review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1002/HEP.29689 |
P8608 | Fatcat ID | release_x4h7vkacgjarjjhg7fixjptfsa |
P932 | PMC publication ID | 5906137 |
P698 | PubMed publication ID | 29194686 |
P50 | author | Sanda Win | Q89453719 |
P2093 | author name string | Jun Zhang | |
Neil Kaplowitz | |||
Tin Aung Than | |||
Christina Oo | |||
Robert Win Maw Min | |||
P2860 | cites work | FGF-21 as a novel metabolic regulator | Q24523933 |
A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria | Q24534841 | ||
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury | Q38291198 | ||
Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes | Q38594016 | ||
Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes | Q38603408 | ||
Mixed lineage kinase 3 deficient mice are protected against the high fat high carbohydrate diet-induced steatohepatitis. | Q38627620 | ||
Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS. | Q38700457 | ||
Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity | Q38911401 | ||
Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis | Q39731721 | ||
Inflammation Mediated by JNK in Myeloid Cells Promotes the Development of Hepatitis and Hepatocellular Carcinoma | Q40011787 | ||
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development | Q40045418 | ||
JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death | Q40138480 | ||
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates. | Q40327138 | ||
The role of MAP2 kinases and p38 kinase in acute murine liver injury models | Q41614993 | ||
Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1. | Q41749934 | ||
A stress signaling pathway in adipose tissue regulates hepatic insulin resistance | Q41811449 | ||
Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation | Q44163069 | ||
Antcin H Protects Against Acute Liver Injury Through Disruption of the Interaction of c-Jun-N-Terminal Kinase with Mitochondria. | Q45933968 | ||
Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor | Q46254405 | ||
c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity | Q46679597 | ||
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. | Q46808839 | ||
Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice | Q46924515 | ||
A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic. | Q50488654 | ||
TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. | Q53299056 | ||
Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. | Q54205999 | ||
The JNK signal transduction pathway | Q79781771 | ||
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis | Q82677113 | ||
Mechanisms of Acetaminophen Hepatotoxicity: Do We Need JNK for Cell Death? | Q87813408 | ||
FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response | Q24653481 | ||
Role of endoplasmic reticulum stress in drug-induced toxicity | Q26765518 | ||
Pathophysiological significance of c-jun N-terminal kinase in acetaminophen hepatotoxicity | Q26799194 | ||
Signal transduction by the JNK group of MAP kinases | Q28142592 | ||
Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1 | Q28207670 | ||
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases | Q28239642 | ||
JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity | Q28256254 | ||
A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches | Q28392033 | ||
A central role for JNK in obesity and insulin resistance | Q29619778 | ||
c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src. | Q30009024 | ||
c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice | Q30010257 | ||
c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity | Q33912798 | ||
Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice | Q34117033 | ||
The PPARα-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway | Q34143232 | ||
cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance | Q34285542 | ||
JNK regulation of hepatic manifestations of the metabolic syndrome | Q34348797 | ||
Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity | Q34364833 | ||
Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation. | Q34963377 | ||
The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury | Q35642533 | ||
Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury | Q35648831 | ||
Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice | Q35763021 | ||
Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation | Q35808753 | ||
Metabolic stress signaling mediated by mixed-lineage kinases | Q36002831 | ||
Critical role for mixed-lineage kinase 3 in acetaminophen-induced hepatotoxicity | Q36335609 | ||
Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo. | Q36526237 | ||
Inhibition of JNK mitochondrial localization and signaling is protective against ischemia/reperfusion injury in rats | Q36596206 | ||
Bile-acid-induced cell injury and protection | Q37157813 | ||
FGF21 regulates metabolism and circadian behavior by acting on the nervous system | Q37161082 | ||
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation | Q37330051 | ||
MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet | Q37476440 | ||
Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury. | Q37617674 | ||
The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation | Q37822076 | ||
Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria | Q38085856 | ||
The novel intracellular protein CREG inhibits hepatic steatosis, obesity, and insulin resistance | Q38288136 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2013-2024 | |
P577 | publication date | 2018-04-06 | |
P1433 | published in | Hepatology | Q15724398 |
P1476 | title | New insights into the role and mechanism of c-Jun-N-terminal kinase signaling in the pathobiology of liver diseases | |
P478 | volume | 67 |
Q93038072 | ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model |
Q55365441 | Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways. |
Q64108612 | Combined effects of ambient particulate matter exposure and a high-fat diet on oxidative stress and steatohepatitis in mice |
Q90226091 | Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells |
Q93122181 | Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury |
Q64973345 | Fibroblast growth factors 19 and 21 in acute liver damage. |
Q92243745 | Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat |
Q91302357 | Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway |
Q90382152 | Mitogen-Activated Protein Kinases (MAPKs) and Cholangiocarcinoma: The Missing Link |
Q98613138 | Oxidative stress in alcohol-related liver disease |
Q91892215 | SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition |
Q95856699 | The Protective Effects of Imperatorin on Acetaminophen Overdose-Induced Acute Liver Injury |
Q59792854 | The Regulation of JNK Signaling Pathways in Cell Death through the Interplay with Mitochondrial SAB and Upstream Post-Translational Effects |
Q89747950 | trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop |
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