Regulation of the pituitary-specific homeobox gene GHF1 by cell-autonomous and environmental cues.

scientific article published in June 1990

Regulation of the pituitary-specific homeobox gene GHF1 by cell-autonomous and environmental cues. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/345829A0
P698PubMed publication ID1972784

P2093author name stringKarin M
McCormick A
Brady H
Theill LE
P2860cites workA pituitary-specific trans-acting factor can stimulate transcription from the growth hormone promoter in extracts of nonexpressing cellsQ69054283
The molecular basis for metameric pattern in the Drosophila embryoQ114755591
A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequenceQ28247853
The pituitary-specific transcription factor GHF-1 is a homeobox-containing proteinQ28283838
[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reactionQ29544077
The rat serum albumin gene: analysis of cloned sequencesQ31169937
Structure and chromosomal localization of the functional intronless human JUN protooncogeneQ33680602
The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene winglessQ34166322
The Drosophila patched gene encodes a putative membrane protein required for segmental patterningQ34469429
Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitroQ37399225
Growth hormone gene regulation: a paradigm for cell-type-specific gene activationQ37915456
A regulatory hierarchy for cell specialization in yeastQ38241033
Homeo boxes in the study of developmentQ39462903
Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryosQ41230257
Stimulation of Adenosine 3′,5′-Monophosphate Production by Growth Hormone-Releasing Factor and Its Inhibition by Somatostatin in Anterior Pituitary Cellsin Vitro*Q42449219
Regulation and function of the Drosophila segmentation gene fushi tarazuQ42504179
Dissection of functional domains of the pituitary-specific transcription factor GHF-1.Q44258345
Identification of an adenosine 3',5'-monophosphate (cAMP)-responsive region in the rat growth hormone gene: evidence for independent and synergistic effects of cAMP and thyroid hormone on gene expressionQ45839715
Induction of human growth hormone promoter activity by the adenosine 3',5'-monophosphate pathway involves a novel responsive element.Q45984237
Extinction of growth hormone expression in somatic cell hybrids involves repression of the specific trans-activator GHF-1.Q46068708
A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patchedQ46395235
Oncogene jun encodes a sequence-specific trans-activator similar to AP-1.Q46795550
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotypeQ46821977
Transcriptional regulation of growth hormone gene expression by growth hormone-releasing factorQ48716014
Characterization of a growth hormone-releasing factor from a human pancreatic islet tumourQ48872563
Expression of GHF-1 protein in mouse pituitaries correlates both temporally and spatially with the onset of growth hormone gene activityQ49058843
Domain of Ultrabithorax expression in Drosophila visceral mesoderm from autoregulation and exclusion.Q52456510
Homoeo boxes, POU proteins and the limits to promiscuityQ58989608
Limbs: a pattern emergesQ59002707
Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formationQ59065602
Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryosQ59095446
P433issue6278
P407language of work or nameEnglishQ1860
P304page(s)829-832
P577publication date1990-06-01
P1433published inNatureQ180445
P1476titleRegulation of the pituitary-specific homeobox gene GHF1 by cell-autonomous and environmental cues.
P478volume345

