Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis

scientific article published in January 1988

Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1044245292
P356DOI10.1038/331171A0
P8608Fatcat IDrelease_emvbkvwzzraijogf4dajotzpam
P698PubMed publication ID2448638
P5875ResearchGate publication ID20706772

P50authorRuurd van der ZeeQ44187705
P2093author name stringCohen IR
van Eden W
van Embden JD
Thole JE
Hensen EJ
Noordzij A
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type IIQ34600354
Therapeutic vaccination against adjuvant arthritis using autoimmune T cells treated with hydrostatic pressureQ34635952
Cloning and sequence analysis of a partial cDNA for chicken cartilage proteoglycan core proteinQ35616492
Genes for the major protein antigens of the leprosy parasite Mycobacterium lepraeQ36489115
Characterization, sequence determination, and immunogenicity of a 64-kilodalton protein of Mycobacterium bovis BCG expressed in escherichia coli K-12.Q37020037
Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycansQ37525926
Regulation of autoimmune disease physiological and therapeuticQ39480719
Adjuvant polyarthritis. IV. Induction by a synthetic adjuvant: immunologic, histopathologic, and other studiesQ43484251
The 65kDa antigen of mycobacteria-a common bacterial protein?Q44211256
Lines of T Lymphocytes Induce or Vaccinate Against Autoimmune ArthritisQ54503292
T lymphocyte clones illuminate pathogenesis and affect therapy of experimental arthritisQ69871775
T lymphocytes of rheumatoid arthritis patients show augmented reactivity to a fraction of mycobacteria cross-reactive with cartilageQ69884839
EXPERIMENTAL MODELS IN RHEUMATOID DISEASEQ76716659
P433issue6152
P407language of work or nameEnglishQ1860
P304page(s)171-173
P577publication date1988-01-01
P1433published inNatureQ180445
P1476titleCloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis
P478volume331

Reverse relations

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Q35106298Legionella pneumophila htpAB heat shock operon: nucleotide sequence and expression of the 60-kilodalton antigen in L. pneumophila-infected HeLa cells
Q67773781Limiting dilution analysis of proliferative T cell responses to mycobacterial 65-kDa heat-shock protein fails to show significant frequency differences between synovial fluid and peripheral blood of patients with rheumatoid arthritis
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Q33891710Major cytoplasmic membrane protein of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease
Q35838783Management of early inflammatory arthritis. Intervention with immunomodulatory agents: T cell vaccination
Q36947176Mapping of a visceral leishmaniasis-specific immunodominant B-cell epitope of Leishmania donovani Hsp70.
Q36561485Mapping of viral epitopes with prokaryotic expression products
Q40650026Mechanisms of autoimmunity and AIDS: prospects for therapeutic intervention
Q37577996Mechanisms of immune injury in rheumatoid arthritis: evidence for the involvement of T cells and heat-shock protein
Q37424674Mechanisms of resistance to autoimmune disease induced by T-cell vaccination
Q35630488Mediators of joint swelling and damage in rheumatoid arthritis and pristane induced arthritis
Q71489274Meloxicam: a potent inhibitor of adjuvant arthritis in the Lewis rat
Q26744562Modulation of Adjuvant Arthritis by Cellular and Humoral Immunity to Hsp65
Q33267344Modulation of T cell function by combination of epitope specific and low dose anticytokine therapy controls autoimmune arthritis
Q40268988Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein.
Q36964799Modulation of experimental autoimmunity: treatment of adjuvant arthritis by immunization with a recombinant vaccinia virus
Q45230023Modulation of pristane-induced arthritis by mycobacterial antigens
Q36741615Molecular analysis of the hsp (groE) operon of Leptospira interrogans serovar copenhageni
Q40901167Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction?
Q41064214Molecular chaperones and disease
Q40154124Molecular cloning and sequence analysis of the Sta58 major antigen gene of Rickettsia tsutsugamushi: sequence homology and antigenic comparison of Sta58 to the 60-kilodalton family of stress proteins
Q28486695Molecular cloning, characterization and purification of ornithine carbamoyltransferase from Mycobacterium bovis BCG
Q34293468Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein
Q33581522Molecular mimicry--hypothesis or reality?
Q40641469Molecular mimicry.
Q40384526Molecular mimicry: any role in the pathogenesis of spondyloarthropathies?
