Galectin-3 Is a Potential Mediator for Atherosclerosis

scientific article published on 14 February 2020

Galectin-3 Is a Potential Mediator for Atherosclerosis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1155/2020/5284728
P932PMC publication ID7042544
P698PubMed publication ID32149158

P50authorLiming YangQ89259685
P2093author name stringRui Wang
Hong Li
Yinghong Zheng
Ziyu Gao
Zhongni Liu
P2860cites workInhibition of Galectin-3 Alleviates Cigarette Smoke Extract-Induced Autophagy and Dysfunction in Endothelial Progenitor CellsQ91317712
Negative Risk Markers for Cardiovascular Events in the ElderlyQ91615599
Galectin-3 Levels and Outcomes After Myocardial Infarction: A Population-Based StudyQ91895158
[Myocardial Strain Properties in Patients with Chronic Heart Failure]Q92517796
Galectin-3 aggravates ox-LDL-induced endothelial dysfunction through LOX-1 mediated signaling pathwayQ92962373
Prognostic biomarkers in acute coronary syndromeQ26738521
Galectin-3: its role in asthma and potential as an anti-inflammatory targetQ27023534
Matrilysin-1 (MMP7) cleaves galectin-3 and inhibits wound healing in intestinal epithelial cellsQ28118886
Intracellular functions of galectinsQ28201120
Galectins. Structure and function of a large family of animal lectinsQ28246794
Intensive versus moderate lipid lowering with statins after acute coronary syndromesQ29619716
Recent insights into the cellular biology of atherosclerosisQ30300194
Prognostic value of galectin-3, a novel marker of fibrosis, in patients with chronic heart failure: data from the DEAL-HF studyQ33529398
Galectin-3 in Peripheral Artery Disease. Relationships with Markers of Oxidative Stress and Inflammation.Q33754984
Secretion of the galectin family of mammalian carbohydrate-binding proteinsQ33783731
Modified citrus pectin inhibits galectin-3 function to reduce atherosclerotic lesions in apoE-deficient miceQ33828006
Aldosterone induced galectin-3 secretion in vitro and in vivo: from cells to humansQ34122713
Galectinomics: finding themes in complexityQ34148905
Galectin-3 predicts response to statin therapy in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA).Q34269132
Genetic and pharmacological inhibition of galectin-3 prevents cardiac remodeling by interfering with myocardial fibrogenesisQ34316944
Galectins as modulators of tumour progressionQ34381235
Galectin-3: an open-ended storyQ34494555
Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fractionQ34528187
Galectin-3: a novel mediator of heart failure development and progressionQ34995162
Galectin-3, a biomarker linking oxidative stress and inflammation with the clinical outcomes of patients with atherothrombosisQ35026202
Critical role of galectin-3 in phagocytosis by macrophagesQ35169042
Utility of galectin-3 as a prognostic biomarker in heart failure: where do we stand?Q35286926
Cardiac dysfunction and noncardiac dysfunction as precursors of heart failure with reduced and preserved ejection fraction in the communityQ35671472
Progression of left ventricular diastolic dysfunction and risk of heart failureQ35719757
Galectin-3 expression in human atherosclerotic lesions.Q35765442
Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages.Q35798551
Role of endothelial dysfunction in atherosclerosisQ35806066
Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.Q35809897
Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetesQ35842591
Galectin-3-induced oxidized low-density lipoprotein promotes the phenotypic transformation of vascular smooth muscle cellsQ36089958
Galectin-3 gene inactivation reduces atherosclerotic lesions and adventitial inflammation in ApoE-deficient miceQ36357458
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.Q36811564
Spatial and temporal expression, and statin responsiveness of galectin-1 and galectin-3 in murine atherosclerosisQ36844332
Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitorsQ37096426
Large artery intracranial occlusive disease: a large worldwide burden but a relatively neglected frontier.Q37183959
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammationQ37443866
Association of galectin-3 with markers of myocardial function, atherosclerosis and vascular fibrosis in patients with rheumatoid arthritisQ57796538
Berberine alleviates oxidized low-density lipoprotein-induced macrophage activation by downregulating galectin-3 via the NF-κB and AMPK signaling pathwaysQ58608459
Galectin-3 Is an Amplifier of Inflammation in Atherosclerotic Plaque Progression Through Macrophage Activation And Monocyte ChemoattractionQ62657999
NT-proBNP is a weak indicator of cardiac function and haemodynamic response to exercise in chronic heart failureQ64282928
The role of galectin-3 in endocytosis of advanced glycation end products and modified low density lipoproteinsQ73405607
Galectin-3 and the development of heart failure after acute coronary syndrome: pilot experience from PROVE IT-TIMI 22Q82644905
Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertensionQ84539872
Mineralocorticoid receptor antagonists modulate galectin-3 and interleukin-33/ST2 signaling in left ventricular systolic dysfunction after acute myocardial infarctionQ86135613
Association between serum galectin-3 levels and coronary atherosclerosis and plaque burden/structure in patients with type 2 diabetes mellitusQ87139750
[Impact of plasma pro-B-type natriuretic peptide amino-terminal and galectin-3 levels on the predictive capacity of the LIPID Clinical Risk Scale in stable coronary disease]Q87587551
Galectin-3 exacerbates ox-LDL-mediated endothelial injury by inducing inflammation via integrin β1-RhoA-JNK signaling activationQ90399605
