The Antibody Response against HIV-1

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The Antibody Response against HIV-1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1101/CSHPERSPECT.A007039
P3181OpenCitations bibliographic resource ID2383962
P932PMC publication ID3253031
P698PubMed publication ID22315717
P5875ResearchGate publication ID221815855

P2093author name stringL. Morris
J. Overbaugh
P2860cites workBreadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progressionQ37356036
Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external regionQ37410792
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogensQ37456354
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?Q37519312
Specificities of broadly neutralizing anti-HIV-1 seraQ37667735
HIV-1 superinfection and its implications for vaccine designQ37807440
Identification and characterization of sera from HIV-infected individuals with broad cross-neutralizing activity against group M (env clade A-H) and group O primary HIV-1 isolatesQ38900264
Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys.Q39457063
Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same siteQ39699375
Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals.Q39879382
Unlocking the secrets of CTL and NK cellsQ40422879
Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllersQ40659603
Features of HIV-1 that could influence maternal-child transmissionQ41449046
Preferential use of the VH5-51 gene segment by the human immune response to code for antibodies against the V3 domain of HIV-1Q41816066
Continuous viral escape and selection by autologous neutralizing antibodies in drug-naive human immunodeficiency virus controllersQ43215260
Diversity in HIV-1 envelope V1-V3 sequences early in infection reflects sequence diversity throughout the HIV-1 genome but does not predict the extent of sequence diversity during chronic infectionQ43466756
Mother-to-child transmission of human immunodeficiency virus type 1: correlation with neutralizing antibodies against primary isolatesQ44219287
Polymorphism of Fc receptor IIa for IgG in infants is associated with susceptibility to perinatal HIV-1 infectionQ44277098
The genetic fate of molecularly cloned simian immunodeficiency virus in experimentally infected macaquesQ44357802
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infectionQ45744790
Virological and immunological features of long-term human immunodeficiency virus-infected individuals who have remained asymptomatic compared with those who have progressed to acquired immunodeficiency syndrome.Q45753210
Correlation between humoral responses to human immunodeficiency virus type 1 envelope and disease progression in early-stage infectionQ45753336
Neutralizing antibody and perinatal transmission of human immunodeficiency virus type 1. New York City Perinatal HIV Transmission Collaborative Study GroupQ45756465
Augmented serum neutralizing activity against primary human immunodeficiency virus type 1 (HIV-1) isolates in two groups of HIV-1-infected long-term nonprogressorsQ45759636
Neutralizing antibody responses to human immunodeficiency virus type 1 in primary infection and long-term-nonprogressive infectionQ45760115
Neutralizing and infection-enhancing antibody responses to human immunodeficiency virus type 1 in long-term nonprogressorsQ45772545
Vertical transmission of human immunodeficiency virus type 1: autologous neutralizing antibody, virus load, and virus phenotypeQ45785271
Selective transmission of human immunodeficiency virus type-1 variants from mothers to infantsQ45867857
Relationship between antibody-dependent cellular cytotoxicity, plasma HIV type 1 RNA, and CD4+ lymphocyte count.Q45987356
FcgammaRIIa genotype predicts progression of HIV infection.Q46017436
Lack of neutralizing antibody response to HIV-1 predisposes to superinfection.Q46078929
Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibodyQ46352552
Fc receptor but not complement binding is important in antibody protection against HIV.Q46545827
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workersQ46690098
Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rateQ46775963
Prevention of HIV infection by passive immunization with HIV immunoglobulinQ47571809
Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmissionQ47878972
Revisiting the role of neutralizing antibodies in mother-to-child transmission of HIV-1.Q51942600
Cross‐Reactive Neutralizing Humoral Immunity Does Not Protect from HIV Type 1 Disease ProgressionQ56886558
Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251Q64378954
HIV-specific cellular and humoral immune responses in primary HIV infectionQ71621033
Neutralizing antibodies and viral characteristics in mother-to-child transmission of HIV-1Q72371328
Course of specific T lymphocyte cytotoxicity, plasma and cellular viral loads, and neutralizing antibody titers in 17 recently seroconverted HIV type 1-infected patientsQ73851292
Neutralizing antibodies are positively associated with CD4+ T-cell counts and T-cell function in long-term AIDS-free infectionQ77386243
A longitudinal study of neutralizing antibodies and disease progression in HIV-1-infected subjectsQ77399464
Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDSQ78678676
HIV vaccine research: the way forwardQ81697043
Oral HIV-exposure elicits mucosal HIV-neutralizing antibodies in uninfected men who have sex with menQ83124960
Genotypic and phenotypic characterization of HIV-1 patients with primary infectionQ22242245
Antibody vs. HIV in a clash of evolutionary titansQ24536059
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infectionQ24538985
Structural definition of a conserved neutralization epitope on HIV-1 gp120Q24655948
Gender differences in HIV-1 diversity at time of infectionQ24706473
Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120Q27643185
Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41Q27666159
Strong cytotoxic T cell and weak neutralizing antibody responses in a subset of persons with stable nonprogressing HIV type 1 infectionQ28286243
Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infectionQ28304764
Correlation between immunologic responses to a recombinant glycoprotein 120 vaccine and incidence of HIV-1 infection in a phase 3 HIV-1 preventive vaccine trialQ28305565
Complement lysis activity in autologous plasma is associated with lower viral loads during the acute phase of HIV-1 infectionQ28766705
Antibody neutralization and escape by HIV-1Q29547345
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine targetQ29547347
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in ThailandQ29547531
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodiesQ29614531
Rapid evolution of the neutralizing antibody response to HIV type 1 infectionQ29618603
Structure of a V3-containing HIV-1 gp120 coreQ29619014
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionQ29619510
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1Q29619511
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1Q29619512
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.Q30367176
Cross-clade neutralization patterns among HIV-1 strains from the six major clades of the pandemic evaluated and compared in two different models.Q30369026
Neutralization activity in a geographically diverse East London cohort of human immunodeficiency virus type 1-infected patients: clade C infection results in a stronger and broader humoral immune response than clade B infectionQ30392301