Q67539450Monoclonal antibody epitopes of mycobacterial 65-kD heat-shock protein defined by epitope scanning
Q37719163Multiple moonlighting functions of mycobacterial molecular chaperones
Q36974801Mycobacteria and human autoimmune disease: direct evidence of cross-reactivity between human lactoferrin and the 65-kilodalton protein of tubercle and leprosy bacilli
Q30986453Mycobacteria contain two groEL genes: the second Mycobacterium leprae groEL gene is arranged in an operon with groES.
Q47862561Mycobacterial heat-shock proteins as carrier molecules
Q47860650Mycobacterial heat-shock proteins as carrier molecules. II: The use of the 70-kDa mycobacterial heat-shock protein as carrier for conjugated vaccines can circumvent the need for adjuvants and Bacillus Calmette Guérin priming
Q36187616Mycobacterium tuberculosis expresses two chaperonin-60 homologs.
Q79902443Mycobacterium tuberculosis heat-shock protein 70 impairs maturation of dendritic cells from bone marrow precursors, induces interleukin-10 production and inhibits T-cell proliferation in vitro
Q35173119Myelin Specific, Autoaggressive T Cell Clones in the Normal Immune Repertoire: Their Nature and Their Regulation
Q67997140Natural antibodies to 65 kD mycobacterial heat shock protein in rats do not correlate with susceptibility for Mycobacterium tuberculosis induced adjuvant arthritis
Q36623081Novel therapies for rheumatoid arthritis
Q39366351Nucleoprotein Diet Ameliorates Arthritis Symptoms in Mice Transgenic for Human T-Cell Leukemia Virus Type I (HTLV-1)
Q35224967Nucleotide sequence analysis and seroreactivities of the 65K heat shock protein from Mycobacterium paratuberculosis.
Q40573132Oral desensitisation in rheumatoid arthritis
Q47937510Oral dosing of rats with OM-89 results in the appearance of specific OM-89 antibodies of the IgG2a isotype: possible significance in the treatment of rheumatoid arthritis
Q77627766Oral tolerance and the treatment of rheumatoid arthritis
Q33683196Oral tolerance: mechanisms and therapeutic applications.
Q36677790Outer membrane protein PhoE as a carrier for the exposure of foreign antigenic determinants at the bacterial cell surface
Q33566939PPD and hsp65 induced monoarthritis initiates spontaneous recurrent flares in Lewis rats
Q36647506Pathogenesis of rheumatoid arthritis: its relevance to therapy in the '90s
Q38211102Pathogenetic mechanisms in the Mycoplasma arthritidis polyarthritis of rats
Q53496211Peptide competition at the level of MHC-binding sites using T cell clones from a rheumatoid arthritis patient
Q42610681Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid
Q36084456Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis
Q40391200PhoE protein as a carrier for foreign epitopes
Q34001526Plasma membrane expression of heat shock protein 60 in vivo in response to infection
Q41699482Possible mechanisms of chronic leprosy-related arthritis
Q40832886Possible role of bacterial heat-shock proteins in autoimmune diseases.
Q34204710Potential T cell epitopes of Mycobacterium tuberculosis that can instigate molecular mimicry against host: implications in autoimmune pathogenesis
Q41681096Presence of hsp65 in bacterial extracts (OM-89): a possible mediator of orally-induced tolerance?
Q67531351Prevention of adjuvant arthritis in rats by a nonapeptide from the 65-kD mycobacterial heat shock protein: specificity and mechanism
Q46730648Prevention of adjuvant arthritis in rats by a nonapeptide from the 65-kD mycobacterial heat-shock protein
Q35368485Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by antisense oligonucleotide treatment
Q77969613Preventive administration of Mycobacterium tuberculosis 10-kDa heat shock protein (hsp10) suppresses adjuvant arthritis in Lewis rats
Q24633077Primary structure of a human mitochondrial protein homologous to the bacterial and plant chaperonins and to the 65-kilodalton mycobacterial antigen
Q45751279Priming of CD8+ CTL effector cells in mice by immunization with a stress protein-influenza virus nucleoprotein fusion molecule
Q73085686Pristane-induced arthritis is CD4+ T-cell dependent
Q40808132Processing of self-proteins and its impact on shaping the T cell repertoire, autoimmunity and immune regulation
Q68119835Proliferation of peripheral blood mononuclear cells from rheumatoid arthritis patients to mycobacterial antigens
Q41512504Proliferative response of synovial fluid and peripheral blood mononuclear cells to arthritogenic and non-arthritogenic microbial antigens and to the 65-kDa mycobacterial heat-shock protein
Q33775679Prolonged survival of allografts induced by mycobacterial Hsp70 is dependent on CD4+CD25+ regulatory T cells.
