A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhe

scientific article published on 17 January 2007

A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhe is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.02453-06
P932PMC publication ID1866031
P698PubMed publication ID17229693

P50authorBarbara EnsoliQ21255143
Marjorie Robert-GuroffQ30651738
Norman L. LetvinQ98917684
Birgit Korioth-SchmitzQ57016730
P2093author name stringV S Kalyanaraman
David C Montefiori
Aurelio Cafaro
Thorsten Demberg
Richard Grant
David Venzon
Dilani Dombagoda
L Jean Patterson
Ranajit Pal
Eun Mi Lee
Irene Kalisz
Kay Larsen
Adam Buzby
Megan J Heath
Ruth H Florese
P2860cites workOf mice and not men: differences between mouse and human immunologyQ28246229
The multiple functions of HIV-1 Tat: proliferation versus apoptosisQ28271014
Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expressionQ28301068
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodiesQ29619015
Boosting of SIV-specific immune responses in rhesus macaques by repeated administration of Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinantsQ30976921
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope proteinQ31135334
Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strainsQ33785321
Detection of antibody-dependent complement-mediated inactivation of both autologous and heterologous virus in primary human immunodeficiency virus type 1 infectionQ33834852
Replicating rather than nonreplicating adenovirus-human immunodeficiency virus recombinant vaccines are better at eliciting potent cellular immunity and priming high-titer antibodiesQ33911986
Vectored Gag and Env but not Tat show efficacy against simian-human immunodeficiency virus 89.6P challenge in Mamu-A*01-negative rhesus monkeysQ33984182
Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responsesQ34105993
Identification of a potential HIV-induced source of bystander-mediated apoptosis in T cells: upregulation of trail in primary human macrophages by HIV-1 tat.Q34269140
Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251Q64378954
Specificity and effect on apoptosis of Tat antibodies from vaccinated and SHIV-infected rhesus macaques and HIV-infected individualsQ73520478
Antibodies to the HIV-1 Tat protein correlated with nonprogression to AIDS: a rationale for the use of Tat toxoid as an HIV-1 vaccineQ77296129
Comparative analysis of HIV-1 Tat variantsQ81171039
Dominance of CD8 responses specific for epitopes bound by a single major histocompatibility complex class I molecule during the acute phase of viral infectionQ34358162
Reservoir cells no longer detectable after a heterologous SHIV challenge with the synthetic HIV-1 Tat Oyi vaccine.Q34488930
Rhesus macaque polyclonal and monoclonal antibodies inhibit simian immunodeficiency virus in the presence of human or autologous rhesus effector cellsQ35024276
Vaccination with tat toxoid attenuates disease in simian/HIV-challenged macaquesQ35114827
Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeysQ35123128
Potent, persistent induction and modulation of cellular immune responses in rhesus macaques primed with Ad5hr-simian immunodeficiency virus (SIV) env/rev, gag, and/or nef vaccines and boosted with SIV gp120.Q35182076
Efficient inhibition of HIV-1 replication in human immature monocyte-derived dendritic cells by purified anti-HIV-1 IgG without induction of maturationQ35849709
An adenovirus-simian immunodeficiency virus env vaccine elicits humoral, cellular, and mucosal immune responses in rhesus macaques and decreases viral burden following vaginal challengeQ35898573
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HIV vaccines: new frontiers in vaccine developmentQ36534852
Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivationQ36639380
Protection against mucosal simian immunodeficiency virus SIV(mac251) challenge by using replicating adenovirus-SIV multigene vaccine priming and subunit boostingQ36954239
Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responsesQ37285535
Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteinsQ37742938
Outcome of simian-human immunodeficiency virus strain 89.6p challenge following vaccination of rhesus macaques with human immunodeficiency virus Tat proteinQ39683362
The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection.Q39805021
Nonneutralizing antibodies are able to inhibit human immunodeficiency virus type 1 replication in macrophages and immature dendritic cellsQ40274328
HIV-1 tat protein modulates the generation of cytotoxic T cell epitopes by modifying proteasome composition and enzymatic activityQ40517749
Tat-mediated protein delivery can facilitate MHC class I presentation of antigensQ41160245
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.Q41335848
Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat proteinQ41349382
Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1.Q41925734
The presence of anti-Tat antibodies is predictive of long-term nonprogression to AIDS or severe immunodeficiency: findings in a cohort of HIV-1 seroconvertersQ43671904
Multiprotein HIV type 1 clade B DNA/MVA vaccine: construction, safety, and immunogenicity in MacaquesQ43953620
Improved vaccine protection from simian AIDS by the addition of nonstructural simian immunodeficiency virus genesQ44666320
Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P).Q45012988
Tat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptidesQ45231619
Sequence conservation and antibody cross-recognition of clade B human immunodeficiency virus (HIV) type 1 Tat protein in HIV-1-infected Italians, Ugandans, and South AfricansQ45710857
Quantitative evaluation of simian immunodeficiency virus infection using NASBA technologyQ45743923
Human immunodeficiency virus type 1 Rev- and Tat-specific cytotoxic T lymphocyte frequencies inversely correlate with rapid progression to AIDS.Q45761033
The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexesQ45869894
HIV-1 Tat raises an adjuvant-free humoral immune response controlled by its core region and its ability to form cysteine-mediated oligomersQ46830857
Antibodies against full-length Tat protein and some low-molecular-weight Tat-peptides correlate with low or undetectable viral load in HIV-1 seropositive patientsQ47216468
Long-term protection against SHIV89.6P replication in HIV-1 Tat vaccinated cynomolgus monkeys.Q51998598
Maintenance of serological memory by polyclonal activation of human memory B cells.Q52008907
An adenovirus-based HIV subtype B prime/boost vaccine regimen elicits antibodies mediating broad antibody-dependent cellular cytotoxicity against non-subtype B HIV strains.Q52840793
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemiaQ57075698
Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccineQ59511395
Candidate HIV-1 Tat vaccine development: from basic science to clinical trialsQ59647820
Enhanced cellular immunity to SIV Gag following co-administration of adenoviruses encoding wild-type or mutant HIV Tat and SIV GagQ61641083
Dual role of HIV Tat in regulation of apoptosis in T cellsQ63351479
Full-length HIV-1 Tat protein necessary for a vaccineQ63384219
Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responsesQ64377680
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
P304page(s)3414-3427
P577publication date2007-01-17
P1433published inJournal of VirologyQ1251128
P1476titleA replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques
P478volume81

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cites work (P2860)
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