A two-year dietary carcinogenicity study of cyadox in Sprague-Dawley rats.

scientific article published on 25 April 2017

A two-year dietary carcinogenicity study of cyadox in Sprague-Dawley rats. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YRTPH.2017.04.011
P698PubMed publication ID28454720

P2093author name stringXu Wang
Zonghui Yuan
Menghong Dai
Jianwu Zhang
Qianying Liu
Zhixin Lei
Luqing Cui
Ihsan Awais
P2860cites workLong-term dose-dependent response of Mequindox on aldosterone, corticosterone and five steroidogenic enzyme mRNAs in the adrenal of male ratsQ28580582
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Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategiesQ33877024
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The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overviewQ38092120
Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo.Q39138541
Investigation of quinocetone-induced genotoxicity in HepG2 cells using the comet assay, cytokinesis-block micronucleus test and RAPD analysisQ39814952
A phase II evaluation of tirapazamine plus cisplatin in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: a Gynecologic Oncology Group studyQ40378020
Olaquindox and cyadox stimulate growth and decrease intestinal mucosal immunity of piglets orally inoculated with Escherichia coliQ42495047
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Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxideQ43735067
Enzyme-activated, hypoxia-selective DNA damage by 3-amino-2-quinoxalinecarbonitrile 1,4-di-N-oxideQ45148699
N-oxide reduction of quinoxaline-1,4-dioxides catalyzed by porcine aldehyde oxidase SsAOX1.Q45780040
Quinocetone triggers oxidative stress and induces cytotoxicity and genotoxicity in human peripheral lymphocytes of both gendersQ45808492
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Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cellsQ46210778
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Proliferative and nonproliferative lesions of the rat and mouse mammary, Zymbal's, preputial, and clitoral glandsQ48630763
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Evaluation of the safety of primary metabolites of cyadox: Acute and sub-chronic toxicology studies and genotoxicity assessment.Q53260802
Phase I trial of tirapazamine, cisplatin, and concurrent accelerated boost reirradiation in patients with recurrent head and neck cancerQ79757577
Subchronic oral toxicity study with cyadox in Wistar ratsQ80384421
A ninety-day oral toxicity study of a new type of processed gum arabic, from Acacia tree (Acacia senegal) exudates, in F344 ratsQ81415619
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A chronic toxicity study of cyadox in Wistar ratsQ82727247
Two generation reproduction and teratogenicity studies of feeding quinocetone fed to Wistar ratsQ83253266
Two generation reproduction and teratogenicity studies of feeding cyadox in Wistar ratsQ83295904
Deoxidation rates play a critical role in DNA damage mediated by important synthetic drugs, quinoxaline 1,4-dioxidesQ86608500
P407language of work or nameEnglishQ1860
P304page(s)9-22
P577publication date2017-04-25
P1433published inRegulatory Toxicology and PharmacologyQ2138805
P1476titleA two-year dietary carcinogenicity study of cyadox in Sprague-Dawley rats.
P478volume87

Reverse relations

cites work (P2860)
Q47384545Dietary exposure assessment of cyadox based on tissue depletion of cyadox and its major metabolites in pigs, chickens, and carp
Q52564660Mequindox Induced Genotoxicity and Carcinogenicity in Mice.
Q58768427The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats

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