37506015 | Inverse immunological responses induced by allergic rhinitis and head and neck squamous cell carcinoma |
| Q34336163 | Loss of the integrin-activating transmembrane protein Fam38A (Piezo1) promotes a switch to a reduced integrin-dependent mode of cell migration |
| Q50647926 | Mutation of the 4F2 heavy-chain carboxy terminus causes y+ LAT2 light-chain dysfunction. |
| Q42795817 | NIH3T3 cells overexpressing CD98 heavy chain resist early G1 arrest and apoptosis induced by serum starvation |
| Q24675057 | Nonvesicular release of glutamate by glial xCT transporters suppresses glutamate receptor clustering in vivo |
| Q58577796 | Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis |
| Q39682618 | Proximity biotinylation provides insight into the molecular composition of focal adhesions at the nanometer scale |
| Q33292271 | RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program |
| Q38864270 | Rapid phenotypic fingerprinting of cell products by robust measurement of ubiquitous surface markers |
| Q33809330 | ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes |
| Q52652369 | Regulation of RAW264.7 macrophage polarization on smooth and rough surface topographies by galectin-3. |
| Q47101416 | SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer |
| Q38333251 | Targeted therapy of acute myeloid leukemia |
| Q36350091 | The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1. |
| Q33643277 | The membrane-spanning domain of CD98 heavy chain promotes alpha(v)beta3 integrin signals in human extravillous trophoblasts |
| Q55000052 | The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells. |
| Q27647581 | The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane |
| Q55354182 | Therapeutic Antibodies for Myeloid Neoplasms-Current Developments and Future Directions. |
| Q36462476 | Ubiquitylation of CD98 limits cell proliferation and clonal expansion |
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