Q40968027Prospects of immunotherapy for rheumatoid arthritis
Q54247025Protection against autoimmune disease by bacterial agents. II. PPD and pertussis toxin as proteins active in protecting mice against experimental autoimmune encephalomyelitis.
Q36356674Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein
Q34529369Protective role for heat shock protein-reactive alpha beta T cells in murine yersiniosis
Q36962262Purification and immunological characterization of a GroEL-like protein from Bordetella pertussis.
Q33561442Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis.
Q40954990Ras Signaling Inhibitors Attenuate Disease in Adjuvant-Induced Arthritis via Targeting Pathogenic Antigen-Specific Th17-Type Cells
Q44460303Reaction of antibody to mycobacterial 65 kDa heat-shock protein with human chondrocytes
Q35838706Reactive arthritis: the role of bacterial antigens in inflammatory arthritis
Q42008209Recognition of a Peptide Antigen by Heat Shock--reactive γδ T Lymphocytes
Q36350743Recognition of a mycobacteria-specific epitope in the 65-kD heat-shock protein by synovial fluid-derived T cell clones
Q41367393Recognition of a unique peptide epitope of the mycobacterial and human heat shock protein 65-60 antigen by T cells of patients with recurrent oral ulcers
Q83856664Recognition of heat shock protein 60 epitopes in children with type 1 diabetes
Q73950863Reduction of disease causative T-cells in experimental autoimmune disease models by a new antirheumatic drug, TAK-603
Q36662480Regulation of autoimmune arthritis by the pro-inflammatory cytokine interferon-gamma
Q37449469Regulation of mycobacterial heat-shock protein-reactive T cells by HLA class II molecules: lessons from leprosy
Q28469043Regulation of peripheral inflammation by spinal p38 MAP kinase in rats
Q52243845Regulation of self-major histocompatibility complex reactive human T-cell clones
Q36203550Regulatory T cells in autoimmune diseases: anti-ergotypic T cells
Q73486496Relationship between disease severity and responses by blood mononuclear cells from patients with rheumatoid arthritis to human heat-shock protein 60
Q43430085Relationships between the onset of pustulosis palmaris et plantaris, periodontitis and bacterial heat shock proteins
Q41514763Response of synovial fluid T cell clones to Yersinia enterocolitica antigens in patients with reactive Yersinia arthritis
Q72081832Restricted T cell receptor expression by human T cell clones specific for mycobacterial 65‐kDa heat‐shock protein: Selective in vivo expansion of T cells bearing defined receptors
Q44512203Restricted expression of T cell receptor V beta but not V alpha genes in rheumatoid arthritis
Q36700554Rheumatoid arthritis is linked to Proteus--the evidence
Q39543149Rheumatoid arthritis, mycobacterial antigens and agalactosyl IgG.
Q77650347Rodent models of arthritis: relevance for human disease
Q99725709Role of Infections in the Pathogenesis of Rheumatoid Arthritis: Focus on Mycobacteria
Q40699345Role of alpha/beta T and gamma/delta T cells in innate and acquired immunity
Q35532723Role of class I molecules of the major histocompatibility complex in cytotoxic T-cell function in health and disease
Q33975393Role of heat shock proteins in protection from and pathogenesis of infectious diseases.
Q37449539Role of hsp60 during autoimmune and bacterial inflammation
Q40901158Role of protein glycosylation in immune regulation
Q57351508Role of the Bowel Flora for Development of Immunity to hsp 65 and Arthritis in Three Experimental Models
Q36076495Self heat-shock protein 65-mediated regulation of autoimmune arthritis
Q67898364Self-reactive T cells are activated by the 65-kDa mycobacterial heat-shock protein in neonatally thymectomized mice
Q67998397Self-reactive and antigen-specific T cell clones derived from a HLA-DR4+/DR5+ donor: T cell receptors and MHC-restriction patterns
Q41492327Serum antibodies from patients with ankylosing spondylitis and Reiter's syndrome are reactive with HLA-B27 cells transfected with the Mycobacterium tuberculosis hsp60 gene
Q83459567Serum heat shock protein 60 can predict remission of flare-up in juvenile idiopathic arthritis
Q38302901Specificity of antibodies induced after immunization of mice with the mycobacterial heat shock protein of 65 kD.