Doxazosin Stimulates Galectin-3 Expression and Collagen Synthesis in HL-1 Cardiomyocytes Independent of Protein Kinase C PathwayQ37516514
Galectin-3-null mice display defective neutrophil clearance during acute inflammationQ37629666
Comprehensive review of the prognostic value of galectin-3 in heart failureQ38177147
The ARCHITECT galectin-3 assay: comparison with other automated and manual assays for the measurement of circulating galectin-3 levels in heart failureQ38194209
Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transitionQ38293221
Atherosclerosis - A matter of unresolved inflammationQ38417380
The potential role of natriuretic peptides and other biomarkers in heart failure diagnosis, prognosis and managementQ38551693
Comparative study of galectin-3 and B-type natriuretic peptide as biomarkers for the diagnosis of heart failureQ38687046
Galectin‑3 induces the phenotype transformation of human vascular smooth muscle cells via the canonical Wnt signalingQ38845124
Downregulating galectin-3 inhibits proinflammatory cytokine production by human monocyte-derived dendritic cells via RNA interferenceQ38909319
Vitexin alleviates ox-LDL-mediated endothelial injury by inducing autophagy via AMPK signaling activationQ38910927
Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient miceQ39191329
Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-PheQ39518249
Extracellular galectin-3 counteracts adhesion and exhibits chemoattraction in Helicobacter pylori-infected gastric cancer cellsQ39695000
Regulation of alternative macrophage activation by galectin-3.Q40016366
Role of galectin-3 as an adhesion molecule for neutrophil extravasation during streptococcal pneumoniaQ40753134
Differences in galectin-3, a biomarker of fibrosis, between participants with peripheral artery disease and participants with normal ankle-brachial indexQ40765198
Predictive value of Galectin-3 for the occurrence of coronary artery disease and prognosis after myocardial infarction and its association with carotid IMT values in these patients: A mid-term prospective cohort studyQ40939847
Galectin-3 deficiency accelerates high-fat diet-induced obesity and amplifies inflammation in adipose tissue and pancreatic isletsQ40944709
Galectin-3 gene (LGALS3) expression in experimental atherosclerosis and cultured smooth muscle cells.Q41020090
Overexpression of microRNA-138 alleviates human coronary artery endothelial cell injury and inflammatory response by inhibiting the PI3K/Akt/eNOS pathwayQ41241181
Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathwaysQ42077799
NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient miceQ42284239
Galectin-3 plasma levels and coronary artery disease: a new possible biomarker of acute coronary syndrome.Q43493519
Galectin-3 expression in macrophages is signaled by Ras/MAP kinase pathway and up-regulated by modified lipoproteinsQ44466555
Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cellsQ44688770
CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformationQ45107882
The association between galectin-3 and occurrence of reinfarction early after first myocardial infarction treated invasivelyQ45129579
Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophilsQ46320323
A Role for galectin-3 in renal tissue damage triggered by ischemia and reperfusion injuryQ46461255
Galectin-3 enhances avian H5N1 influenza A virus-induced pulmonary inflammation by promoting NLRP3 inflammasome activation.Q47549239
Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity.Q47649685
Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An UpdateQ47653100
The galectin-3/RAGE dyad modulates vascular osteogenesis in atherosclerosisQ47703344
Galectin-3 is associated with coronary plaque burden and obstructive sleep apnea syndrome severityQ47768450
Low NT-proBNP levels in overweight and obese patients do not rule out a diagnosis of heart failure with preserved ejection fraction.Q47854367
Accelerated lipid-induced atherogenesis in galectin-3-deficient mice: role of lipoxidation via receptor-mediated mechanisms.Q48024001
Galectins: a family of animal beta-galactoside-binding lectinsQ48084852
The fibrosis marker galectin-3 and outcome in the general populationQ48821773
Quinapril treatment abolishes diabetes-associated atherosclerosis in RAGE/apolipoprotein E double knockout mice.Q50804043
Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection.Q51011747
Diagnostic significance of serum galectin-3 levels in heart failure with preserved ejection fraction.Q52139416
Value and level of galectin-3 in acute myocardial infarction patients undergoing primary percutaneous coronary intervention.Q53141520
Inhibition of Galectin-3 Pathway Prevents Isoproterenol-Induced Left Ventricular Dysfunction and Fibrosis in Mice.Q53205052
Is galectin-3 a biomarker, a player-or both-in the presence of coronary atherosclerosis?Q53233664
Galectin-3 predicts long-term cardiovascular death in high-risk patients with coronary artery disease.Q53630691
Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors.Q55379330
Inflammation in atherosclerosisQ57295305
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P304page(s)5284728
P577publication date2020-02-14
P1433published inJournal of Immunology ResearchQ26841936
P1476titleGalectin-3 Is a Potential Mediator for Atherosclerosis
P478volume2020

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Q99240850Evaluation of Galectin-3 as a Novel Diagnostic Biomarker in Patients with Heart Failure with Preserved Ejection Fractioncites workP2860

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