Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy

scientific article published in July 1997

Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1528-1157.1997.TB01462.X
P698PubMed publication ID9579902
P5875ResearchGate publication ID13703966

P2093author name stringFreese A
During MJ
Leone P
Kaplitt MG
O'Connor MJ
Abbey M
O'Connor WM
Langer D
P2860cites workA missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsyQ24308706
Localization of a gene for autosomal dominant nocturnal frontal lobe epilepsy to chromosome 20q 13.2Q28295745
Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutationQ34152888
Molecular analysis of neuronal physiology by gene transfer into neurons with herpes simplex virus vectorsQ36708223
GABA neurons in seizure disorders: a review of immunocytochemical studiesQ36930621
Reporter genes: application to the study of mammalian gene transcriptionQ37826420
Gene therapy for neurologic diseaseQ40769415
Adenosine: a potential mediator of seizure arrest and postictal refractorinessQ41102217
The functional relationship between antidromically evoked field responses of the dentate gyrus and mossy fiber reorganization in temporal lobe epileptic patientsQ41126675
Prospects for gene therapy in Parkinson's diseaseQ41159915
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Hyperexcitability associated with localizable lesions in epileptic patientsQ43460203
The herpes simplex virus amplicon: A new eucaryotic defective-virus cloning-amplifying vectorQ44397432
HSV-1 vector mediated neuronal gene delivery. Strategies for molecular neuroscience and neurologyQ45111676
Gene delivery into the brain using virus vectorsQ45773320
Adenovirus-mediated gene therapy of experimental gliomasQ45870226
A model system for in vivo gene transfer into the central nervous system using an adenoviral vectorQ48325479
Increasing volume of distribution to the brain with interstitial infusion: dose, rather than convection, might be the most important factorQ49038729
The pathophysiologic relationships between lesion pathology, intracranial ictal EEG onsets, and hippocampal neuron losses in temporal lobe epilepsyQ52208155
Isolation of a novel gene underlying batten disease, CLN3Q56804260
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide YQ59055743
P433issue7
P921main subjectgene therapyQ213901
vector-borne diseaseQ2083837
P304page(s)759-766
P577publication date1997-07-01
P1433published inEpilepsiaQ5382969
P1476titleDirect gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: implications for a gene therapy approach to epilepsy
P478volume38

Reverse relations

cites work (P2860)
Q54986717A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits.
Q44420155Adeno-associated virus-mediated aspartoacylase gene transfer to the brain of knockout mouse for canavan disease
Q43051288Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo
Q45869225Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease
Q45546897Efficient early and sustained transduction of human fetal mesencephalon using adeno-associated virus type 2 vectors.
Q92638804Epilepsy Benchmarks Area II: Prevent Epilepsy and Its Progression
Q45864623Novel targets for CNS gene therapy
Q33545312Restorative gene therapy approaches to Parkinson's disease
Q37021317The promise of gene therapy for the treatment of epilepsy
Q34997511Therapeutic epilepsy research: from pharmacological rationale to focal adenosine augmentation
Q39990727Treatment of Lennox-Gastaut syndrome: overview and recent findings
Q57020780Use of Precision-Cut Lung Slices as an Tool for Evaluating Viruses and Viral Vectors for Gene and Oncolytic Therapy
Q34446026Viral-based gene transfer to the mammalian CNS for functional genomic studies