Quinocetone triggers oxidative stress and induces cytotoxicity and genotoxicity in human peripheral lymphocytes of both genders

scientific article published on 2 October 2012

Quinocetone triggers oxidative stress and induces cytotoxicity and genotoxicity in human peripheral lymphocytes of both genders is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JSFA.5891
P698PubMed publication ID23027643
P5875ResearchGate publication ID231742279

P50authorWei BaoQ39062394
P2093author name stringWei Yang
Hong Yan
Liegang Liu
Di Wang
Xiao Xiao
Ping Yao
Liping Hao
Juan Fu
Andreas K Nussler
P2860cites workCytokinesis-block micronucleus cytome assay.Q53548886
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DNA strand cleaving properties and hypoxia-selective cytotoxicity of 7-chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-dioxideQ35707721
Quinoxaline 1,4-dioxide: a versatile scaffold endowed with manifold activitiesQ36264741
Role of mitochondrial oxidative stress to explain the different longevity between genders: protective effect of estrogensQ36647456
DNA strand cleavage by the phenazine di-N-oxide natural product myxin under both aerobic and anaerobic conditionsQ39442841
ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells.Q39629620
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Investigation of quinocetone-induced genotoxicity in HepG2 cells using the comet assay, cytokinesis-block micronucleus test and RAPD analysisQ39814952
Antigenotoxicity and antimutagenicity of lycopene in HepG2 cell line evaluated by the comet assay and micronucleus testQ40036144
Synthesis and biological evaluation of new 2-arylcarbonyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives and their reduced analoguesQ40073415
Molecular mechanism of mutagenesis induced by olaquindox using a shuttle vector pSP189/mammalian cell systemQ40309463
Mode of Action of Quindoxin and Substituted Quinoxaline-di- N -Oxides on Escherichia coliQ40618501
Gender differences in steady-state levels of oxidative damage to DNA in healthy individualsQ40641705
Induction of micronuclei and sister chromatid exchanges by polycyclic and N-heterocyclic aromatic hydrocarbons in cultured human lymphocytesQ42276034
Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar ratsQ42936282
Age-related sex differences in glutathione peroxidase and oxidative DNA damage in a healthy Mexican populationQ43076174
Identification of the major metabolites of quinocetone in swine urine using ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometryQ43200852
A rice serine carboxypeptidase-like gene OsBISCPL1 is involved in regulation of defense responses against biotic and oxidative stressQ43515161
Physiological oxidative stress model: Syrian hamster Harderian gland-sex differences in antioxidant enzymes.Q43557683
Micronucleus formation by benzene, cyclophosphamide, benzo(a)pyrene, and benzidine in male, female, pregnant female, and fetal miceQ43599416
Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxideQ43735067
Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males.Q44340532
Enzyme-activated, hypoxia-selective DNA damage by 3-amino-2-quinoxalinecarbonitrile 1,4-di-N-oxideQ45148699
MNT and MutaMouse studies to define the in vivo dose response relations of the genotoxicity of EMS and ENU.Q45347709
Pu-erh black tea supplementation decreases quinocetone-induced ROS generation and oxidative DNA damage in Balb/c miceQ45817176
Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cellsQ46210778
Oxidative stress during stressful heat exposure and recovery in the North Sea eelpout Zoarces viviparus L.Q46878086
Relevance of apple consumption for protection against oxidative damage induced by hydrogen peroxide in human lymphocytes.Q50701252
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcytotoxicityQ246181
genotoxicityQ1009245
P304page(s)1317-1325
P577publication date2012-10-02
P1433published inJournal of the Science of Food and AgricultureQ2740606
P1476titleQuinocetone triggers oxidative stress and induces cytotoxicity and genotoxicity in human peripheral lymphocytes of both genders
P478volume93

Reverse relations

cites work (P2860)
Q53187323A two-year dietary carcinogenicity study of cyadox in Sprague-Dawley rats.
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Q64941626Genotoxic risk of quinocetone and its possible mechanism in in vitro studies.
Q46838526Identification of oxidative stress and responsive genes of HepG2 cells exposed to quinocetone, and compared with its metabolites
Q38829588ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line
Q42055936Mechanisms of the Testis Toxicity Induced by Chronic Exposure to Mequindox
Q55002066Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse.
Q39077905Physiologically based pharmacokinetic model for quinocetone in pigs and extrapolation to mequindox
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Q37623500Toxic metabolites, MAPK and Nrf2/Keap1 signaling pathways involved in oxidative toxicity in mice liver after chronic exposure to Mequindox

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