Porcine toxicology studies of SCH 58500, an adenoviral vector for the p53 gene

scientific article

Porcine toxicology studies of SCH 58500, an adenoviral vector for the p53 gene is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/TOXSCI/65.2.256
P698PubMed publication ID11812930
P5875ResearchGate publication ID11546433

P2093author name stringEllen Evans
Nathaniel Collins
James S MacDonald
Christopher Horvath
Richard E Morrissey
James Patrick
Eileen A Snyder
P2860cites workWAF1, a potential mediator of p53 tumor suppressionQ27861121
p53 mutations in human cancersQ28302973
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumoursQ29547697
Cancer. p53, guardian of the genomeQ29615610
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6Q29622924
Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cellsQ35088549
p53 function and dysfunctionQ35721291
Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirusQ35861543
Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.Q37013182
Wild-type p53 is a cell cycle checkpoint determinant following irradiationQ37152060
How loops, beta sheets, and alpha helices help us to understand p53.Q40694267
Development and characterization of recombinant adenoviruses encoding human p53 for gene therapy of cancerQ41445691
Genetic mechanisms of tumor suppression by the human p53 geneQ41710706
Recombinant E1-deleted adenovirus-mediated gene therapy for cancer: efficacy studies with p53 tumor suppressor gene and liver histology in tumor xenograft modelsQ45886517
Inoculation of Pigs with Adenoviruses of ManQ59093780
Rodent nonclinical safety evaluation studies of SCH 58500, an adenoviral vector for the p53 geneQ64379227
Tumor suppressor genesQ72455787
Equal transcription of wild-type and mutant p53 using bicistronic vectors results in the wild-type phenotypeQ72785614
P433issue2
P921main subjectAdenoviridaeQ193447
P304page(s)256-265
P577publication date2002-02-01
P1433published inToxicological SciencesQ2446966
P1476titlePorcine toxicology studies of SCH 58500, an adenoviral vector for the p53 gene
P478volume65

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cites work (P2860)
Q40424880Adenoviral p53 gene transfer and gemcitabine in three patients with liver metastases due to advanced pancreatic carcinoma
Q33713324Cancer-induced expansion and activation of CD11b+ Gr-1+ cells predispose mice to adenoviral-triggered anaphylactoid-type reactions
Q64378490Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses
Q40528538Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats
Q33387265Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factor
Q64245487Rodents Versus Pig Model for Assessing the Performance of Serotype Chimeric Ad5/3 Oncolytic Adenoviruses
Q47353872Severe pulmonary pathology after intravenous administration of vectors in cirrhotic rats
Q45862533Titer determination of Ad5 in blood: a cautionary note
Q45873058Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys
Q45872936Unexpected pulmonary uptake of adenovirus vectors in animals with chronic liver disease
Q38734134cDNA microarray assays to evaluate immune responses following intracranial injection of baculoviral vectors in non-human primates

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