Modulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter

scientific article published in July 2000

Modulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1019906897
P356DOI10.1038/SJ.GT.3301231
P698PubMed publication ID10918491
P5875ResearchGate publication ID12400436

P2093author name stringRigal D
Divita G
Baggetto LG
Bernaud J
Marthinet E
P2860cites workModulation of multidrug resistance by verapamil or mdr1 anti-sense oligodeoxynucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human carcinoma (LoVo) line.Q54313706
Non-radioisotopic AFLP method using PCR primers fluorescently labeled with Cy5Q57220600
The mdrl gene, responsible for multidrug-resistance, codes for P-glycoproteinQ58449756
Efficient purification and reconstitution of P-glycoprotein for functional and structural studiesQ71763325
Overcoming multidrug resistance in human tumor cells using free and liposomally encapsulated antisense oligodeoxynucleotidesQ72211702
Cellular uptake and intracellular fate of antisense oligonucleotidesQ75294069
Intracellular localization of oligonucleotides: influence of fixative protocolsQ77227625
Modulation of estrogen receptor gene expression in human breast cancer cells: a decoy strategy with specific PCR-generated DNA fragmentsQ77425702
Selective reversal of drug resistance in drug-resistant lung adenocarcinoma cells by tumor-specific expression of mdrl ribozyme gene mediated by retrovirusQ81825944
Isolation and expression of a complementary DNA that confers multidrug resistanceQ24295219
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell lineQ24338329
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding foldQ24556499
The "initiator" as a transcription control elementQ29619589
Specific regulation of gene expression by antisense, sense and antigene nucleic acidsQ33256068
Binding protein-dependent transport systemsQ34030447
Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistanceQ34161314
A conserved downstream element defines a new class of RNA polymerase II promotersQ38287842
Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. gene-specific inhibition of tumor growthQ38329699
Transcriptional regulation of the human proenkephalin gene by conformational switching: implications for decoy designQ38337532
A new peptide vector for efficient delivery of oligonucleotides into mammalian cells.Q38344289
Progress in antisense oligonucleotide therapeuticsQ38363412
A novel potent strategy for gene delivery using a single peptide vector as a carrierQ39728864
Pharmacologic circumvention of multidrug resistanceQ40535280
Inactivation of MED-1 elements in the TATA-less, initiator-less mouse thymidylate synthase promoter has no effect on promoter strength or the complex pattern of transcriptional start sitesQ40965649
Identification of cis-elements of the human endothelin-A receptor gene and inhibition of the gene expression by the decoy strategyQ41032627
Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-rasQ41192006
Differential utilization of multiple transcription start points accompanies the overexpression of the P-glycoprotein-encoding gene in Chinese hamster lung cellsQ41349156
Effect of unmodified triple helix-forming oligodeoxyribonucleotide targeted to human multidrug-resistance gene mdr1 in MDR cancer cellsQ41436576
Biochemical, genetic, and metabolic adaptations of tumor cells that express the typical multidrug-resistance phenotype. Reversion by new therapiesQ41654976
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivativeQ41666601
Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular diseaseQ45887776
Secondary structure of P-glycoprotein investigated by circular dichroism and amino acid sequence analysisQ47961866
In vitro and in vivo reversal of cancer cell multidrug resistance by the semi-synthetic antibiotic tiamulin.Q54118345
Improvement of hammerhead ribozymes cleaving mdr-1 mRNA.Q54174765
Modulation of P-glycoprotein-mediated multidrug resistance by monoclonal antibodies, immunotoxins or antisense oligodeoxynucleotides in kidney carcinoma and normal kidney cells.Q54237546
Identification of a functional initiator sequence in the human MDR1 promoter.Q54247377
P433issue14
P921main subjectmultiple drug resistanceQ643839
P304page(s)1224-1233
P577publication date2000-07-01
P1433published inGene TherapyQ15763095
P1476titleModulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter
P478volume7

Reverse relations

cites work (P2860)
Q39590850A simple and fast microfluidic approach of same-single-cell analysis (SASCA) for the study of multidrug resistance modulation in cancer cells
Q37615342Chemically modified cell-penetrating peptides for the delivery of nucleic acids
Q40507972Complete reversal of multidrug resistance by stable expression of small interfering RNAs targeting MDR1.
Q40756238Cytogenetic characterization of chromosomal rearrangement in a human vinblastine-resistant CEM cell line: use of comparative genomic hybridization and fluorescence in situ hybridization
Q40722578Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2.
Q34448371Multidrug resistance in uveal melanoma
Q24562993New invMED1 element cis-activates human multidrug-related MDR1 and MVP genes, involving the LRP130 protein
Q30453423Real time dynamic imaging and current targeted therapies in the war on cancer: a new paradigm
Q37010772Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies
Q40514562Reversal of P-glycoprotein-mediated multidrug resistance with small interference RNA (siRNA) in leukemia cells
Q44084390Reversing antibiotic resistance
Q33868054Reversing multidrug resistance by RNA interference through the suppression of MDR1 gene in human hepatoma cells
Q35567283Transcriptional regulation of ABC drug transporters
Q34816232Transcriptional regulators of the human multidrug resistance 1 gene: recent views
Q37230918Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

Search more.