Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector.

scientific article

Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector. is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1158505T
P356DOI10.1371/JOURNAL.PONE.0158505
P932PMC publication ID4938603
P698PubMed publication ID27391605

P50authorDavid J VenzonQ56925544
Michael A ThomasQ110416123
Marjorie Robert-GuroffQ30651738
Iskra TueroQ30651764
P2093author name stringTinashe Nyanhete
P2860cites workE4orf1 limits the oncolytic potential of the E1B-55K deletion mutant adenovirusQ37110666
The adenoviral E1B 55-kilodalton protein controls expression of immune response genes but not p53-dependent transcriptionQ37145192
Systemic neutralizing antibodies induced by long interval mucosally primed systemically boosted immunization correlate with protection from mucosal SHIV challengeQ37297052
Effect of NKG2D ligand expression on host immune responsesQ37764003
Hepatitis C virus-specific cellular and humoral immune responses following immunization with a multi-epitope fusion proteinQ39466259
Expression and characterization of a single-chain polypeptide analogue of the human immunodeficiency virus type 1 gp120-CD4 receptor complexQ39593524
Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B.Q43112464
Long-term protection of chimpanzees against high-dose HIV-1 challenge induced by immunizationQ44592013
China approves world's first oncolytic virus therapy for cancer treatmentQ45419325
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine developmentQ56993265
Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responsesQ64377680
Pre-clinical evaluation of a replication-competent recombinant adenovirus serotype 4 vaccine expressing influenza H5 hemagglutininQ28731982
Roles for the E4 orf6, orf3, and E1B 55-kilodalton proteins in cell cycle-independent adenovirus replicationQ33649728
Vaccine protection against a heterologous, non-syncytium-inducing, primary human immunodeficiency virus.Q33786386
Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boostingQ34007261
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfectionQ34562704
From ONYX-015 to armed vaccinia viruses: the education and evolution of oncolytic virus developmentQ34577135
CD8+CD44(hi) but not CD4+CD44(hi) memory T cells mediate potent graft antilymphoma activity without GVHDQ34707286
Effects of the deletion of early region 4 (E4) open reading frame 1 (orf1), orf1-2, orf1-3 and orf1-4 on virus-host cell interaction, transgene expression, and immunogenicity of replicating adenovirus HIV vaccine vectorsQ35021632
HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaquesQ35032794
Pre-clinical development of a recombinant, replication-competent adenovirus serotype 4 vector vaccine expressing HIV-1 envelope 1086 clade C.Q35061529
A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rheQ35785031
IgG2a restriction of murine antibodies elicited by viral infectionsQ36352342
Adenovirus serotype 5 E1A sensitizes tumor cells to NKG2D-dependent NK cell lysis and tumor rejectionQ36404019
Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: a randomised, double-blind, placebo-controlled, phase 1 studyQ36621905
Packaging capacity and stability of human adenovirus type 5 vectors.Q36653293
E1A and E1B proteins inhibit inflammation induced by adenovirusQ36854089
Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transportQ36894173
Protection against mucosal simian immunodeficiency virus SIV(mac251) challenge by using replicating adenovirus-SIV multigene vaccine priming and subunit boostingQ36954239
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
oncolytic virusQ1560099
P304page(s)e0158505
P577publication date2016-07-08
P1433published inPLOS OneQ564954
P1476titleBeyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector
P478volume11

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cites work (P2860)
Q96640817Mucosal-associated invariant T (MAIT) cells provide B-cell help in vaccinated and subsequently SIV-infected Rhesus Macaques
Q40059020Novel viral vectors in infectious diseases
Q41699675Oncolytic Viruses-Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer

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