scholarly article | Q13442814 |
P50 | author | Kim L Powell | Q56845661 |
Christopher A Reid | Q56850335 | ||
Mastura Monif | Q81294421 | ||
P2093 | author name string | Megan L Smart | |
David A Williams | |||
P2860 | cites work | Interleukin 1 is processed and released during apoptosis | Q24315035 |
P2X7 receptor-Pannexin1 complex: pharmacology and signaling | Q24647580 | ||
Microglia and neuroinflammation: a pathological perspective | Q24799838 | ||
Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration | Q24815912 | ||
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo | Q27860578 | ||
Neuronal P2X7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems | Q28215870 | ||
Tissue distribution of the P2X7 receptor | Q28254153 | ||
Receptors for purines and pyrimidines | Q28283941 | ||
Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo | Q28506489 | ||
A plethora of presynaptic proteins associated with ATP-storing organelles in cultured astrocytes | Q28564872 | ||
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7) | Q28568856 | ||
Altered cytokine production in mice lacking P2X(7) receptors | Q28586061 | ||
ATP induces nucleotide permeability in rat mast cells | Q28678698 | ||
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex | Q30479449 | ||
Cytolytic P2X purinoceptors. | Q33592245 | ||
Reactive microgliosis | Q33604483 | ||
Dynamic selectivity filters in ion channels | Q33731015 | ||
Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin | Q33876996 | ||
Gain of function mutants: ion channels and G protein-coupled receptors | Q33938569 | ||
Extracellular ATP and P2X7 receptors in neurodegeneration | Q34768762 | ||
Prospects for rational development of pharmacological gap junction channel blockers | Q35007602 | ||
Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin | Q36376502 | ||
High Ca(2+)-phosphate transfection efficiency enables single neuron gene analysis | Q39128633 | ||
A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion | Q40412183 | ||
P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region | Q40681894 | ||
Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease. | Q40773870 | ||
Cytotoxicity of microglia | Q40870381 | ||
Volume loss of the hippocampus and temporal lobe in healthy elderly persons destined to develop dementia | Q40896306 | ||
Chemokines induce migration and changes in actin polymerization in adult rat brain microglia and a human fetal microglial cell line in vitro | Q40980153 | ||
Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis | Q41433234 | ||
Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor | Q41559800 | ||
Stimulation of Ca(2+) influx through ATP receptors on rat brain synaptosomes: identification of functional P2X(7) receptor subtypes | Q43263816 | ||
ATP mediates calcium signaling between astrocytes and microglial cells: modulation by IFN-gamma | Q43600966 | ||
Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. | Q43715908 | ||
Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus | Q44030451 | ||
Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration | Q44055767 | ||
Activation of presynaptic P2X7-like receptors depresses mossy fiber-CA3 synaptic transmission through p38 mitogen-activated protein kinase. | Q44067005 | ||
P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease | Q44292875 | ||
Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid | Q44325495 | ||
Differential co-localisation of the P2X7 receptor subunit with vesicular glutamate transporters VGLUT1 and VGLUT2 in rat CNS. | Q44714746 | ||
Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. | Q44723151 | ||
Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1 beta release from human monocytes | Q44788647 | ||
Increased morphological diversity of microglia in the activated hypothalamic supraoptic nucleus. | Q44895554 | ||
P2X7 receptor inhibition improves recovery after spinal cord injury | Q44982503 | ||
Effects of carbenoxolone on alveolar fluid clearance and lung inflammation in the rat. | Q45041330 | ||
Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors | Q46614579 | ||
Cellular localization of P2X7 receptor mRNA in the rat brain | Q46821425 | ||
Apoptotic pathways mobilized in microglia and neurones as a consequence of chromogranin A-induced microglial activation | Q48149106 | ||
Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. | Q48180638 | ||
Neurofibrillary tangles in nondemented elderly subjects and mild Alzheimer disease | Q48186602 | ||
Comparative MR analysis of the entorhinal cortex and hippocampus in diagnosing Alzheimer disease | Q48285881 | ||
Hippocampal and entorhinal cortex atrophy in frontotemporal dementia and Alzheimer's disease | Q48298121 | ||
Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes | Q48310232 | ||
Mechanisms of cell death in Alzheimer disease--immunopathology. | Q48330745 | ||
