Induction of antigen-specific CD4+ HLA-DR-restricted cytotoxic T lymphocytes as well as nonspecific nonrestricted killer cells by the recombinant mycobacterial 65-kDa heat-shock protein

scientific article published on February 1, 1990

Induction of antigen-specific CD4+ HLA-DR-restricted cytotoxic T lymphocytes as well as nonspecific nonrestricted killer cells by the recombinant mycobacterial 65-kDa heat-shock protein is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.1830200221
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Feji.1830200221
https://onlinelibrary.wiley.com/doi/full/10.1002/eji.1830200221
P698PubMed publication ID1690136

P2093author name stringJ. E. Thole
T. H. Ottenhoff
R. Kiessling
P. Pisa
J. D. Van Embden
D. S. Kumararatne
A. Wondimu
B. K. Ab
P2860cites workStress proteins are immune targets in leprosy and tuberculosisQ33580876
T cell epitopes on the 36K and 65K Mycobacterium leprae antigens defined by human T cell clonesQ34405014
Genes for the major protein antigens of Mycobacterium tuberculosis: the etiologic agents of tuberculosis and leprosy share an immunodominant antigenQ34606350
Use of recombinant antigens expressed in Escherichia coli K-12 to map B-cell and T-cell epitopes on the immunodominant 65-kilodalton protein of Mycobacterium bovis BCG.Q35096081
The 65-kilodalton antigen of Mycobacterium tuberculosisQ36230654
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activityQ36348121
The recombinant 65-kD heat shock protein of Mycobacterium bovis Bacillus Calmette-Guerin/M. tuberculosis is a target molecule for CD4+ cytotoxic T lymphocytes that lyse human monocytesQ36355535
Intra- and extracellular susceptibility of Mycobacterium avium-intracellulare complex to aminoglycoside antibioticsQ36610973
Purification, partial characterization, and identification of a skin-reactive protein antigen of Mycobacterium bovis BCG.Q37015585
Characterization of antibody-reactive epitopes on the 65-kilodalton protein of Mycobacterium lepraeQ37017949
Characterization, sequence determination, and immunogenicity of a 64-kilodalton protein of Mycobacterium bovis BCG expressed in escherichia coli K-12.Q37020037
Efficient mapping of protein antigenic determinantsQ37399826
CD8+ T lymphocytes in intracellular microbial infectionsQ39610609
Function and antigen recognition pattern of L3T4+ T-cell clones from Mycobacterium tuberculosis-immune miceQ40161640
A role for heat shock proteins in inflammation?Q40786592
A recombinant 64 kilodalton protein of Mycobacterium bovis bacillus Calmette-Guerin specifically stimulates human T4 clones reactive to mycobacterial antigensQ41815508
Listeria monocytogenes-reactive T lymphocyte clones with cytolytic activity against infected target cellsQ41828204
Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytesQ41845609
Processing of a minimal antigenic peptide alters its interaction with MHC moleculesQ42074478
T cells against a bacterial heat shock protein recognize stressed macrophagesQ42647400
Detection of tumour necrosis factor from lipopolysaccharide-stimulated human mononuclear cells by enzyme-linked immunosorbent assay and cytotoxicity bioassayQ44190036
The 65kDa antigen of mycobacteria-a common bacterial protein?Q44211256
Cellular, humoral, and gamma interferon responses to Mycobacterium leprae and BCG antigens in healthy individuals exposed to leprosyQ44547563
Mycobacterium leprae-specific protein antigens defined by cloned human helper T cellsQ45135493
Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritisQ45822620
Human T-cell clones recognize a major M. leprae protein antigen expressed in E. coliQ59087621
Mycobacteria-reactive Lyt-2+ T cell linesQ69020026
DR3-restricted T cells from different HLA-DR3-positive individuals recognize the same peptide (amino acids 2-12) of the mycobacterial 65-kDa heat-shock proteinQ69120346
Stress proteins may provide a link between the immune response to infection and autoimmunityQ69138830
Results of a World Health Organization-sponsored workshop on monoclonal antibodies to Mycobacterium lepraeQ69382645
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
cytotoxicityQ246181
immunologic cytotoxicityQ60345185
P304page(s)369-377
P577publication date1990-02-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleInduction of antigen-specific CD4+ HLA-DR-restricted cytotoxic T lymphocytes as well as nonspecific nonrestricted killer cells by the recombinant mycobacterial 65-kDa heat-shock protein
P478volume20

Reverse relations

cites work (P2860)
Q34548964An HLA-DRw53-restricted T-cell epitope from a novel Mycobacterium leprae protein antigen important to the human memory T-cell repertoire against M. leprae
Q33997723CD4-positive and CD8-positive cytotoxic T lymphocytes contribute to human papillomavirus type 16 E6 and E7 responses
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Q72344528Cellular and humoral immune responses to recombinant 65-kD antigen of Mycobacterium leprae in leprosy patients and healthy controls
Q54309397Enhancement of monocyte antimycobacterial activity by diethyldithiocarbamate (DTC)
Q40830503Heat shock (stress) proteins and autoimmunity in rheumatic diseases
Q36924511Heat shock proteins and autoimmunity in humans
Q36970606Heat shock proteins in immunopathology
Q37124489Heat-shock proteins and the gamma delta T cell response in virus infections: implications for autoimmunity
Q33617454Human T cells recognize mycobacterial heat shock proteins in the context of multiple HLA-DR molecules: studies with healthy subjects vaccinated with Mycobacterium bovis BCG and Mycobacterium leprae
Q68467814Human suppressor T cell clones lack CD28
Q44920257IFN-gamma regulates Fas ligand expression in human CD4+ T lymphocytes and controls their anti-mycobacterial cytotoxic functions
Q73191991Increased expression of Fas ligand on Mycobacterium tuberculosis infected macrophages: a potential novel mechanism of immune evasion by Mycobacterium tuberculosis?
Q27027110Innovative Strategies to Identify M. tuberculosis Antigens and Epitopes Using Genome-Wide Analyses
Q77579741Interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) are necessary in the early stages of induction of CD4 and CD8 cytotoxic T cells by Mycobacterium leprae heat shock protein (hsp) 65 kD
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