Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase

scientific article published in December 2004

Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1014242278
P356DOI10.1023/B:MCBI.0000049376.50242.7F
P698PubMed publication ID15663199

P50authorGabriel RabinovichQ17987510
Marta A ToscanoQ130239222
Mercedes FuertesQ37841931
Norberto ZwirnerQ42880727
Juan M. IlarreguiQ44762461
P2093author name stringLeonardo Fainboim
Natalia Rubinstein
Luciana L Molinero
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Galectin-1 exerts immunomodulatory and protective effects on concanavalin A-induced hepatitis in miceQ73401711
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Expression of galectins-1 and -3 correlates with defective mononuclear cell apoptosis in patients with juvenile idiopathic arthritisQ74385158
Activated rat macrophages produce a galectin-1-like protein that induces apoptosis of T cells: biochemical and functional characterizationQ74557548
Activation-induced expression of MICA on T lymphocytes involves engagement of CD3 and CD28Q78058070
Role of mitogen-activated protein kinases in activation-induced apoptosis of T cellsQ78127309
Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1Q78127337
God must love galectins; he made so many of themQ33751857
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Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosisQ36375186
Cell-specific transcriptional regulation and reactivation of galectin-1 gene expression are controlled by DNA methylation of the promoter region.Q36560044
Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.Q37367583
Progress in deciphering the information content of the 'glycome'--a crescendo in the closing years of the millenniumQ38299610
Expression and function of galectin-3, a beta-galactoside-binding protein in activated T lymphocytesQ38301765
Molecular mechanisms implicated in galectin-1-induced apoptosis: activation of the AP-1 transcription factor and downregulation of Bcl-2.Q38309944
Involvement of CD2 and CD3 in galectin-1 induced signaling in human Jurkat T-cellsQ38316354
Beta-galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cellsQ38334060
Regulated expression of a 16-kd galectin-like protein in activated rat macrophages.Q38361325
Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.Q39451191
Regulated expression and effect of galectin-1 on Trypanosoma cruzi-infected macrophages: modulation of microbicidal activity and survivalQ39529473
Transmembrane signaling by the interleukin-2 receptor: progress and conundrumsQ40790156
Galectin-1 induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transductionQ40848658
The family of metazoan metal-independent beta-galactoside-binding lectins: structure, function and molecular evolutionQ40860039
Regulation of CD45-induced signaling by galectin-1 in Burkitt lymphoma B cellsQ40886933
T cell activation signals up-regulate p38 mitogen-activated protein kinase activity and induce TNF-alpha production in a manner distinct from LPS activation of monocytes.Q40978696
Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre- and post-implantation developmentQ42612637
Galectin-1 is overexpressed in nasal polyps under budesonide and inhibits eosinophil migrationQ43890804
Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophagesQ44355242
Galectin-1 suppresses experimental colitis in miceQ44429812
Galectin-3 expression in macrophages is signaled by Ras/MAP kinase pathway and up-regulated by modified lipoproteinsQ44466555
Dimeric galectin-1 induces surface exposure of phosphatidylserine and phagocytic recognition of leukocytes without inducing apoptosisQ44508461
The sugar code in drug deliveryQ44768275
Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.Q46031717
Apoptosis of T cells mediated by galectin-1.Q46356564
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilegeQ47860342
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)177-185
P577publication date2004-12-01
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleRegulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase
P478volume267

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