Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus–induced disease progression

scientific article published on October 2, 2003

Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus–induced disease progression is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2003-03-0874
P953full work available at URLhttp://www.bloodjournal.org/content/103/3/973.full.pdf
http://ashpublications.org/blood/article-pdf/103/3/973/1695136/zh800304000973.pdf
P698PubMed publication ID14525780
P5875ResearchGate publication ID9065923

P2093author name stringGuido Silvestri
Mirko Paiardini
Marie-Claire Gauduin
Alagarraju Muthukumar
Donald L. Sodora
Harold M. McClure
Aneta Wozniakowski
R. Paul Johnson
P2860cites workIncreased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasisQ28141430
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infectionQ29547852
Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccinesQ33644522
Selecting and maintaining a diverse T-cell repertoireQ33783983
Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infectionQ33793153
The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infectionQ33904114
Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivoQ33924186
IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+ T cellsQ33930706
T-cell therapy of cytomegalovirus and human immunodeficiency virus infectionQ33944151
A potential role for interleukin-7 in T-cell homeostasisQ33945863
Isolation of T-cell tropic HTLV-III-like retrovirus from macaquesQ34049156
Impact of cytokines on replication in the thymus of primary human immunodeficiency virus type 1 isolates from infantsQ34342452
Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymusQ34347432
Interleukin-7: master regulator of peripheral T-cell homeostasis?Q34382929
Regulation of naïve and memory T-cell homeostasisQ34515843
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient miceQ36364066
Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytesQ36368207
Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cellsQ36369770
IL-7 is critical for homeostatic proliferation and survival of naive T cellsQ37113213
Effect of cytokines on HIV-induced depletion of thymocytes in vivoQ39540937
Interleukin-7 in plasma correlates with CD4 T-cell depletion and may be associated with emergence of syncytium-inducing variants in human immunodeficiency virus type 1-positive individualsQ39604683
Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotypeQ39685564
The immunology of exceptional individuals: the lesson of centenarians.Q40606515
Restoration of T-cell homeostasis after T-cell depletionQ41665917
Generation of functional thymocytes in the human adult.Q41672172
A genetic and viral load analysis of the simian immunodeficiency virus during the acute phase in macaques inoculated by the vaginal routeQ42672356
Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic functionQ43752423
Pilot study of the effects of intermittent interleukin-2 on human immunodeficiency virus (HIV)-specific immune responses in patients treated during recently acquired HIV infectionQ43833986
Plasma SIV RNA viral load determination by real-time quantification of product generation in reverse transcriptase-polymerase chain reactionQ44244285
MHC class I alleles influence set-point viral load and survival time in simian immunodeficiency virus-infected rhesus monkeysQ45731032
Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infectionQ45784847
Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremiaQ48023288
Changes in thymic function with age and during the treatment of HIV infectionQ59066353
IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primatesQ61943541
IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantationQ73549850
What limits immune reconstitution in HIV infection? Divergent tools converge on thymic functionQ74575765
Discrepant responses to triple combination antiretroviral therapy in advanced HIV diseaseQ74628330
Bax deficiency partially corrects interleukin-7 receptor alpha deficiencyQ78518638
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectbiochemistryQ7094
cell biologyQ7141
immunologyQ101929
Simian immunodeficiency virusQ1890246
P304page(s)973-979
P577publication date2003-10-02
P1433published inBloodQ885070
P1476titleElevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus-induced disease progression
Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus–induced disease progression
P478volume103

Reverse relations

cites work (P2860)
Q35774975A GMCSF and IL7 fusion cytokine leads to functional thymic-dependent T-cell regeneration in age-associated immune deficiency
Q41859080Dual mechanism of impairment of interleukin-7 (IL-7) responses in human immunodeficiency virus infection: decreased IL-7 binding and abnormal activation of the JAK/STAT5 pathway
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Q37452072Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys.
Q31066870Going wild: lessons from naturally occurring T-lymphotropic lentiviruses
Q34633434Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses
Q36399551Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.
Q41056209Interleukin 7 increases human immunodeficiency virus type 1 LAI-mediated Fas-induced T-cell death.
Q37267762Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells.
Q82855791Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway
Q34052601Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates
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Q36498174Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis
Q45406572T cell receptor excision circles (TRECs) analysis during acute intrarectal infection of cynomolgus monkeys with pathogenic chimeric simian human immunodeficiency virus.
Q35847795Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys
Q81653120To kill or be killed: how HIV exhausts the immune system