Development of microglia in the postnatal rat hippocampus | Q48344574 | ||
Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus | Q48378167 | ||
Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease | Q48394474 | ||
Morphology of reactive microglia in the injured cerebral cortex. Fractal analysis and complementary quantitative methods | Q48623708 | ||
Nonuniform distribution of Ca2+ channel subtypes on presynaptic terminals of excitatory synapses in hippocampal cultures | Q48728265 | ||
The P2X(7) receptor from Xenopus laevis: formation of a large pore in Xenopus oocytes | Q48865628 | ||
ATP4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes. | Q50902451 | ||
Co-release of noradrenaline and ATP from cultured sympathetic neurons. | Q51630641 | ||
Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner. | Q53278044 | ||
Microglia: Intrinsic immuneffector cell of the brain | Q56029409 | ||
New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neuron injury | Q68768348 | ||
[Microglia: origin and development] | Q74270494 | ||
Two different ionotropic receptors are activated by ATP in rat microglia | Q78157427 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | microglia | Q1622829 |
P304 | page(s) | 3781-3791 | |
P577 | publication date | 2009-03-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore | |
P478 | volume | 29 |
Q42455664 | 3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) disrupts blood-brain barrier integrity through a mechanism involving P2X7 receptors. |
Q59336312 | A central role for P2X7 receptors in human microglia |
Q47269263 | A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants. |
Q36303652 | ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor |
Q39143832 | ATP is required and advances cytokine-induced gap junction formation in microglia in vitro. |
Q37960756 | ATP receptors gate microglia signaling in neuropathic pain |
Q35748675 | ATP-P2X7 receptor signaling controls basal and TNFα-stimulated glial cell proliferation |
Q29994732 | Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors |
Q47915562 | Adaptive phenotype of microglial cells during the normal postnatal development of the somatosensory "Barrel" cortex. |
Q91938747 | Advances in the Potential Biomarkers of Epilepsy |
Q96289949 | Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia |
Q37468719 | Block of P2X7 receptors could partly reverse the delayed neuronal death in area CA1 of the hippocampus after transient global cerebral ischemia |
Q40594560 | CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy |
Q36515088 | CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. |
Q38182045 | Calcium ion influx in microglial cells: physiological and therapeutic significance |
Q35961235 | Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function |
Q52645864 | Coordinate effects of P2X7 and extracellular acidification in microglial cells. |
Q40074031 | Effect of naringin on gp120-induced injury mediated by P2X7 receptors in rat primary cultured microglia |
Q42374557 | Electroacupuncture ameliorating post-stroke cognitive impairments via inhibition of peri-infarct astroglial and microglial/macrophage P2 purinoceptors-mediated neuroinflammation and hyperplasia |
Q37906358 | Emerging role of extracellular nucleotides and adenosine in multiple sclerosis |
Q41461113 | Endogenous hydrogen sulphide attenuates NLRP3 inflammasome-mediated neuroinflammation by suppressing the P2X7 receptor after intracerebral haemorrhage in rats. |
Q35234329 | Estrogen and P2 Purinergic Receptor Systems in Microglia: Therapeutic Targets for Neuroprotection |
Q43425821 | Ethanol differentially modulates P2X4 and P2X7 receptor activity and function in BV2 microglial cells. |
Q34308005 | Experimental characterization and mathematical modeling of P2X7 receptor channel gating. |
Q37348492 | Expression of P2 nucleotide receptors varies with age and sex in murine brain microglia |
Q50438980 | Extracellular ATP differentially modulates Toll-like receptor 4-mediated cell survival and death of microglia. |
Q42316250 | Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells |
Q38870205 | Extracellular purines, purinergic receptors and tumor growth. |
Q41355158 | Functional characterization of mutants in the transmembrane domains of the rat P2X7 receptor that regulate pore conductivity and agonist sensitivity. |
Q51767986 | Genetic variation in P2RX7 and pain tolerance. |
Q37830727 | Glutamate and ATP signalling in white matter pathology |
Q92040409 | Immune mechanisms of stress susceptibility and resilience: Lessons from animal models |
Q49143369 | Increased Expression and Cellular Localization of P2X7R in Cortical Lesions of Patients With Focal Cortical Dysplasia |
Q34159466 | Increased Plp1 Gene Expression Leads to Massive Microglial Cell Activation and Inflammation Throughout the Brain |
