Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines.

scientific article published on March 2009

Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.0803115
P932PMC publication ID2744397
P698PubMed publication ID19265150
P5875ResearchGate publication ID24180986

P50authorBarbara EnsoliQ21255143
Marjorie Robert-GuroffQ30651738
P2093author name stringPeng Xiao
Aurelio Cafaro
Thorsten Demberg
David Venzon
Kay Larsen
L Ebonita Summers
LaRene Kuller
Ruth H Florese
P2860cites workTat protein induces self-perpetuating permissivity for productive HIV-1 infectionQ24683211
Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytesQ24683736
Correlation between immunologic responses to a recombinant glycoprotein 120 vaccine and incidence of HIV-1 infection in a phase 3 HIV-1 preventive vaccine trialQ28305565
Cellular uptake of the tat protein from human immunodeficiency virusQ29620627
Boosting of SIV-specific immune responses in rhesus macaques by repeated administration of Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinantsQ30976921
Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope proteinQ31135334
Serum and effector-cell antibody-dependent cellular cytotoxicity (ADCC) activity remains high during human immunodeficiency virus (HIV) disease progressionQ45844475
Failure of ADCC to predict HIV-associated disease progression or outcome in a haemophiliac cohortQ45883512
Relationship between antibody-dependent cellular cytotoxicity, plasma HIV type 1 RNA, and CD4+ lymphocyte count.Q45987356
Antibody-dependent cellular cytotoxicity is directed against both the gp120 and gp41 envelope proteins of HIV.Q46588920
Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rateQ46775963
Antibodies against full-length Tat protein and some low-molecular-weight Tat-peptides correlate with low or undetectable viral load in HIV-1 seropositive patientsQ47216468
An adenovirus-based HIV subtype B prime/boost vaccine regimen elicits antibodies mediating broad antibody-dependent cellular cytotoxicity against non-subtype B HIV strains.Q52840793
A simplified method for the rapid fluorometric assessment of antibody-dependent cell-mediated cytotoxicity.Q52841139
The therapeutic phase I trial of the recombinant native HIV-1 Tat proteinQ57665211
Candidate HIV-1 Tat vaccine development: from basic science to clinical trialsQ59647820
The Tat protein broadens T cell responses directed to the HIV-1 antigens Gag and Env: Implications for the design of new vaccination strategies against AIDSQ61641064
Enhanced cellular immunity to SIV Gag following co-administration of adenoviruses encoding wild-type or mutant HIV Tat and SIV GagQ61641083
Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responsesQ64377680
Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251Q64378954
Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodiesQ67674705
IgG subclass response to HIV in relation to antibody-dependent cellular cytotoxicity at different clinical stagesQ67999489
HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progressionQ71396764
Antibodies to the HIV-1 Tat protein correlated with nonprogression to AIDS: a rationale for the use of Tat toxoid as an HIV-1 vaccineQ77296129
Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDSQ78678676
Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strainsQ33785321
Nef from pathogenic simian immunodeficiency virus is a negative factor for vaccinia virusQ33840818
Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cellsQ33844334
Replicating rather than nonreplicating adenovirus-human immunodeficiency virus recombinant vaccines are better at eliciting potent cellular immunity and priming high-titer antibodiesQ33911986
The HIV-1 regulatory proteins Tat and Rev are frequently targeted by cytotoxic T lymphocytes derived from HIV-1-infected individualsQ34104267
The trans-activator gene of HTLV-III is essential for virus replicationQ34161962
HIV-1 Tat vaccinesQ34556390
HIV-1 Tat-based vaccines: from basic science to clinical trialsQ34978901
Do not underestimate the power of antibodies--lessons from adoptive transfer of antibodies against HIV.Q35023530
Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeysQ35123128
Potent, persistent induction and modulation of cellular immune responses in rhesus macaques primed with Ad5hr-simian immunodeficiency virus (SIV) env/rev, gag, and/or nef vaccines and boosted with SIV gp120.Q35182076
