Telomerase activity-independent function of telomerase reverse transcriptase is involved in acrylamide-induced neuron damage

scientific article published on 27 November 2013

Telomerase activity-independent function of telomerase reverse transcriptase is involved in acrylamide-induced neuron damage is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/10520295.2013.855323
P698PubMed publication ID24279610

P2093author name stringP Zhang
X Liu
J Wang
X Hu
H Pan
P2860cites workHuman telomerase acts as a hTR-independent reverse transcriptase in mitochondriaQ24338425
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosisQ28250587
Analysis of acrylamide, a carcinogen formed in heated foodstuffsQ34143312
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosisQ34551106
Ways of dying: multiple pathways to apoptosis.Q35560936
Telomerase activity, cell proliferation, and cancerQ36166271
Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondriaQ36285737
Mitochondrial reactive oxygen species and Ca2+ signalingQ36499631
A review of the toxicology of acrylamideQ36816929
Minireview on the toxicity of dietary acrylamideQ36955612
Regulation of DNA fragmentation: the role of caspases and phosphorylationQ37823657
Telomerase reverse transcriptase: a novel neuroprotective mechanism involved in neonatal hypoxic-ischemic brain injuryQ37914365
Acrylamide induces cell death in neural progenitor cells and impairs hippocampal neurogenesis.Q39758894
hTERT extends proliferative lifespan and prevents oxidative stress-induced apoptosis in human lens epithelial cellsQ40404554
hTERT antagonizes p53-induced apoptosis independently of telomerase activity.Q40479122
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.Q40487014
Conversion of Bcl-2 to a Bax-like death effector by caspasesQ41073693
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damageQ42450430
hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer CellsQ42479814
Evidence of acrylamide induced oxidative stress and neurotoxicity in Drosophila melanogaster - its amelioration with spice active enrichment: relevance to neuropathyQ42716750
Effects of the carbamates fenoxycarb, propamocarb and propoxur on energy supply, glucose utilization and SH-groups in neuronsQ44777868
Protective role of Panax ginseng extract standardized with ginsenoside Rg3 against acrylamide-induced neurotoxicity in rats.Q46549039
Effects of acrylamide on the nervous tissue antioxidant system and sciatic nerve electrophysiology in the rat.Q46602460
mRNA expression of antioxidant enzymes (SOD, CAT and GSH-Px) and lipid peroxidative stress in liver of Atlantic salmon (Salmo salar) exposed to hyperoxic water during smoltificationQ46656229
Acrylamide-induced oxidative stress and biochemical perturbations in ratsQ46847358
The neuroprotective role of TERT via an antiapoptotic mechanism in neonatal rats after hypoxia-ischemia brain injuryQ48598878
Mitochondria protection of baicalein against oxidative damage via induction of manganese superoxide dismutaseQ50436558
Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?Q55068261
P433issue5
P304page(s)327-335
P577publication date2013-11-27
P1433published inBiotechnic & HistochemistryQ4915326
P1476titleTelomerase activity-independent function of telomerase reverse transcriptase is involved in acrylamide-induced neuron damage
P478volume89

Reverse relations

cites work (P2860)
Q38701653Acrylamide-derived cytotoxic, anti-proliferative, and apoptotic effects on A549 cells.
Q28388277Causes of genome instability: the effect of low dose chemical exposures in modern society
Q47157011Scientific Opinion on acrylamide in food
Q60112361The non-canonical functions of telomerase: to turn off or not to turn off

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