| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/HMG/DDL467 |
| P8608 | Fatcat ID | release_vlq224shmrcrtov3tcd3ok7h34 |
| P698 | PubMed publication ID | 17189290 |
| P5875 | ResearchGate publication ID | 6611796 |
| P2093 | author name string | Jun Z Li | |
| Richard M Myers | |||
| Anne N T Strehlow | |||
| P2860 | cites work | A bacterial artificial chromosome library for sequencing the complete human genome | Q22065763 |
| Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin | Q22254045 | ||
| A huntingtin-associated protein enriched in brain with implications for pathology | Q24303499 | ||
| Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors | Q24303560 | ||
| Huntingtin contains a highly conserved nuclear export signal | Q24303895 | ||
| Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons | Q24317574 | ||
| HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain | Q24318878 | ||
| HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system | Q24320108 | ||
| Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series | Q24537164 | ||
| Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease | Q24554218 | ||
| Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 - new vectors for in vitro and in vivo delivery | Q24802976 | ||
| Emerging roles for TGF-beta1 in nervous system development | Q36152409 | ||
| The role of matrix metalloproteinases in the morphogenesis of the cerebellar cortex | Q36328452 | ||
| Iron dysregulation and neurodegeneration: the molecular connection | Q36432205 | ||
| Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation | Q36823776 | ||
| Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene | Q37432151 | ||
| Huntington's disease. Pathogenesis and management | Q39460676 | ||
| YACs, BACs, PACs and MACs: artificial chromosomes as research tools | Q40534960 | ||
| Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription | Q40764541 | ||
| Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease | Q40782711 | ||
| In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets | Q42488533 | ||
| Huntington's disease gene (IT15) is widely expressed in human and rat tissues | Q42502776 | ||
| Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues | Q42503942 | ||
| Widespread expression of Huntington's disease gene (IT15) protein product | Q42684112 | ||
| Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain | Q44092333 | ||
| Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses | Q44092340 | ||
| Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. | Q45291767 | ||
| Huntingtin localization in brains of normal and Huntington's disease patients | Q45295341 | ||
| Decreased expression of striatal signaling genes in a mouse model of Huntington's disease | Q45300376 | ||
| Genomic structure of the human plasma prekallikrein gene, identification of allelic variants, and analysis in end-stage renal disease. | Q47822282 | ||
| A modular, positive selection bacterial artificial chromosome vector with multiple cloning sites. | Q47955313 | ||
| Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome | Q48611307 | ||
| Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain | Q49020588 | ||
| Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo | Q24813199 | ||
| A comparison of normalization methods for high density oligonucleotide array data based on variance and bias | Q27860710 | ||
| FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis | Q28141525 | ||
| Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes | Q28189644 | ||
| Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease | Q28202050 | ||
| The hunt for huntingtin function: interaction partners tell many different stories | Q28203006 | ||
| PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains | Q28204582 | ||
| HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis | Q28209859 | ||
| Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways | Q28277799 | ||
| Huntingtin interacts with a family of WW domain proteins | Q28279245 | ||
| Normal huntingtin function: an alternative approach to Huntington's disease | Q28281904 | ||
| SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates | Q28288296 | ||
| Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes | Q28302701 | ||
| Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue | Q28506834 | ||
| Inactivation of the mouse Huntington's disease gene homolog Hdh | Q28509662 | ||
| Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form | Q28509836 | ||
| Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice | Q28510424 | ||
| Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development | Q28588430 | ||
| Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles | Q28589989 | ||
| Life without huntingtin: normal differentiation into functional neurons | Q28590704 | ||
| Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion | Q28594526 | ||
| Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice | Q28594828 | ||
| An efficient recombination system for chromosome engineering in Escherichia coli | Q29615038 | ||
| A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA | Q29615197 | ||
| Secreted antagonists of the Wnt signalling pathway | Q29615521 | ||
| Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95. | Q30168237 | ||
| Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells | Q30779186 | ||
| Instability of CAG repeats in Huntington's disease: relation to parental transmission and age of onset | Q33674159 | ||
| Nervous system proteoglycans as modulators of neurite outgrowth | Q33855404 | ||
| Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies | Q33920421 | ||
| Trinucleotide repeat length instability and age of onset in Huntington's disease | Q34357407 | ||
| Characterization and localization of the Huntington disease gene product | Q34662553 | ||
| Transcriptional abnormalities in Huntington disease | Q35113363 | ||
| Huntingtin-protein interactions and the pathogenesis of Huntington's disease | Q35704403 | ||
| Functions of heparan sulfate proteoglycans in cell signaling during development | Q35962679 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 391-409 | |
| P577 | publication date | 2006-12-22 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | Wild-type huntingtin participates in protein trafficking between the Golgi and the extracellular space | |
| P478 | volume | 16 |
| Q34627072 | Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage |
| Q37142133 | Acetylation within the First 17 Residues of Huntingtin Exon 1 Alters Aggregation and Lipid Binding. |
| Q64924739 | Cancer: From Wild-Type to Mutant Huntingtin. |
| Q27649395 | Crystal Structure at 2.8 Å of Huntingtin-Interacting Protein 1 (HIP1) Coiled-Coil Domain Reveals a Charged Surface Suitable for HIP1 Protein Interactor (HIPPI) |
| Q37760791 | Current understanding on the pathogenesis of polyglutamine diseases |
| Q30441792 | Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts |
| Q39626281 | HIV gene expression from intact proviruses positioned in bacterial artificial chromosomes at integration sites previously identified in latently infected T cells |
| Q30353778 | Huntingtin Is Required for Neural But Not Cardiac/Pancreatic Progenitor Differentiation of Mouse Embryonic Stem Cells In vitro. |
| Q33529116 | Huntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP. |
| Q24294765 | Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis |
| Q24312814 | Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport |
| Q98471370 | Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities |
| Q35286098 | Huntington's Disease and Striatal Signaling. |
| Q42472433 | Huntington's disease and mitochondrial alterations: emphasis on experimental models |
| Q34313991 | Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission |
| Q28477022 | Increased prothrombin, apolipoprotein A-IV, and haptoglobin in the cerebrospinal fluid of patients with Huntington's disease |
| Q37356257 | Mitochondrial structural and functional dynamics in Huntington's disease |
| Q37776087 | Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease |
| Q30419653 | Multiple phenotypes in Huntington disease mouse neural stem cells |
| Q37308357 | Mutant huntingtin and mitochondrial dysfunction |
| Q35747131 | Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease |
| Q35645271 | Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease |
| Q21092441 | Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration |
| Q33713689 | Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice. |
| Q39124557 | Proteins Containing Expanded Polyglutamine Tracts and Neurodegenerative Disease |
| Q42382351 | Real-time imaging of Huntingtin aggregates diverting target search and gene transcription |
| Q34999535 | Recent advances in our understanding of neurodegeneration |
| Q37691461 | Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects |
| Q37839534 | Small changes, big impact: posttranslational modifications and function of huntingtin in Huntington disease. |
| Q34994813 | Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis |
| Q38748493 | The Effects of Graded Levels of Calorie Restriction: X. Transcriptomic Responses of Epididymal Adipose Tissue |
| Q64039854 | The effects of huntingtin-lowering: what do we know so far? |
| Q36110838 | The emerging role of the first 17 amino acids of huntingtin in Huntington's disease |
| Q35868172 | Thiol-disulfide Oxidoreductases TRX1 and TMX3 Decrease Neuronal Atrophy in a Lentiviral Mouse Model of Huntington's Disease |
| Q35024695 | Transcription, epigenetics and ameliorative strategies in Huntington's Disease: a genome-wide perspective |
| Q100559962 | Wild-type huntingtin regulates human macrophage function |
| Q24316303 | pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking |
Search more.