Galectin-1 exerts immunomodulatory and protective effects on concanavalin A-induced hepatitis in mice

scientific article published on 01 February 2000

Galectin-1 exerts immunomodulatory and protective effects on concanavalin A-induced hepatitis in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.510310220
P698PubMed publication ID10655263

P50authorGiuseppe ServilloQ43159137
P2093author name stringS Fiorucci
A Morelli
L Santucci
B Federici
F Cammilleri
P2860cites workRecombinant human β-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitisQ43820997
Apoptosis of T cells mediated by galectin-1.Q46356564
Galectins: a family of animal beta-galactoside-binding lectinsQ48084852
Apoptosis in cultured rat hepatocytes: The effects of tumour necrosis factor α and interferon γQ67804136
Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin AQ71215744
Prevention and therapy with electrolectin of experimental autoimmune myasthenia gravis in rabbitsQ71763169
Galectin-1 modulates human melanoma cell adhesion to lamininQ72200702
Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in miceQ72349073
Essential roles of the Fas ligand in the development of hepatitisQ73206042
Contribution of Fas ligand to T cell-mediated hepatic injury in miceQ73760660
Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in miceQ74477596
TNFalpha processing enzyme inhibitors prevent aspirin-induced TNFalpha release and protect against gastric mucosal injury in ratsQ77654720
Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1Q78127337
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometryQ29617253
Transcription factor CREM coordinates the timing of hepatocyte proliferation in the regenerating liver.Q30448764
A T cell-dependent experimental liver injury in mice inducible by concanavalin AQ35603939
T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6.Q36363056
Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cellsQ36364533
Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and deathQ36367540
Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosisQ36375186
Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytesQ36377257
Cytotoxic T cells and viral hepatitisQ37365416
Beta-galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cellsQ38334060
Galectins: versatile modulators of cell adhesion, cell proliferation, and cell deathQ38336667
A rapid method for the isolation of functional thymus-derived murine lymphocytesQ39512856
Metastasis of human colon cancer is altered by modifying expression of the beta-galactoside-binding protein galectin 3.Q41022285
Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic miceQ41736950
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)399-406
P577publication date2000-02-01
P1433published inHepatologyQ15724398
P1476titleGalectin-1 exerts immunomodulatory and protective effects on concanavalin A-induced hepatitis in mice
P478volume31

Reverse relations

cites work (P2860)
Q444382118-[3H]-hydroxy-2-(di-n-propylamino)tetralin binding sites in blood lymphocytes of rats and the modulation by mitogens and immobilization
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Q40563755Astilbin prevents concanavalin A-induced liver injury by reducing TNF-alpha production and T lymphocytes adhesion.
Q34192497Development of a Nascent Galectin-1 Chimeric Molecule for Studying the Role of Leukocyte Galectin-1 Ligands and Immune Disease Modulation
Q33263474Differential liver protein expression during schistosomiasis
Q41643007Effect of exogenous galectin-1 on leukocyte migration: modulation of cytokine levels and adhesion molecules.
Q38254055Evolving mechanistic insights into galectin functions
Q58803547Extracellular galectins as controllers of cytokines in hematological cancer
Q42077799Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways
Q42694566Galectin-1 Impairs the Generation of Anti-Parasitic Th1 Cell Responses in the Liver during Experimental Visceral Leishmaniasis
Q43890804Galectin-1 is overexpressed in nasal polyps under budesonide and inhibits eosinophil migration
Q26825120Galectin-1 research in T cell immunity: past, present and future
Q44429812Galectin-1 suppresses experimental colitis in mice
Q34693483Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?
Q37457505Galectins in the Pathogenesis of Rheumatoid Arthritis
Q28283659Galectins: structure, function and therapeutic potential
Q35180105Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression
Q38174863Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma
Q39026528In vitro selection of the 3'-untranslated regions of the human liver mRNA that bind to the HCV nonstructural protein 5B.
Q46879852Induction of galectin-1 by TGF-β1 accelerates fibrosis through enhancing nuclear retention of Smad2.
Q45885229Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation-mediated hepatocarcinogenesis
Q36900466Lack of galectin-1 or galectin-3 alters B cell deletion and anergy in an autoantibody transgene model
Q47946450Lactose Binding Induces Opposing Dynamics Changes in Human Galectins Revealed by NMR-Based Hydrogen-Deuterium Exchange
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