Tat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptides

scientific article published in February 2005

Tat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2004.08.037
P698PubMed publication ID15661389

P50authorBernard RoquesQ2898544
Bernard A. LafontQ37649405
Bruno HurtrelQ115605015
Valérie MonceauxQ115605017
P2093author name stringClaude Desgranges
Roger Le Grand
Sylviane Muller
Guillaume Belliard
Anne-Marie Aubertin
Emmanuel Moreau
P2860cites workQuantifying the uncertainty in forecasts of anthropogenic climate changeQ28141336
Tat as a transcriptional activator and a potential therapeutic target for HIV-1.Q34033142
From the outside in: extracellular activities of HIV Tat.Q34033148
The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individualsQ34104267
The LTR72 mutant of heat-labile enterotoxin of Escherichia coli enhances the ability of peptide antigens to elicit CD4(+) T cells and secrete gamma interferon after coapplication onto bare skinQ34123358
Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replicationQ34336210
Tat-neutralizing antibodies in vaccinated macaquesQ34755910
HIV-1 Tat-based vaccines: from basic science to clinical trialsQ34978901
Tat as one key to HIV-induced immune pathogenesis and Tat (correction of Pat) toxoid as an important component of a vaccineQ35993736
Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS.Q36011366
Generation and characterization of neutralizing human monoclonal antibodies against human immunodeficiency virus type 1 Tat antigenQ37010956
Outcome of simian-human immunodeficiency virus strain 89.6p challenge following vaccination of rhesus macaques with human immunodeficiency virus Tat proteinQ39683362
Prevention of disease induced by a partially heterologous AIDS virus in rhesus monkeys by using an adjuvanted multicomponent protein vaccineQ39699309
Highly stable oligomerization forms of HIV-1 Tat detected by monoclonal antibodies and requirement of monomeric forms for the transactivating function on the HIV-1 LTR.Q40887674
HIV-1 Tat protein as a potential AIDS vaccineQ41091310
The human uniqueness of HIV: innate immunity and the viral Tat proteinQ43421877
B-cell epitopes in HIV-1 Tat and Rev proteins colocalize with T-cell epitopes and with functional domainsQ43499852
Targeting Tat and IFN(alpha) as a therapeutic AIDS vaccineQ44092065
Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P).Q45012988
Important B-cell epitopes for neutralization of human immunodeficiency virus type 1 Tat in serum samples of humans and different animal species immunized with Tat protein or peptidesQ45572850
Mucosal delivery of the human immunodeficiency virus-1 Tat protein in mice elicits systemic neutralizing antibodies, cytotoxic T lymphocytes and mucosal IgA.Q45722188
SHIV89.6P pathogenicity in cynomolgus monkeys and control of viral replication and disease onset by human immunodeficiency virus type 1 Tat vaccine.Q45739668
Minimization of chronic plasma viremia in rhesus macaques immunized with synthetic HIV-1 Tat peptides and infected with a chimeric simian/human immunodeficiency virus (SHIV33).Q45742451
Antibodies against full-length Tat protein and some low-molecular-weight Tat-peptides correlate with low or undetectable viral load in HIV-1 seropositive patientsQ47216468
Evaluation in Rhesus Macaques of Tat and Rev-Targeted Immunization as a Preventive Vaccine against Mucosal Challenge with SHIV-BX08Q57081491
Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccineQ59511395
High viral load and CD4 lymphopenia in rhesus and cynomolgus macaques infected by a chimeric primate lentivirus constructed using the env, rev, tat, and vpu genes from HIV-1 LaiQ71530285
Antibodies to Tat and Vpr in the GRIV cohort: differential association with maintenance of long-term non-progression status in HIV-1 infectionQ73138904
Specificity and effect on apoptosis of Tat antibodies from vaccinated and SHIV-infected rhesus macaques and HIV-infected individualsQ73520478
Immunogenicity of HIV-1 IIIB and SHIV 89.6P Tat and Tat toxoids in rhesus macaques: induction of humoral and cellular immune responsesQ78417376
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1399-1407
P577publication date2005-02-01
P1433published inVaccineQ7907941
P1476titleTat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptides
P478volume23

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cites work (P2860)
Q35785031A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhe
Q27333734Biocompatible anionic polymeric microspheres as priming delivery system for effetive HIV/AIDS Tat-based vaccines
Q30381447HIV-1 Tat-based vaccines: an overview and perspectives in the field of HIV/AIDS vaccine development.
Q39933791Immunoprevalence of the CD4+ T-cell response to HIV Tat and Vpr proteins is provided by clustered and disperse epitopes, respectively
Q42930401Induction of anti-Tat neutralizing antibodies by the CyaA vector targeting dendritic cells: influence of the insertion site and of the delivery of multicopies of the dominant Tat B-cell epitope
Q34756847The grafting of universal T-helper epitopes enhances immunogenicity of HIV-1 Tat concurrently improving its safety profile

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