Q33579431Staphylococcus aureus nasal carriage in rheumatoid arthritis: antibody response to toxic shock syndrome toxin-1.
Q37370206Stimulation of suppressive T cell responses by human but not bacterial 60-kD heat-shock protein in synovial fluid of patients with rheumatoid arthritis
Q41505426Stimulation of synovial fluid mononuclear cells with the human 65-kD heat shock protein or with live enterobacteria leads to preferential expansion of TCR-gamma delta+ lymphocytes
Q36356657Streptococcal cell wall arthritis. Passive transfer of disease with a T cell line and crossreactivity of streptococcal cell wall antigens with Mycobacterium tuberculosis
Q68628883Stress proteins and the immune response
Q39548332Stress proteins and the immune response to mycobacteria--antigens as virulence factors?
Q36203554Stress proteins as inducers and targets of regulatory T cells in arthritis
Q73451205Stress proteins as targets for anti-inflammatory therapies
Q41951334Stress proteins, self defence, and the myocardium
Q46750382Stress response of Porphyromonas gingivalis
Q36856283Stress, heat shock proteins, and autoimmunity: how immune responses to heat shock proteins are to be used for the control of chronic inflammatory diseases
Q28265877Structure and expression of the three MHC-linked HSP70 genes
Q48021071Successful primate immunization with peptides conjugated to purified protein derivative or mycobacterial heat shock proteins in the absence of adjuvants
Q71785378Suppression of adjuvant arthritis in rats by induction of oral tolerance to mycobacterial 65-kDa heat shock protein
Q67687885Surface expression by mononuclear phagocytes of an epitope shared with mycobacterial heat shock protein 60
Q57351824Synovial Cells Responding to a 65-kDa Mycobacterial Heat Shock Protein have a High Proportion of a TcRgammadelta Subtype Uncommon in Peripheral Blood
Q44639755Synovial fluid T cell reactivity against 65 kD heat shock protein of mycobacteria in early chronic arthritis
Q37897015Synovial fluid antigen-presenting cells unmask peripheral blood T cell responses to bacterial antigens in inflammatory arthritis
Q41164543Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells
Q36978250Synthesis of a select group of proteins by Neisseria gonorrhoeae in response to thermal stress
Q38665396Synthetic T and B cell recognition sites: implications for vaccine development
Q46264402T Cell-Mediated Chronic Inflammatory Diseases Are Candidates for Therapeutic Tolerance Induction with Heat Shock Proteins
Q41716909T cell lines responding to Mycoplasma arthritidis and chondrocytes in the Mycoplasma arthritidis infection of rats
Q67690210T cell reactivity to an epitope of the mycobacterial 65-kDa heat-shock protein (hsp 65) corresponds with arthritis susceptibility in rats and is regulated by hsp 65-specific cellular responses
Q37981258T cell regulation in autoimmune arthritis: possibilities for immunological intervention
Q40787117T cell repertoire and autoimmune diseases
Q41221348T cells from rejected human kidney allografts respond to heat shock protein 72.
Q35613694T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins
Q51835996T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors.
Q36560102T-Cells, Stress Proteins, and Pathogenesis of Mycobacterial Infections
Q40541780T-cell antigen receptors in rheumatoid arthritis
Q41540726T-cell reactivity to human HSP60 in oligo-articular juvenile chronic arthritis is associated with a favorable prognosis and the generation of regulatory cytokines in the inflamed joint
Q37449436T-cell recognition of bacterial heat-shock proteins in inflammatory arthritis
Q52313702THE ROLE OF AUTOIMMUNE REACTIVITY INDUCED BY HEAT SHOCK PROTEIN 70 IN THE PATHOGENESIS OF ESSENTIAL HYPERTENSION.
Q40095092Targeting of tolerogenic dendritic cells towards heat shock proteins: a novel therapeutic strategy for autoimmune diseases?
Q38179171Temporal cytokine expression and the target organ attributes unravel novel aspects of autoimmune arthritis
Q36725438The 65 KD Heat Shock Protein: A Key Molecule Mediating the Development of Autoimmune Arthritis?