Human immunodeficiency virus vaccine trialsQ30424366
Molecular analysis of HIV-1 gp120 antibody response using isotype IgM and IgG phage display libraries from a long-term non-progressor HIV-1-infected individualQ30784281
Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathwaysQ33504599
Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infectionQ33504604
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individualsQ33526340
HIV-1 and influenza antibodies: seeing antigens in new waysQ33552488
Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodiesQ33614365
Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies.Q33647300
Temporal analysis of HIV envelope sequence evolution and antibody escape in a subtype A-infected individual with a broad neutralizing antibody responseQ33664910
Functional properties of the HIV-1 subtype C envelope glycoprotein associated with mother-to-child transmissionQ33749206
Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levelsQ33780649
Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cellsQ33844334
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitroQ33853775
Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaquesQ33966586
Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy.Q34009945
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicityQ34057782
HIV‐1 Transmission Biology: Selection and Characteristics of Infecting VirusesQ34158525
B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infectionQ34239109
Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infantQ34301874
Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 populationQ34314341
The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infectionQ34317025
Regional clustering of shared neutralization determinants on primary isolates of clade C human immunodeficiency virus type 1 from South AfricaQ34332009
Specificity of the autologous neutralizing antibody responseQ34415389
Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120.Q34428738
Human immunodeficiency virus type 1 (HIV-1) diversity at time of infection is not restricted to certain risk groups or specific HIV-1 subtypesQ34439417
Effect of humoral immune responses on controlling viremia during primary infection of rhesus monkeys with simian immunodeficiency virusQ34468698
Lymphocyte-mediated cytotoxicity.Q34542250
Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positioQ34583767
B cells in HIV infection and diseaseQ34605780
Neutralizing antibodies do not mediate suppression of human immunodeficiency virus type 1 in elite suppressors or selection of plasma virus variants in patients on highly active antiretroviral therapyQ34647680
Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responsesQ34651668
Role of maternal autologous neutralizing antibody in selective perinatal transmission of human immunodeficiency virus type 1 escape variantsQ34717113
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremiaQ34848486
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individualsQ34962766
The breadth and potency of passively acquired human immunodeficiency virus type 1-specific neutralizing antibodies do not correlate with the risk of infant infectionQ34982698
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infectionQ35076717
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaquesQ35101333
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern AfricaQ35140032
epitopes immediately below the base of the V3 loop of gp120 as targets for the initial autologous neutralizing antibody response in two HIV-1 subtype B-infected individualsQ35192660
Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1.Q35603504
Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infectionQ35635163
Maternal neutralizing antibodies against a CRF01_AE primary isolate are associated with a low rate of intrapartum HIV-1 transmissionQ35744396
Diversity in virus populations from genital secretions and peripheral blood from women recently infected with human immunodeficiency virus type 1.Q35852888
Inter- and intraclade neutralization of human immunodeficiency virus type 1: genetic clades do not correspond to neutralization serotypes but partially correspond to gp120 antigenic serotypes.Q35853750
Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donorsQ35857221
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infectionQ35857268
Clade-specific differences between human immunodeficiency virus type 1 clades B and C: diversity and correlations in C3-V4 regions of gp120.Q35857408
Comparison of heterologous neutralizing antibody responses of human immunodeficiency virus type 1 (HIV-1)- and HIV-2-infected Senegalese patients: distinct patterns of breadth and magnitude distinguish HIV-1 and HIV-2 infectionsQ35857480
Antiviral antibodies are necessary for control of simian immunodeficiency virus replicationQ35857503
The consequence of passive administration of an anti-human immunodeficiency virus type 1 neutralizing monoclonal antibody before challenge of chimpanzees with a primary virus isolateQ35869892
Lessons in nonhuman primate models for AIDS vaccine research: from minefields to milestonesQ36009232
Antibodies: can they protect against HIV infection?Q36173023
In vivo efficacy of human immunodeficiency virus neutralizing antibodies: estimates for protective titersQ36424125
HIV transmissionQ36526615
Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1Q36625449
Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infectionQ36647820
Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeysQ36683893
Alterations in potential sites for glycosylation predominate during evolution of the simian immunodeficiency virus envelope gene in macaquesQ36702206
Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS.Q36829102
Autologous neutralizing humoral immunity and evolution of the viral envelope in the course of subtype B human immunodeficiency virus type 1 infectionQ36845710
Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodiesQ36884458
Importance of the V1/V2 loop region of simian-human immunodeficiency virus envelope glycoprotein gp120 in determining the strain specificity of the neutralizing antibody responseQ36949880
Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.Q36974754
Human immunodeficiency virus type 1 superinfection occurs despite relatively robust neutralizing antibody responsesQ36994644
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodiesQ37033269
Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infectionQ37033294
Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaquesQ37033311
Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individualsQ37033400
GP41-specific antibody blocks cell-free HIV type 1 transcytosis through human rectal mucosa and model colonic epithelium.Q37063527
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithmQ37247974
Cross-subtype neutralization sensitivity despite monoclonal antibody resistance among early subtype A, C, and D envelope variants of human immunodeficiency virus type 1Q37256644
Relationship of human immunodeficiency virus type 1 sequence heterogeneity to stage of diseaseQ37273122
Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donorsQ37333772
Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines.Q37347813
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)a007039
P577publication date2012-01-01
P1433published inCold Spring Harbor Perspectives in MedicineQ21042440
P1476titleThe Antibody Response against HIV-1
P478volume2

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