A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rheQ35785031
A call for replicating vector prime-protein boost strategies in HIV vaccine designQ35851801
An adenovirus-simian immunodeficiency virus env vaccine elicits humoral, cellular, and mucosal immune responses in rhesus macaques and decreases viral burden following vaginal challengeQ35898573
Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS.Q36011366
Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivationQ36639380
Protection against mucosal simian immunodeficiency virus SIV(mac251) challenge by using replicating adenovirus-SIV multigene vaccine priming and subunit boostingQ36954239
Passive immunization as tool to identify protective HIV-1 Env epitopesQ37017827
Natural killer cells from human immunodeficiency virus (HIV)-infected individuals are an important source of CC-chemokines and suppress HIV-1 entry and replication in vitroQ37387255
Anti-HIV-1 ADCC.Q38754869
Tat-specific binding IgG and disease progression in HIV type 1-infected UgandansQ38876519
Extracellular HIV-1 tat protein up-regulates the expression of surface CXC-chemokine receptor 4 in resting CD4+ T cells.Q39443021
Evaluation of passively transferred, nonneutralizing antibody-dependent cellular cytotoxicity-mediating IgG in protection of neonatal rhesus macaques against oral SIVmac251 challenge.Q40291422
Antibody-dependent cellular cytotoxicity via humoral immune epitope of Nef protein expressed on cell surfaceQ40592103
Why do we not have an HIV vaccine and how can we make one? .Q40859536
Antibody-dependent cellular cytotoxicity in HIV infections.Q40993761
HIV-1 Tat protein as a potential AIDS vaccineQ41091310
Human immunodeficiency virus type 1 Nef protein on the cell surface is cytocidal for human CD4+ T cellsQ41168546
Effect of antibody to HIV-1 Tat protein on viral replication in vitro and progression of HIV-1 disease in vivo.Q41267357
Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat proteinQ41349382
Evidence for a defect of antibody-dependent cellular cytotoxic (ADCC) effector function and anti-HIV gp120/41-specific ADCC-mediating antibody titres in HIV-infected individualsQ41471715
Block of HIV-1 infection by a combination of antisense tat RNA and TAR decoys: a strategy for control of HIV-1Q41471931
Human immunodeficiency virus type 1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis.Q41522490
Expression of human immunodeficiency virus type 1 Nef antigen on the surface of acutely and persistently infected human T cells.Q41530887
Antibody-dependent cellular cytotoxicity independently predicts survival in severely immunocompromised human immunodeficiency virus-infected patientsQ41689302
Clustered localization of oligomeric Nef protein of human immunodeficiency virus type 1 on the cell surfaceQ42063537
The presence of anti-Tat antibodies is predictive of long-term nonprogression to AIDS or severe immunodeficiency: findings in a cohort of HIV-1 seroconvertersQ43671904
Anti-GP 120 antibodies from HIV seropositive individuals mediate broadly reactive anti-HIV ADCC.Q43725371
Speed of progression to AIDS and degree of antibody response to accessory gene products of HIV-1.Q43984746
Possible beneficial effects of neutralizing antibodies and antibody-dependent, cell-mediated cytotoxicity in human immunodeficiency virus infectionQ44032654
Development of a whole-virus multiplex flow cytometric assay for antibody screening of a specific pathogen-free primate colonyQ45423142
In vitro reduction of virus infectivity by antibody-dependent cell-mediated immunityQ45752500
Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infectionQ45756087
Human immunodeficiency virus type 1 Rev- and Tat-specific cytotoxic T lymphocyte frequencies inversely correlate with rapid progression to AIDS.Q45761033
Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).Q45838520
Natural and antibody-dependent cytotoxicity in different clinical stages of human immunodeficiency virus type 1 infectionQ45843965
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
immunizationQ1415366
vaccineQ134808
P304page(s)3718-3727
P577publication date2009-03-01
P1433published inJournal of ImmunologyQ3521441
P1476titleContribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines
P478volume182

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