Q36924516The 65-kDa heat-shock protein in the pathogenesis, prevention and therapy of autoimmune arthritis and diabetes mellitus in rats and mice
Q47153453The Enigma of Heat Shock Proteins in Immune Tolerance
Q47101711The Immunomodulatory Potential of tolDCs Loaded with Heat Shock Proteins
Q37578673The Mechanisms Underlying Chronic Inflammation in Rheumatoid Arthritis from the Perspective of the Epigenetic Landscape.
Q42150391The Role of M. leprae Hsp65 Protein and Peptides in the Pathogenesis of Uveitis.
Q42146676The anti-inflammatory mechanisms of Hsp70
Q44416332The arthritogenic properties of microbial antigens. Their implications in disease states
Q35347212The cellular immune response to heat shock proteins
Q40304964The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis
Q41450404The cytotoxic analysis of T cell receptor V delta 1+ T cell lines derived from the synovial fluid of rheumatoid arthritis patients
Q38979165The danger from within: alarmins in arthritis
Q37350868The determinants of susceptibility/resistance to adjuvant arthritis in rats
Q81280209The dynamics of articular leukocyte trafficking and the immune response to self heat-shock protein 65 influence arthritis susceptibility
Q35840722The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challenge
Q37908837The heat shock protein response and its role in inflammatory disease
Q36923494The immune-hypothalamo-pituitary-adrenal axis and autoimmunity
Q36079214The involvement of heat-shock proteins in the pathogenesis of autoimmune arthritis: a critical appraisal
Q38211100The mycobacterial 65 kD heat-shock protein and autoimmune arthritis.
Q73129008The preventive effects of incomplete Freund's adjuvant and other vehicles on the development of adjuvant-induced arthritis in Lewis rats
Q36355535The recombinant 65-kD heat shock protein of Mycobacterium bovis Bacillus Calmette-Guerin/M. tuberculosis is a target molecule for CD4+ cytotoxic T lymphocytes that lyse human monocytes
Q24799403The role and clinical implications of G6PI in experimental models of rheumatoid arthritis
Q39538513The role of IgG glycoforms in the pathogenesis of rheumatoid arthritis
Q37886317The role of gamma delta T cells in the normal and disordered immune system
Q35351365The role of heat shock protein in the persistence of arthritis
Q41514346The role of heat shock protein, microbial and autoimmune agents in the aetiology of Behçet's disease
Q35940078The role of immune tolerance in preventing and treating arthritis
Q41479027The role of molecular chaperones in mitochondrial protein import and folding
Q58827047The role of oil and agalactosyl IgG in the induction of arthritis in rodent models
Q72179257The roles of the hypothalamus and the gastrointestinal tract in the prevention of inflammatory autoimmune disease
Q73537458The route of administration of an immunodominant peptide derived from heat-shock protein 65 dramatically affects disease outcome in pristane-induced arthritis
Q53163526Therapeutic effect of an altered peptide ligand derived from heat-shock protein 60 by suppressing of inflammatory cytokines secretion in two animal models of rheumatoid arthritis.
Q72180821Time course of antibodies against IgG and type II collagen in adjuvant arthritis. Role of mycobacteria administration in antibody production
Q37157936Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responses
Q49073427Tracking antigen-specific human T lymphocytes in rheumatoid arthritis by T cell receptor analysis.
Q67657519Treatment of adjuvant arthritis in rats: Vaccination potential of a synthetic nonapeptide from the 65 kDa heat shock protein of mycobacteria
Q67727026Treatment of rats with monoclonal anti-CD4 induces long-term resistance to streptococcal cell wall-induced arthritis
Q41623175Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis
Q35096081Use of recombinant antigens expressed in Escherichia coli K-12 to map B-cell and T-cell epitopes on the immunodominant 65-kilodalton protein of Mycobacterium bovis BCG.
Q44740942Use of the enterobacterial outer membrane protein PhoE in the development of new vaccines and DNA probes.
Q37476298Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.
Q36117086Vaccination against tuberculosis and leprosy
Q35422849Vaccination with recombinant heat shock protein 60 from Histoplasma capsulatum protects mice against pulmonary histoplasmosis
Q38760986What can we learn about rheumatoid arthritis from animal models?
Q33565368Yersinia associated arthritis in SHR rats: effect of the microbial status of the host
Q73940574[Heat shock proteins or "stress proteins"]

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