Q43963291 | Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079. |
Q37720013 | Inhibiting purinergic P2X7 receptors with the antagonist brilliant blue G is neuroprotective in an intranigral lipopolysaccharide animal model of Parkinson's disease |
Q59128190 | Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice |
Q47736252 | Inhibition of P2X7 Receptor Ameliorates Nuclear Factor-Kappa B Mediated Neuroinflammation Induced by Status Epilepticus in Rat Hippocampus |
Q42274395 | Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus |
Q99248453 | Inhibition of purinergic P2X receptor 7 (P2X7R) decreases granulocyte-macrophage colony-stimulating factor (GM-CSF) expression in U251 glioblastoma cells |
Q35210209 | Inhibition of the P2X7 receptor reduces cystogenesis in PKD. |
Q27500422 | Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms |
Q27303076 | Interleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore. |
Q58701141 | Intrathecal delivery of a palmitoylated peptide targeting Y382-384 within the P2X7 receptor alleviates neuropathic pain |
Q41969599 | Involvement of P2X7 receptor in neuronal degeneration triggered by traumatic injury. |
Q92577404 | Involvement of the P2X7 receptor in the migration and metastasis of tamoxifen-resistant breast cancer: effects on small extracellular vesicles production |
Q90335558 | Ion channels as therapeutic antibody targets |
Q39154721 | Is pannexin the pore associated with the P2X7 receptor? |
Q91669522 | LPS-Induced Systemic Neonatal Inflammation: Blockage of P2X7R by BBG Decreases Mortality on Rat Pups and Oxidative Stress in Hippocampus of Adult Rats |
Q42487631 | Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease |
Q32185814 | Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor-Dependent Death of Retinal Endothelial Cells. |
Q52150882 | Mechanism of microglia neuroprotection: Involvement of P2X7, TNFα, and valproic acid. |
Q26864358 | Mechanisms and potential therapeutic applications of microglial activation after brain injury |
Q36842170 | Methamphetamine alters microglial immune function through P2X7R signaling |
Q36893695 | Microglia and ischemic stroke: a double-edged sword |
Q38148753 | Microglia control neuronal network excitability via BDNF signalling |
Q37003009 | Microglia dynamics and function in the CNS. |
Q50242326 | Microglia proliferation is controlled by P2X7 receptors in a Pannexin-1-independent manner during early embryonic spinal cord invasion. |
Q34587134 | Microglial P2X₇ receptor expression is accompanied by neuronal damage in the cerebral cortex of the APPswe/PS1dE9 mouse model of Alzheimer's disease |
Q37794381 | Microglial activation in stroke: therapeutic targets |
Q42722345 | Microglial zinc uptake via zinc transporters induces ATP release and the activation of microglia |
Q34002086 | Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional roles |
Q93079510 | Neurodegeneration and Neuro-Regeneration-Alzheimer's Disease and Stem Cell Therapy |
Q48113339 | Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift |
Q33799452 | Neuronal P2X7 receptor-induced reactive oxygen species production contributes to nociceptive behavior in mice |
Q38102686 | Neurotransmitter signaling in the pathophysiology of microglia |
Q89207621 | New role of P2X7 receptor in an Alzheimer's disease mouse model |
Q34158330 | Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers |
Q36079268 | Noninvasive molecular imaging of neuroinflammation |
Q41361968 | Nucleotide transmitters ATP and ADP mediate intercellular calcium wave communication via P2Y12/13 receptors among BV-2 microglia. |
Q26781625 | Nucleotides in neuroregeneration and neuroprotection |
Q38296527 | P2X and P2Y receptors—role in the pathophysiology of the nervous system |
Q28066934 | P2X ion channel receptors and inflammation |
Q38406301 | P2X purinoceptors as a link between hyperexcitability and neuroinflammation in status epilepticus |
Q26823175 | P2X receptors as targets for the treatment of status epilepticus |
Q41974044 | P2X receptors in neuroglia |
Q42265737 | P2X(7) Receptors in Neurological and Cardiovascular Disorders |
Q38103774 | P2X(7) receptors in cerebral ischemia |
Q38005032 | P2X4 purinoceptor signaling in chronic pain |
Q92799403 | P2X7 Interactions and Signaling - Making Head or Tail of It |
Q46479061 | P2X7 Receptor Signaling Contributes to Sepsis-Associated Brain Dysfunction |
Q42010874 | P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression |
Q97882908 | P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases |
Q37679001 | P2X7 antagonism using Brilliant Blue G reduces body weight loss and prolongs survival in female SOD1G93A amyotrophic lateral sclerosis mice. |
Q21285096 | P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia |
Q46322679 | P2X7 receptor antagonism prevents IL-1β release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy. |