Reverse relations

cites work (P2860)
Q41357884A dopamine-responsive domain in the N-terminal sequence of Pit-1. Transcriptional inhibition in endocrine cell types
Q33636310A model for the development of the hypothalamic-pituitary axis: transcribing the hypophysis
Q41431643A monomeric derivative of the cellular transcription factor CREB functions as a constitutive activator.
Q35071190A single base difference between Pit-1 binding sites at the hGH promoter and locus control region specifies distinct Pit-1 conformations and functions
Q38330572A transcriptional hierarchy involved in mammalian cell-type specification
Q42527597AP-1 and Oct-1 transcription factors down-regulate the expression of the human PIT1/GHF1 gene
Q38332872Activation of the prolactin gene by peroxisome proliferator-activated receptor-alpha appears to be DNA binding-independent
Q37324838Activin inhibits binding of transcription factor Pit-1 to the growth hormone promoter
Q83396662Analysis of polymorphism within POU1F1 gene in relation to milk production traits in dairy Sarda sheep breed
Q40408934Analysis of the rat hepatocyte nuclear factor (HNF) 1 gene promoter: synergistic activation by HNF4 and HNF1 proteins
Q88154480Association of pituitary specific transcription factor-1 (POU1F1) gene polymorphism with growth and biometric traits and blood metabolites in Iranian Zel and Lori-Bakhtiari sheep
Q30370587Associations of POU1F1 gene polymorphisms and protein structure changes with growth traits and blood metabolites in two Iranian sheep breeds.
Q42455474Autoregulation of eukaryotic transcription factors
Q38359267Autoregulatory loop in the regulation of the mammalian ftz-f1 gene
Q41464476C-type natriuretic peptide stimulates secretion of growth hormone from rat-pituitary-derived GH3 cells via a cyclic-GMP-mediated pathway
Q41545075Cell-type-specific function of the C-type natriuretic peptide gene promoter in rat anterior pituitary-derived cultured cell lines
Q42810482Characterization of transactivation domain and developmental expression of pituitary specific transcription factor, Pit-1 of ayu (Plecoglossus altivelis).
Q38302086Combined effect of mutations of the GH1 gene and its proximal promoter region in a child with growth hormone neurosecretory dysfunction (GHND).
Q37670107Constitutive somatostatin receptor subtype-3 signaling suppresses growth hormone synthesis
Q40500434Development and heterogeneity of prolactin cells
Q33218701Differential splicing of the GHF1 primary transcript gives rise to two functionally distinct homeodomain proteins
Q34052932Dissection of an indirect autoregulatory response of a homeotic Drosophila gene
Q36558790Distinct variant DNA-binding sites determine cell-specific autoregulated expression of the Drosophila POU domain transcription factor drifter in midline glia or trachea.
Q35634286Epstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activity
Q36683946Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro
Q38334375Function of the Homeodomain Protein GHF1 in Pituitary Cell Proliferation
Q41149770Function of the conserved Pit-1 gene distal enhancer in progenitor and differentiated pituitary cells
Q36551161Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain
Q28512102GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function
Q63412752Growth Hormone-Releasing Hormone: Discovery, Regulation, and Actions
Q41684439Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain
Q36698768Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein
Q89948381Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription
Q54360154Identification of mammalian Pit-1w, possibly involved in spermatogenesis in mice.
Q40405744Identification of proteins that interact with CREB during differentiation of F9 embryonal carcinoma cells
Q36270230Indirect autoregulation of a homeotic Drosophila gene mediated by extracellular signaling
Q41653264Inhibitory control of prolactin and Pit-1 gene promoters by dopamine. Dual signaling pathways required for D2 receptor-regulated expression of the prolactin gene
Q28567475LFB1/HNF1 acts as a repressor of its own transcription
Q41104128Lovastatin decreases prolactin and growth hormone gene expression in GH4C1 cells through a cAMP dependent mechanism
Q38288602M-phase-specific phosphorylation of the POU transcription factor GHF-1 by a cell cycle-regulated protein kinase inhibits DNA binding
Q36846687Molecular cloning of gilthead seabream (Sparus aurata) pituitary transcription factor GHF-1/Pit-1.
Q34084110Molecular determinants of pituitary cytodifferentiation
Q40017619Negative regulation of expression of the pituitary-specific transcription factor GHF-1/Pit-1 by thyroid hormones through interference with promoter enhancer elements
Q42457218Nuclear factor 1 regulates the distal silencer of the human PIT1/GHF1 gene
Q28508437Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoter
Q78083135Pit-1 mediates cell-specific and cAMP-induced transcription of the tilapia GH gene
Q39341389Pit-1w may regulate prolactin gene expression in mouse testis
Q42514753Pituitary alterations involved in the decline of growth hormone gene expression in the pituitary of aging rats
Q50973853Proline-rich-protein promoters direct LacZ expression to the granular convoluted tubular cells of the submandibular gland in adult transgenic mice.
Q89053710R-spondin1/Wnt-enhanced Ascl2 autoregulation controls the self-renewal of colorectal cancer progenitor cells
Q36735093Regulation and a possible stage-specific function of Oct-2 during pre-B-cell differentiation
Q41175204Role of Pit-1 in the gene expression of growth hormone, prolactin, and thyrotropin
Q35597350Role of a pituitary-specific transcription factor (pit-1/GHF-1) or a closely related protein in cAMP regulation of human thyrotropin-beta subunit gene expression
Q44768920Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant
Q41302742Synergistic transcriptional activation of the thyrotropin receptor promoter by cyclic AMP-responsive-element-binding protein and thyroid transcription factor 1
Q40411122The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.
Q40422397The molecular pathology of pituitary hormone deficiency and resistance
Q33283312The mouse proline-rich protein MP6 promoter binds isoprenaline-inducible parotid nuclear proteins via a highly conserved NFkB/rel-like site
Q36812290The restricted promoter activity of the liver transcription factor hepatocyte nuclear factor 3 beta involves a cell-specific factor and positive autoactivation
Q35107692The thyroid hormone receptor antagonizes CREB-mediated transcription
Q41594713The thyroid hormone response element is required for activation of the growth hormone gene promoter by nicotinamide analogs
Q38320406The transcription factor Pit-1/GHF-1 is expressed in hemopoietic and lymphoid tissues.
Q42522959Thyroid hormone receptor beta2 promoter activity in pituitary cells is regulated by Pit-1.
Q73019072Transcription factors coupled to the cAMP-signalling pathway
Q41636025Transcription factors in normal and neoplastic pituitary tissues
Q40614728Transcriptional control of gene expression by cAMP-response element binding proteins
Q36468791Transcriptional regulation by cAMP
Q35228808Transgenic approaches to modifying cell and tissue function
Q39637175Tumor-associated CpG demethylation augments hypoxia-induced effects by positive autoregulation of HIF-1α.
Q42464784cAMP responsiveness of the bovine calpastatin gene promoter
Q40372635cAMP-dependent regulation of gene transcription by cAMP response element-binding protein and cAMP response element modulator

Search more.