Polyoma virus middle T antigen: meddler or mimic?

scientific article

Polyoma virus middle T antigen: meddler or mimic? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0966-842X(00)88866-6
P698PubMed publication ID7719637

P2093author name stringDilworth SM
P2860cites workBinding of 14-3-3 proteins to the protein kinase Raf and effects on its activationQ24319934
Activation of Raf-1 by 14-3-3 proteinsQ24324360
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.Q34181194
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.Q34345750
14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteinsQ35624026
Vaccinia virus growth factor stimulates tyrosine protein kinase activity of A431 cell epidermal growth factor receptorsQ36909038
Novel monoclonal antibodies that differentiate between the binding of pp60c-src or protein phosphatase 2A by polyomavirus middle T antigenQ38320715
Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.Q39481540
Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinaseQ40309214
How receptor tyrosine kinases activate Ras.Q40778358
Association of polyomavirus middle tumor antigen with 14-3-3 proteinsQ41453913
A biochemical function for ras--at lastQ41461721
Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc.Q41495165
Separation of host range from transformation functions of the hr-t gene of polyomavirusQ42800070
Polyoma virus middle T is essential for virus replication and persistence as well as for tumor induction in miceQ45876413
Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesisQ46587019
The hunt for Ras targetsQ59095565
Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinaseQ72186416
P433issue1
P304page(s)31-35
P577publication date1995-01-01
P1433published inTrends in MicrobiologyQ15265732
P1476titlePolyoma virus middle T antigen: meddler or mimic?
P478volume3

Reverse relations

cites work (P2860)
Q35884435A novel 39-kilodalton membrane protein binds GTP in polyomavirus-transformed cells.
Q42819325Activation and nuclear translocation of mitogen-activated protein kinases by polyomavirus middle-T or serum depend on phosphatidylinositol 3-kinase.
Q40936714Association between src-kinases and the polyoma virus oncogene middle T-antigen requires PP2A and a specific sequence motif
Q33649564Catalytically inactive protein phosphatase 2A can bind to polyomavirus middle tumor antigen and support complex formation with pp60(c-src).
Q34468798Cell transformation by the middle T-antigen of polyoma virus
Q40840271Changes in cytoskeletal organization in polyoma middle T antigen-transformed fibroblasts: involvement of protein phosphatase 2A and src tyrosine kinases
Q41032130Characterization of fatty acid synthase in cell lines derived from experimental mammary tumors
Q30453323Cytoplasmic death signal triggered by SRC-mediated phosphorylation of the adenovirus E4orf4 protein
Q39605634Effect on polyomavirus T-antigen function of mutations in a conserved leucine-rich segment of the DnaJ domain
Q42802732Effects of neoplastic transformation and teniposide (VM26) on protein kinase C isoform expression in rodent fibroblasts
Q53420593Formation of transformed endothelial cells in the absence of VEGFR-2/Flk-1 by Polyoma middle T oncogene.
Q39877608Functional interaction between the SH2 domain of Fyn and tyrosine 324 of hamster polyomavirus middle-T antigen
Q35023729Independent contributions of polyomavirus middle T and small T to the regulation of early and late gene expression and DNA replication
Q35000523Lessons in signaling and tumorigenesis from polyomavirus middle T antigen
Q39881001Multimerization of polyomavirus middle-T antigen.
Q35782155Neoplastic transformation of prostatic and urogenital epithelium by the polyoma virus middle T gene
Q52530471Polyomavirus middle T antigen as a probe for T cell antigen receptor-coupled signaling pathways.
Q41239646Selective activation of T cell kinase p56lck by Herpesvirus saimiri protein tip.
Q28364018ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation
Q28364022ShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigen
Q41647867Signalling by Src family kinases: lessons learnt from DNA tumour viruses
Q41018483Simian virus 40 as a vector: recombinant viruses expressing individual polyoma T antigens
Q33935137The hamster polyomavirus--a brief review of recent knowledge
Q38943407The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner.
Q41374895Virocrine transformation
Q39880346pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence

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