Q38074161 | P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control. |
Q37355436 | P2X7 receptor inhibition increases CNTF in the subventricular zone, but not neurogenesis or neuroprotection after stroke in adult mice |
Q87720533 | P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage |
Q40811498 | P2X7 receptors and Fyn kinase mediate ATP-induced oligodendrocyte progenitor cell migration |
Q59321165 | P2X7 receptors are a potential novel target for anti-glioma therapies |
Q30524208 | P2X7 signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand |
Q87177486 | P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-α in cultured mouse microglia |
Q48531462 | Pathological potential of astroglial purinergic receptors |
Q48247387 | Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response |
Q38650165 | Pharmacological properties of the rhesus macaque monkey P2X7 receptor |
Q90263726 | Pleiotropic Roles of P2X7 in the Central Nervous System |
Q39033807 | Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks. |
Q90307991 | Post-Ischaemic Immunological Response in the Brain: Targeting Microglia in Ischaemic Stroke Therapy |
Q45755899 | Potentiation of inhibitory synaptic transmission by extracellular ATP in rat suprachiasmatic nuclei. |
Q28078621 | Precision Medicine in Multiple Sclerosis: Future of PET Imaging of Inflammation and Reactive Astrocytes |
Q36844881 | Purinergic receptors as potential therapeutic targets in Alzheimer's disease |
Q38653049 | Purinergic signaling and the functioning of the nervous system cells |
Q26822468 | Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death |
Q38869831 | Repeated Social Defeat, Neuroinflammation, and Behavior: Monocytes Carry the Signal. |
Q42650027 | Residues 155 and 348 contribute to the determination of P2X7 receptor function via distinct mechanisms revealed by single-nucleotide polymorphisms |
Q36850932 | Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways |
Q37599542 | Role of microglia in neuronal degeneration and regeneration |
Q35846494 | Roles of white matter in central nervous system pathophysiologies |
Q38679789 | Silencing of P2X7R by RNA interference in the hippocampus can attenuate morphological and behavioral impact of pilocarpine-induced epilepsy |
Q47781966 | Site-Specific Regulation of P2X7 Receptor Function in Microglia Gates Morphine Analgesic Tolerance. |
Q34081777 | Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis |
Q47923743 | Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease |
Q58104043 | TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation |
Q38956264 | The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy |
Q92538952 | The CD40-ATP-P2X 7 Receptor Pathway: Cell to Cell Cross-Talk to Promote Inflammation and Programmed Cell Death of Endothelial Cells |
Q58787876 | The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases |
Q55384599 | The P2X7 receptor and pannexin-1 are involved in glucose-induced autocrine regulation in β-cells. |
Q42286459 | The P2X7 receptor forms a dye-permeable pore independent of its intracellular domain but dependent on membrane lipid composition. |
Q34531684 | The P2X7 receptor supports both life and death in fibrogenic pancreatic stellate cells |
Q64095098 | The Role of Connexin and Pannexin Channels in Perinatal Brain Injury and Inflammation |
Q26777950 | The Role of Ion Channels in Microglial Activation and Proliferation - A Complex Interplay between Ligand-Gated Ion Channels, K(+) Channels, and Intracellular Ca(2.) |
Q30540124 | The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice. |
Q91627120 | The role and therapeutic potential of heat shock proteins in haemorrhagic stroke |
Q41034427 | The role of microglial P2X7: modulation of cell death and cytokine release |
Q48947439 | The roles of P2X7 receptor in regional-specific microglial responses in the rat brain following status epilepticus |
Q26824833 | The two-hit hypothesis for neuroinflammation: role of exogenous ATP in modulating inflammation in the brain |
Q46601743 | Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy. |
Q34195588 | Trophic activity of human P2X7 receptor isoforms A and B in osteosarcoma. |
Q26798961 | Understanding the role of P2X7 in affective disorders-are glial cells the major players? |
Q36015724 | Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development-Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus |
Q44269727 | Valproic acid attenuates microgliosis in injured spinal cord and purinergic P2X4 receptor expression in activated microglia |
Q39012371 | l-DOPA-induced dyskinesia and neuroinflammation: do microglia and astrocytes play a role? |
Q36343295 | microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus |
Q42368047 | αVβ3 Integrin regulates astrocyte reactivity |
Search more.